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AT4G16845.1
Subcellular Consensus
(Prediction and Experimental)

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SUBAcon:
nucleus 1.000
ASURE: nucleus
What is SUBAcon?
What is ASURE?
SUBAcon computations
Experimental Localisations and PPI
FP MS/MS PPI
SUBAcon links
AGI-AGI relationships
Coexpression PPI
Description (TAIR10) protein_coding : VEFS-Box of polycomb protein
Curator
Summary (TAIR10)
The VERNALIZATION2 (VRN2) gene mediates vernalization and encodes a nuclear-localized zinc finger protein with similarity to Polycomb group (PcG) proteins of plants and animals. In wild-type Arabidopsis, vernalization results in the stable reduction of the levels of the floral repressor FLC. In vrn2 mutants, FLC expression is downregulated normally in response to vernalization, but instead of remaining low, FLC mRNA levels increase when plants are returned to normal temperatures. VRN2 maintains FLC repression after a cold treatment, serving as a mechanism for the cellular memory of vernalization. Required for complete repression of FLC. Required for the methylation of histone H3
Computational
Description (TAIR10)
REDUCED VERNALIZATION RESPONSE 2 (VRN2); CONTAINS InterPro DOMAIN/s: Polycomb protein, VEFS-Box (InterPro:IPR019135); BEST Arabidopsis thaliana protein match is: VEFS-Box of polycomb protein (TAIR:AT5G51230.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).
Protein Annotations
BioGrid:12685DIP:DIP-48610NeggNOG:ENOG410YJ29eggNOG:KOG2350EMBL:AF284500EMBL:AF284501EMBL:AL161545
EMBL:AY034902EMBL:AY063047EMBL:CP002687EMBL:Z97342EnsemblPlants:AT4G16845EnsemblPlants:AT4G16845.1entrez:827392
ExpressionAtlas:Q8W5B1GeneID:827392Genevisible:Q8W5B1GO:GO:0003700GO:GO:0005634GO:GO:0005677GO:GO:0006349
GO:GO:0006351GO:GO:0009409GO:GO:0010048GO:GO:0046872hmmpanther:PTHR22597HOGENOM:HOG000083848InParanoid:Q8W5B1
IntAct:Q8W5B1InterPro:IPR019135KEGG:ath:AT4G16845OMA:HDLFEFEPaxDb:Q8W5B1Pfam:PF09733Pfam:Q8W5B1
PhylomeDB:Q8W5B1PIR:G71435PRIDE:Q8W5B1PRO:PR:Q8W5B1PROSITE:PS00028ProteinModelPortal:Q8W5B1Proteomes:UP000006548
RefSeq:NP_567517.1STRING:3702.AT4G16845.1TAIR:AT4G16845tair10-symbols:VRN2UniGene:At.11901UniGene:At.19153UniProt:Q8W5B1
Coordinates (TAIR10) chr4:+:9476708..9479725
Molecular Weight (calculated) 50626.50 Da
IEP (calculated) 7.10
GRAVY (calculated) -0.67
Length 440 amino acids
Sequence (TAIR10)
(BLAST)
001: MCRQNCRAKS SPEEVISTDE NLLIYCKPVR LYNIFHLRSL GNPSFLPRCL NYKIGAKRKR KSRSTGMVVF NYKDCNNTLQ RTEVREDCSC PFCSMLCGSF
101: KGLQFHLNSS HDLFEFEFKL LEEYQTVNVS VKLNSFIFEE EGSDDDKFEP FSLCSKPRKR RQRGGRNNTR RLKVCFLPLD SPSLANGTEN GIALLNDGNR
201: GLGYPEATEL AGQFEMTSNI PPAIAHSSLD AGAKVILTTE AVVPATKTRK LSAERSEARS HLLLQKRQFY HSHRVQPMAL EQVMSDRDSE DEVDDDVADF
301: EDRQMLDDFV DVNKDEKQFM HLWNSFVRKQ RVIADGHISW ACEVFSRFYE KELHCYSSLF WCWRLFLIKL WNHGLVDSAT INNCNTILEN CRNTSVTNNN
401: NNSVDHPSDS NTNNNNIVDH PNDIKNKNNV DNKDNNSRDK
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)