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AT4G19040.1
Subcellular Consensus
(Prediction and Experimental)
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SUBAcon:
plasma membrane 1.000
ASURE: plasma membrane
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
  • PMID:17612410 (2007): endoplasmic reticulum
  • PMID:17612410 (2007): plasma membrane
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no PPI data
Description (TAIR10) protein_coding : ENHANCED DISEASE RESISTANCE 2
Curator
Summary (TAIR10)
Encodes a PH and START domain-containing protein that mediates resistance to pathogenic fungi. Resistance requires salicylic acid signalling. Mutants are resistant to E. cichoracearum. Expressed throughout plant tissues and possibly localized to membranes /mitochondrion.
Computational
Description (TAIR10)
ENHANCED DISEASE RESISTANCE 2 (EDR2); FUNCTIONS IN: lipid binding; INVOLVED IN: biological_process unknown; LOCATED IN: plasma membrane; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Protein of unknown function DUF1336 (InterPro:IPR009769), Pleckstrin homology-type (InterPro:IPR011993), Lipid-binding START (InterPro:IPR002913), Pleckstrin homology (InterPro:IPR001849); BEST Arabidopsis thaliana protein match is: Pleckstrin homology (PH) domain-containing protein / lipid-binding START domain-containing protein (TAIR:AT5G45560.1); Has 517 Blast hits to 508 proteins in 73 species: Archae - 0; Bacteria - 2; Metazoa - 69; Fungi - 0; Plants - 351; Viruses - 0; Other Eukaryotes - 95 (source: NCBI BLink).
Protein Annotations
eggNOG:ENOG410IHYEeggNOG:ENOG4112846EMBL:AK222155EMBL:AL021711
EMBL:AL161550EMBL:AY090340EMBL:BX827233EMBL:CP002687
EnsemblPlants:AT4G19040EnsemblPlants:AT4G19040.1EnsemblPlants:AT4G19040.2EnsemblPlants:AT4G19040.3
entrez:827642ExpressionAtlas:F4JSE7Gene3D:2.30.29.30Gene3D:3.30.530.20
GeneID:827642Genevisible:F4JSE7GO:GO:0005789GO:GO:0005886
GO:GO:0009626GO:GO:0009723GO:GO:0009751GO:GO:0009873
GO:GO:0010008GO:GO:0016021GO:GO:0070273GO:GO:1900056
GO:GO:1900150hmmpanther:PTHR12136hmmpanther:PTHR12136:SF47HOGENOM:HOG000005741
InterPro:IPR001849InterPro:IPR002913InterPro:IPR009769InterPro:IPR011993
InterPro:IPR023393iPTMnet:F4JSE7KEGG:ath:AT4G19040PaxDb:F4JSE7
Pfam:F4JSE7Pfam:PF00169Pfam:PF01852Pfam:PF07059
Pfscan:PS50003Pfscan:PS50848PIR:T05041PRIDE:F4JSE7
PRO:PR:F4JSE7PROSITE:PS50003PROSITE:PS50848ProteinModelPortal:F4JSE7
Proteomes:UP000006548RefSeq:NP_001119010.1RefSeq:NP_001190769.1RefSeq:NP_193639.2
SMART:SM00233SMART:SM00234STRING:3702.AT4G19040.2SUPFAM:SSF50729
SUPFAM:SSF55961TAIR:AT4G19040tair10-symbols:EDR2UniGene:At.32844
UniProt:F4JSE7
Coordinates (TAIR10) chr4:-:10431799..10437171
Molecular Weight (calculated) 81851.40 Da
IEP (calculated) 6.71
GRAVY (calculated) -0.47
Length 718 amino acids
Sequence (TAIR10)
(BLAST)
001: MSKVVYEGWM VRYGRRKIGR SYIHMRYFVL EPRLLAYYKK KPQDYQVPIK TMLIDGNCRV EDRGLKTHHG HMVYVLSVYN KKEKSHRITM AAFNIQEALM
101: WKEKIESVID QHQESQVPNG QQYVSFEYKS GMDTGRTASS SDHESQFSAA EDEEDSRRSL MRRTTIGNGP PESVLDWTKE FDAELANQNS DNQAFSRKHW
201: RLLQCQNGLR IFEELLEVDY LPRSCSRAMK AVGVVEATCE EIFELLMSMD GTRYEWDCSF QFGSLVEEVD GHTAVLYHRL LLDWFPMIVW PRDLCYVRYW
301: RRNDDGSYVV LFRSREHENC GPQPGCVRAH LESGGYNISP LKPRNGRPRT QVQHLIQIDL KGWGAGYLPA FQQHCLLQML NSVAGLREWF SQTDERGVHT
401: RIPVMVNMAS SSLSLTKSGK SLHKSAFSLD QTNSVNRNSL LMDEDSDDDD EFQIAESEQE PETSKPETDV KRPEEEPAHN IDLSCFSGNL KRNENENARN
501: CWRISDGNNF KVRGKNFGQE KRKIPAGKHL MDLVAVDWFK DSKRIDHVAR RKGCAAQVAA EKGLFSMVVN VQVPGSTHYS MVFYFVMKEL VPGSLLQRFV
601: DGDDEFRNSR LKLIPLVPKG SWIVRQSVGS TPCLLGKAVD CNYIRGPTYL EIDVDIGSST VANGVLGLVI GVITSLVVEM AFLVQANTAE EQPERLIGAV
701: RVSHIELSSA IVPNLESE
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)