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AT4G16143.1
Subcellular Consensus
(Prediction and Experimental)

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SUBAcon:
nucleus 1.000
ASURE: nucleus
What is SUBAcon?
What is ASURE?
SUBAcon computations
Experimental Localisations and PPI
FP MS/MS PPI
  • PMID:26781341 (2016): plasma membrane
  • PMID:26572690 (2016): extracellular region plant-type cell wall
  • PMID:25900983 (2015): plant-type vacuole plant-type vacuole membrane
  • PMID:25900983 (2015): Golgi trans-Golgi network multivesicular body
  • PMID:25900983 (2015): Golgi trans-Golgi network early endosome
  • PMID:25900983 (2015): Golgi trans-Golgi network
  • PMID:25900983 (2015): Golgi Golgi apparatus Golgi membrane
  • PMID:25900983 (2015): Golgi
  • PMID:23396599 (2013): nucleus nuclear envelope nuclear inner membrane
  • PMID:22215637 (2012): plasma membrane
  • PMID:21166475 (2011): cytosol
  • PMID:18433157 (2008): cytosol
  • PMID:15496452 (2005): nucleus
SUBAcon links
AGI-AGI relationships
Coexpression PPI
Description (TAIR10) protein_coding : importin alpha isoform 2
Curator
Summary (TAIR10)
Protein interacts with Agrobacterium proteins VirD2 and VirE2. Is not individually essential for Agrobacterium-mediated root transformation, but when overexpressed can rescue the impa-4 decreased transformation susceptibility phenotype.
Computational
Description (TAIR10)
importin alpha isoform 2 (IMPA-2); FUNCTIONS IN: protein transporter activity, binding; INVOLVED IN: intracellular protein transport, protein import into nucleus; LOCATED IN: cytosol, nucleolus; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Importin-alpha-like, importin-beta-binding domain (InterPro:IPR002652), Armadillo-like helical (InterPro:IPR011989), Armadillo (InterPro:IPR000225), Armadillo-type fold (InterPro:IPR016024); BEST Arabidopsis thaliana protein match is: importin alpha isoform 1 (TAIR:AT3G06720.2); Has 4654 Blast hits to 3364 proteins in 293 species: Archae - 4; Bacteria - 33; Metazoa - 1869; Fungi - 640; Plants - 1336; Viruses - 0; Other Eukaryotes - 772 (source: NCBI BLink).
Protein Annotations
eggNOG:COG5064eggNOG:KOG0166EMBL:AF361811EMBL:AL161543EMBL:AY060529EMBL:CP002687EMBL:Y14615
EnsemblPlants:AT4G16143EnsemblPlants:AT4G16143.1EnsemblPlants:AT4G16143.2entrez:827302Gene3D:1.25.10.10GeneID:827302Genevisible:F4JL11
GO:GO:0005643GO:GO:0005654GO:GO:0005730GO:GO:0005829GO:GO:0006607GO:GO:0008139GO:GO:0008565
GO:GO:0009506Gramene:AT4G16143.1Gramene:AT4G16143.2hmmpanther:PTHR23316hmmpanther:PTHR23316:SF22HOGENOM:HOG000167616InParanoid:F4JL11
IntAct:F4JL11InterPro:IPR000225InterPro:IPR002652InterPro:IPR011989InterPro:IPR016024InterPro:IPR024931InterPro:IPR032413
KEGG:ath:AT4G16143OMA:VFAQMIDPaxDb:F4JL11Pfam:F4JL11Pfam:PF00514Pfam:PF01749Pfam:PF16186
Pfscan:PS50176Pfscan:PS51214PIR:T52098PIRSF:PIRSF005673PRIDE:F4JL11PRO:PR:F4JL11PROSITE:PS50176
PROSITE:PS51214ProteinModelPortal:F4JL11Proteomes:UP000006548RefSeq:NP_001154239.1RefSeq:NP_567485.4SMART:SM00185SMR:F4JL11
STRING:3702.AT4G16143.1SUPFAM:SSF48371TAIR:AT4G16143tair10-symbols:IMPA-2UniGene:At.21119UniProt:F4JL11
Coordinates (TAIR10) chr4:-:9134450..9137134
Molecular Weight (calculated) 58910.10 Da
IEP (calculated) 4.74
GRAVY (calculated) -0.27
Length 535 amino acids
Sequence (TAIR10)
(BLAST)
001: MSLRPNAKTE VRRNRYKVAV DAEEGRRRRE DNMVEIRKSK REESLQKKRR EGLQANQLPQ FAPSPVPASS TVEKKLESLP AMVGGVWSDD RSLQLEATTQ
101: FRKLLSIERS PPIEEVIDAG VVPRFVEFLT REDYPQLQFE AAWALTNIAS GTSENTKVVI EHGAVPIFVQ LLASQSDDVR EQAVWALGNV AGDSPRCRDL
201: VLGQGALIPL LSQLNEHAKL SMLRNATWTL SNFCRGKPQP PFDQVRPALP ALERLIHSTD EEVLTDACWA LSYLSDGTND KIQSVIEAGV VPRLVELLQH
301: QSPSVLIPAL RSIGNIVTGD DLQTQCVISH GALLSLLSLL THNHKKSIKK EACWTISNIT AGNRDQIQAV CEAGLICPLV NLLQNAEFDI KKEAAWAISN
401: ATSGGSPDQI KYMVEQGVVK PLCDLLVCPD PRIITVCLEG LENILKVGEA EKVTGNTGDV NFYAQLIDDA EGLEKIENLQ SHDNSEIYEK AVKILETYWL
501: EEEDETLPPG DPSAQGFQFG GGNDAAVPPG GFNFQ
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)