AT4G22200.1
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Subcellular Consensus
(Prediction and Experimental) min:  :max.
SUBAcon:plasma membrane 0.999 What is SUBAcon? |
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| Experimental Localisations and PPI |
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SUBAcon links
AGI-AGI relationships |
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| Description (TAIR10) | protein_coding : potassium transport 2/3 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Curator Summary (TAIR10) |
Encodes AKT2, a photosynthate- and light-dependent inward rectifying potassium channel with unique gating properties that are regulated by phosphorylation. Expressed in guard cell protoplasts and in the phloem and xylem of aerial portions of the plant. The channel can coassemble with another K+ channel, KAT1, in vitro. In guard cells, AKT2/3 is responsible for the Ca2+ sensitivity of the K+ uptake channel. In the phloem, it regulates the sucrose/H+ symporters via the phloem potential. AKT2 belongs to the Shaker family K+ channels which include the following groups based on phylogenetic analysis (FEBS Letters (2007) 581: 2357): I (inward rectifying channel): AKT1 (AT2G26650), AKT5 (AT4G32500) and SPIK (also known as AKT6, AT2G25600); II (inward rectifying channel): KAT1 (AT5G46240) and KAT2 (AT4G18290); III (weakly inward rectifying channel): AKT2 (AT4G22200); IV (regulatory subunit involved in inwardly rectifying conductance formation): KAT3 (also known as AtKC1, AT4G32650); V (outward rectifying channel): SKOR (AT3G02850) and GORK (AT5G37500). | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Computational Description (TAIR10) |
potassium transport 2/3 (KT2/3); FUNCTIONS IN: inward rectifier potassium channel activity, protein binding, cyclic nucleotide binding; INVOLVED IN: regulation of membrane potential, response to abscisic acid stimulus; LOCATED IN: membrane; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Cyclic nucleotide-binding (InterPro:IPR000595), Potassium channel, voltage-dependent, EAG/ELK/ERG (InterPro:IPR003938), Protein of unknown function DUF3354 (InterPro:IPR021789), Ankyrin repeat-containing domain (InterPro:IPR020683), Ion transport (InterPro:IPR005821), Cyclic nucleotide-binding-like (InterPro:IPR018490), RmlC-like jelly roll fold (InterPro:IPR014710), Ankyrin repeat (InterPro:IPR002110); BEST Arabidopsis thaliana protein match is: K+ transporter 1 (TAIR:AT2G26650.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink). | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Protein Annotations |
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| Coordinates (TAIR10) | chr4:-:11746666..11750091 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Molecular Weight (calculated) | 91313.50 Da | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| IEP (calculated) | 6.51 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| GRAVY (calculated) | -0.06 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Length | 802 amino acids | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Sequence (TAIR10) (BLAST) |
001: MDLKYSASHC NLSSDMKLRR FHQHRGKGRE EEYDASSLSL NNLSKLILPP LGVASYNQNH IRSSGWIISP MDSRYRCWEF YMVLLVAYSA WVYPFEVAFL 101: NSSPKRNLCI ADNIVDLFFA VDIVLTFFVA YIDERTQLLV REPKQIAVRY LSTWFLMDVA STIPFDAIGY LITGTSTLNI TCNLLGLLRF WRLRRVKHLF 201: TRLEKDIRYS YFWIRCFRLL SVTLFLVHCA GCSYYLIADR YPHQGKTWTD AIPNFTETSL SIRYIAAIYW SITTMTTVGY GDLHASNTIE MVFITVYMLF 301: NLGLTAYLIG NMTNLVVEGT RRTMEFRNSI EAASNFVNRN RLPPRLKDQI LAYMCLRFKA ESLNQQHLID QLPKSIYKSI CQHLFLPSVE KVYLFKGVSR 401: EILLLLVSKM KAEYIPPRED VIMQNEAPDD VYIIVSGEVE IIDSEMERES VLGTLRCGDI FGEVGALCCR PQSYTFQTKS LSQLLRLKTS FLIETMQIKQ 501: QDNATMLKNF LQHHKKLSNL DIGDLKAQQN GENTDVVPPN IASNLIAVVT TGNAALLDEL LKAKLSPDIT DSKGKTPLHV AASRGYEDCV LVLLKHGCNI 601: HIRDVNGNSA LWEAIISKHY EIFRILYHFA AISDPHIAGD LLCEAAKQNN VEVMKALLKQ GLNVDTEDHH GVTALQVAMA EDQMDMVNLL ATNGADVVCV 701: NTHNEFTPLE KLRVVEEEEE EERGRVSIYR GHPLERRERS CNEAGKLILL PPSLDDLKKI AGEKFGFDGS ETMVTNEDGA EIDSIEVIRD NDKLYFVVNK 801: II |
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| See Also |
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Citation
If you find this resource useful please cite one of the following publications:
Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)
Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)