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AT4G18710.1
Subcellular Consensus
(Prediction and Experimental)

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SUBAcon:
cytosol 0.957
What is SUBAcon?
What is ASURE?
SUBAcon computations
Experimental Localisations and PPI
FP MS/MS PPI
SUBAcon links
AGI-AGI relationships
Coexpression PPI
Description (TAIR10) protein_coding : Protein kinase superfamily protein
Curator
Summary (TAIR10)
ATSK (shaggy-like kinase) family member that encodes an AtSK protein involved in the cross-talk between auxin and brassinosteroid signaling pathways. BR-INSENSITIVE 2 mutant indicated that the BR-insensitive dwarf phenotype was due to a semidominant mutation in the BIN2. BIN2 is not allelic to BRI1. BIN2-mediated phosphorylation appears to promote BZR1 export from the nucleus.
Computational
Description (TAIR10)
BRASSINOSTEROID-INSENSITIVE 2 (BIN2); FUNCTIONS IN: protein kinase activity, kinase activity, glycogen synthase kinase 3 activity; INVOLVED IN: in 7 processes; LOCATED IN: plasma membrane; EXPRESSED IN: 29 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Protein kinase, ATP binding site (InterPro:IPR017441), Protein kinase, catalytic domain (InterPro:IPR000719), Serine/threonine-protein kinase domain (InterPro:IPR002290), Serine/threonine-protein kinase-like domain (InterPro:IPR017442), Protein kinase-like domain (InterPro:IPR011009), Serine/threonine-protein kinase, active site (InterPro:IPR008271); BEST Arabidopsis thaliana protein match is: SHAGGY-related protein kinase dZeta (TAIR:AT2G30980.1); Has 110203 Blast hits to 108729 proteins in 3938 species: Archae - 86; Bacteria - 11182; Metazoa - 39944; Fungi - 12089; Plants - 27852; Viruses - 403; Other Eukaryotes - 18647 (source: NCBI BLink).
Protein Annotations
BioCyc:ARA:AT4G18710-MONOMERBioCyc:ARA:GQT-2728-MONOMERBioGrid:12898BRENDA:2.7.11.26DIP:DIP-46010NEC:2.7.11.1eggNOG:COG0515
eggNOG:KOG0658EMBL:AL035526EMBL:AL161549EMBL:AY075699EMBL:AY086529EMBL:AY157149EMBL:BT026031
EMBL:CP002687EMBL:X94939EMBL:Y08947EnsemblPlants:AT4G18710EnsemblPlants:AT4G18710.1entrez:827605ExpressionAtlas:Q39011
GeneID:827605Genevisible:Q39011GO:GO:0004672GO:GO:0004674GO:GO:0005524GO:GO:0005886GO:GO:0006468
GO:GO:0009729GO:GO:0009733GO:GO:0009742GO:GO:0009825GO:GO:0009965GO:GO:0016032GO:GO:0046777
GO:GO:0046827GO:GO:0048765hmmpanther:PTHR24057hmmpanther:PTHR24057:SF5HOGENOM:HOG000233017InParanoid:Q39011IntAct:Q39011
InterPro:IPR000719InterPro:IPR008271InterPro:IPR011009InterPro:IPR017441iPTMnet:Q39011MINT:MINT-8146086OMA:KHGASLM
PaxDb:Q39011Pfam:PF00069Pfam:Q39011Pfscan:PS50011PhylomeDB:Q39011PIR:T04863PRIDE:Q39011
PRO:PR:Q39011PROSITE:PS00107PROSITE:PS00108PROSITE:PS50011ProteinModelPortal:Q39011Proteomes:UP000006548Reactome:R-ATH-3371453
RefSeq:NP_193606.1scanprosite:PS00107scanprosite:PS00108SMART:SM00220SMR:Q39011STRING:3702.AT4G18710.1SUPFAM:SSF56112
TAIR:AT4G18710tair10-symbols:ATSK21tair10-symbols:BIN2tair10-symbols:DWF12tair10-symbols:SK21tair10-symbols:UCU1UniGene:At.22875
UniProt:Q39011
Coordinates (TAIR10) chr4:+:10296474..10298913
Molecular Weight (calculated) 43101.30 Da
IEP (calculated) 8.26
GRAVY (calculated) -0.19
Length 380 amino acids
Sequence (TAIR10)
(BLAST)
001: MADDKEMPAA VVDGHDQVTG HIISTTIGGK NGEPKQTISY MAERVVGTGS FGIVFQAKCL ETGETVAIKK VLQDRRYKNR ELQLMRVMDH PNVVCLKHCF
101: FSTTSKDELF LNLVMEYVPE SLYRVLKHYS SANQRMPLVY VKLYMYQIFR GLAYIHNVAG VCHRDLKPQN LLVDPLTHQV KICDFGSAKQ LVKGEANISY
201: ICSRFYRAPE LIFGATEYTT SIDIWSAGCV LAELLLGQPL FPGENAVDQL VEIIKVLGTP TREEIRCMNP HYTDFRFPQI KAHPWHKIFH KRMPPEAIDF
301: ASRLLQYSPS LRCTALEACA HPFFDELREP NARLPNGRPF PPLFNFKQEV AGSSPELVNK LIPDHIKRQL GLSFLNQSGT
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)