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AT4G19710.1
Subcellular Consensus
(Prediction and Experimental)

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SUBAcon:
plastid 1.000
What is SUBAcon?
What is ASURE?
SUBAcon computations
Experimental Localisations and PPI
FP MS/MS PPI
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no PPI data
Description (TAIR10) protein_coding : aspartate kinase-homoserine dehydrogenase ii
Curator
Summary (TAIR10)
Encodes a bifunctional aspartate kinase/homoserine dehydrogenase. These two activities catalyze the first and the third steps toward the synthesis of the essential amino acids threonine, isoleucine and methionine.
Computational
Description (TAIR10)
aspartate kinase-homoserine dehydrogenase ii (AK-HSDH II); FUNCTIONS IN: homoserine dehydrogenase activity, aspartate kinase activity; INVOLVED IN: aspartate family amino acid biosynthetic process; LOCATED IN: chloroplast; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Aspartate/glutamate/uridylate kinase (InterPro:IPR001048), Homoserine dehydrogenase, catalytic (InterPro:IPR001342), Amino acid-binding ACT (InterPro:IPR002912), Aspartate/homoserine dehydrogenase, NAD-binding (InterPro:IPR005106), Aspartate kinase, conserved site (InterPro:IPR018042), Bifunctional aspartokinase/homoserine dehydrogenase I (InterPro:IPR011147), Aspartate kinase domain (InterPro:IPR001341), NAD(P)-binding domain (InterPro:IPR016040), Homoserine dehydrogenase, conserved site (InterPro:IPR019811); BEST Arabidopsis thaliana protein match is: aspartate kinase-homoserine dehydrogenase i (TAIR:AT1G31230.1); Has 17435 Blast hits to 17108 proteins in 2575 species: Archae - 421; Bacteria - 11654; Metazoa - 7; Fungi - 299; Plants - 259; Viruses - 0; Other Eukaryotes - 4795 (source: NCBI BLink).
Protein Annotations
EnsemblPlants:AT4G19710EnsemblPlants:AT4G19710.1entrez:827715gramene_pathway:1.1.1.3gramene_pathway:2.7.2.4gramene_pathway:HOMOSERSYN-PWYgramene_pathway:PWY-5097
hmmpanther:PTHR21499hmmpanther:PTHR21499:SF30KEGG:00260+1.1.1.3KEGG:00260+1.1.1.3+2.7.2.4KEGG:00260+2.7.2.4KEGG:00261+2.7.2.4KEGG:00270+1.1.1.3
KEGG:00270+1.1.1.3+2.7.2.4KEGG:00270+2.7.2.4KEGG:00300+1.1.1.3KEGG:00300+1.1.1.3+2.7.2.4KEGG:00300+2.7.2.4Pfam:PF00696Pfam:PF00742
Pfam:PF01842Pfam:PF03447Pfam:PF13840Pfscan:PS51671scanprosite:PS00324scanprosite:PS01042SUPFAM:SSF55021
SUPFAM:SSF55347tair10-symbols:AK-HSDHtair10-symbols:AK-HSDH IITIGRfam:TIGR00657unipathway:UPA00034unipathway:UPA00050unipathway:UPA00051
Coordinates (TAIR10) chr4:+:10725229..10729278
Molecular Weight (calculated) 94431.60 Da
IEP (calculated) 6.78
GRAVY (calculated) -0.06
Length 859 amino acids
Sequence (TAIR10)
(BLAST)
001: MATLKPSFTV SPPNSNPIRF GSFPPQCFLR VPKPRRLILP RFRKTTGGGG GLIRCELPDF HLSATATTVS GVSTVNLVDQ VQIPKGEMWS VHKFGGTCVG
101: NSQRIRNVAE VIINDNSERK LVVVSAMSKV TDMMYDLIRK AQSRDDSYLS ALEAVLEKHR LTARDLLDGD DLASFLSHLH NDISNLKAML RAIYIAGHAS
201: ESFSDFVAGH GELWSAQMLS YVVRKTGLEC KWMDTRDVLI VNPTSSNQVD PDFGESEKRL DKWFSLNPSK IIIATGFIAS TPQNIPTTLK RDGSDFSAAI
301: MGALLRARQV TIWTDVDGVY SADPRKVNEA VILQTLSYQE AWEMSYFGAN VLHPRTIIPV MRYNIPIVIR NIFNLSAPGT IICQPPEDDY DLKLTTPVKG
401: FATIDNLALI NVEGTGMAGV PGTASDIFGC VKDVGANVIM ISQASSEHSV CFAVPEKEVN AVSEALRSRF SEALQAGRLS QIEVIPNCSI LAAVGQKMAS
501: TPGVSCTLFS ALAKANINVR AISQGCSEYN VTVVIKREDS VKALRAVHSR FFLSRTTLAM GIVGPGLIGA TLLDQLRDQA AVLKQEFNID LRVLGITGSK
601: KMLLSDIGID LSRWRELLNE KGTEADLDKF TQQVHGNHFI PNSVVVDCTA DSAIASRYYD WLRKGIHVIT PNKKANSGPL DQYLKLRDLQ RKSYTHYFYE
701: ATVGAGLPII STLRGLLETG DKILRIEGIC SGTLSYLFNN FVGDRSFSEV VTEAKNAGFT EPDPRDDLSG TDVARKVIIL ARESGLKLDL ADLPIRSLVP
801: EPLKGCTSVE EFMEKLPQYD GDLAKERLDA ENSGEVRLFT TNVFPFDQCD HILTIYICM
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)