suba logo
AT4G21750.1
Subcellular Consensus
(Prediction and Experimental)
min: heatmap :max

.
SUBAcon:
nucleus 1.000
ASURE: nucleus
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no PPI data
Description (TAIR10) protein_coding : Homeobox-leucine zipper family protein / lipid-binding START domain-containing protein
Curator
Summary (TAIR10)
Encodes a homeobox protein similar to GL2. It is expressed in both the apical and basal daughter cells of the zygote as well as their progeny. Expression is detected starting the two-celled stage of embryo development and is later restricted to the outermost, epidermal cell layer from its inception. Its promoter is highly modular with each region contributing to specific aspects of the gene's spatial and temporal expression. Double mutant analysis with PDF2, another L1-specific gene, suggests that their functions are partially redundant and the absence of both of the genes result in abnormal shoot development.
Computational
Description (TAIR10)
MERISTEM LAYER 1 (ATML1); FUNCTIONS IN: sequence-specific DNA binding, DNA binding, sequence-specific DNA binding transcription factor activity; INVOLVED IN: epidermal cell differentiation, regulation of transcription, DNA-dependent, cotyledon development; LOCATED IN: nucleus; EXPRESSED IN: 29 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Homeobox, conserved site (InterPro:IPR017970), Homeobox (InterPro:IPR001356), Homeodomain-like (InterPro:IPR009057), Lipid-binding START (InterPro:IPR002913), Homeodomain-related (InterPro:IPR012287); BEST Arabidopsis thaliana protein match is: protodermal factor 2 (TAIR:AT4G04890.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).
Protein Annotations
BioGrid:13552eggNOG:ENOG410IIN5eggNOG:ENOG411107HEMBL:AK229970
EMBL:AL035527EMBL:AL161555EMBL:AY091104EMBL:AY150491
EMBL:CP002687EMBL:U37589EnsemblPlants:AT4G21750EnsemblPlants:AT4G21750.1
EnsemblPlants:AT4G21750.2entrez:828263Gene3D:1.10.10.60Gene3D:3.30.530.20
GeneID:828263Genevisible:Q8RWU4GO:GO:0003677GO:GO:0003700
GO:GO:0005634GO:GO:0006351GO:GO:0008289GO:GO:0009845
GO:GO:0043565GO:GO:0048825GO:GO:0090627Gramene:AT4G21750.1
Gramene:AT4G21750.2hmmpanther:PTHR24326hmmpanther:PTHR24326:SF294HOGENOM:HOG000243256
InParanoid:Q8RWU4InterPro:IPR001356InterPro:IPR002913InterPro:IPR009057
InterPro:IPR017970InterPro:IPR023393iPTMnet:Q8RWU4KEGG:ath:AT4G21750
ncoils:CoilOMA:NSGQSNMPaxDb:Q8RWU4Pfam:PF00046
Pfam:PF01852Pfam:Q8RWU4Pfscan:PS50071Pfscan:PS50848
PhylomeDB:Q8RWU4PIR:T05850PRIDE:Q8RWU4PRO:PR:Q8RWU4
PROSITE:PS00027PROSITE:PS50071PROSITE:PS50848ProteinModelPortal:Q8RWU4
Proteomes:UP000006548RefSeq:NP_001031692.1RefSeq:NP_193906.2scanprosite:PS00027
SMART:SM00234SMART:SM00389SMR:Q8RWU4STRING:3702.AT4G21750.1
SUPFAM:SSF46689SUPFAM:SSF55961TAIR:AT4G21750tair10-symbols:ATML1
UniGene:At.2706UniProt:Q8RWU4
Coordinates (TAIR10) chr4:+:11556965..11560243
Molecular Weight (calculated) 83494.80 Da
IEP (calculated) 5.72
GRAVY (calculated) -0.34
Length 762 amino acids
Sequence (TAIR10)
(BLAST)
001: MYHPNMFESH HHMFDMTPKN SENDLGITGS HEEDFETKSG AEVTMENPLE EELQDPNQRP NKKKRYHRHT QRQIQELESF FKECPHPDDK QRKELSRELS
101: LEPLQVKFWF QNKRTQMKAQ HERHENQILK SENDKLRAEN NRYKDALSNA TCPNCGGPAA IGEMSFDEQH LRIENARLRE EIDRISAIAA KYVGKPLMAN
201: SSSFPQLSSS HHIPSRSLDL EVGNFGNNNN SHTGFVGEMF GSSDILRSVS IPSEADKPMI VELAVAAMEE LVRMAQTGDP LWVSSDNSVE ILNEEEYFRT
301: FPRGIGPKPI GLRSEASRES TVVIMNHINL IEILMDVNQW SSVFCGIVSR ALTLEVLSTG VAGNYNGALQ VMTAEFQVPS PLVPTRENYF VRYCKQHSDG
401: IWAVVDVSLD SLRPSPITRS RRRPSGCLIQ ELQNGYSKVT WVEHIEVDDR SVHNMYKPLV NTGLAFGAKR WVATLDRQCE RLASSMASNI PACDLSVITS
501: PEGRKSMLKL AERMVMSFCT GVGASTAHAW TTLSTTGSDD VRVMTRKSMD DPGRPPGIVL SAATSFWIPV APKRVFDFLR DENSRSEWDI LSNGGLVQEM
601: AHIANGRDPG NSVSLLRVNS GNSGQSNMLI LQESCTDASG SYVIYAPVDI IAMNVVLSGG DPDYVALLPS GFAILPDGSA RGGGGSANAS AGAGVEGGGE
701: GNNLEVVTTT GSCGGSLLTV AFQILVDSVP TAKLSLGSVA TVNSLIKCTV ERIKAALACD GA
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)