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AT4G15900.1
Subcellular Consensus
(Prediction and Experimental)

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SUBAcon:
nucleus 1.000
ASURE: nucleus
What is SUBAcon?
What is ASURE?
SUBAcon computations
Experimental Localisations and PPI
FP MS/MS PPI
  • PMID:27177187 (2016): nucleus
  • PMID:24134884 (2013): cytoskeleton microtubules
  • PMID:23396599 (2013): nucleus nuclear envelope nuclear inner membrane
SUBAcon links
AGI-AGI relationships
Coexpression PPI
Description (TAIR10) protein_coding : pleiotropic regulatory locus 1
Curator
Summary (TAIR10)
Mutations confer hypersensitivity to glucose and sucrose and augments sensitivity to cytokinin, ethylene, ABA and auxin. Encodes a nuclear WD40 protein that is imported into the nucleus. Essential for plant innate immunity. Interacts with MOS4 and AtCDC5. It is also predicted to have two DWD motifs. It can bind to DDB1a in Y2H assays, and DDB1b in co-IP assays, and may be involved in the formation of a CUL4-based E3 ubiquitin ligase, and may affect the stability of AKIN10.
Computational
Description (TAIR10)
pleiotropic regulatory locus 1 (PRL1); CONTAINS InterPro DOMAIN/s: WD40 repeat 2 (InterPro:IPR019782), WD40 repeat, conserved site (InterPro:IPR019775), WD40 repeat (InterPro:IPR001680), G-protein beta WD-40 repeat, region (InterPro:IPR020472), WD40 repeat-like-containing domain (InterPro:IPR011046), WD40-repeat-containing domain (InterPro:IPR017986), WD40/YVTN repeat-like-containing domain (InterPro:IPR015943), WD40 repeat, subgroup (InterPro:IPR019781); BEST Arabidopsis thaliana protein match is: Transducin/WD40 repeat-like superfamily protein (TAIR:AT3G16650.1); Has 84704 Blast hits to 34179 proteins in 878 species: Archae - 64; Bacteria - 9610; Metazoa - 34201; Fungi - 18356; Plants - 10881; Viruses - 0; Other Eukaryotes - 11592 (source: NCBI BLink).
Protein Annotations
BioGrid:12566eggNOG:ENOG410XQV9eggNOG:KOG0285EMBL:AL161542EMBL:CP002687EMBL:X82824EMBL:X82825
EMBL:Z97339EnsemblPlants:AT4G15900EnsemblPlants:AT4G15900.1entrez:827272ExpressionAtlas:Q42384Gene3D:2.130.10.10GeneID:827272
Genevisible:Q42384GO:GO:0000398GO:GO:0000974GO:GO:0005634GO:GO:0006508GO:GO:0009749GO:GO:0009755
GO:GO:0009870GO:GO:0010154GO:GO:0010182GO:GO:0010204GO:GO:0016567GO:GO:0042742GO:GO:0045087
GO:GO:0045892GO:GO:0048364GO:GO:0048366GO:GO:0048825GO:GO:0050832GO:GO:0071011GO:GO:0071013
GO:GO:0080008Gramene:AT4G15900.1hmmpanther:PTHR19923hmmpanther:PTHR19923:SF0HOGENOM:HOG000207595InParanoid:Q42384IntAct:Q42384
InterPro:IPR001680InterPro:IPR015943InterPro:IPR017986InterPro:IPR019775InterPro:IPR020472KEGG:ath:AT4G15900KO:K12862
MINT:MINT-8070047OMA:LHKTTRTPaxDb:Q42384Pfam:PF00400Pfam:Q42384Pfscan:PS50082Pfscan:PS50294
PhylomeDB:Q42384PIR:S49820PRIDE:Q42384PRINTS:PR00320PRO:PR:Q42384PROSITE:PS00678PROSITE:PS50082
PROSITE:PS50294ProteinModelPortal:Q42384Proteomes:UP000006548Reactome:R-ATH-72163RefSeq:NP_193325.1scanprosite:PS00678SMART:SM00320
SMR:Q42384STRING:3702.AT4G15900.1SUPFAM:SSF50978TAIR:AT4G15900tair10-symbols:PRL1UniGene:At.103UniPathway:UPA00143
UniProt:Q08A56UniProt:Q42384
Coordinates (TAIR10) chr4:+:9023775..9027443
Molecular Weight (calculated) 54012.40 Da
IEP (calculated) 9.30
GRAVY (calculated) -0.45
Length 486 amino acids
Sequence (TAIR10)
(BLAST)
001: MPAPTTEIEP IEAQSLKKLS LKSLKRSLEL FSPVHGQFPP PDPEAKQIRL SHKMKVAFGG VEPVVSQPPR QPDRINEQPG PSNALSLAAP EGSKSTQKGA
101: TESAIVVGPT LLRPILPKGL NYTGSSGKST TIIPANVSSY QRNLSTAALM ERIPSRWPRP EWHAPWKNYR VIQGHLGWVR SVAFDPSNEW FCTGSADRTI
201: KIWDVATGVL KLTLTGHIEQ VRGLAVSNRH TYMFSAGDDK QVKCWDLEQN KVIRSYHGHL SGVYCLALHP TLDVLLTGGR DSVCRVWDIR TKMQIFALSG
301: HDNTVCSVFT RPTDPQVVTG SHDTTIKFWD LRYGKTMSTL THHKKSVRAM TLHPKENAFA SASADNTKKF SLPKGEFCHN MLSQQKTIIN AMAVNEDGVM
401: VTGGDNGSIW FWDWKSGHSF QQSETIVQPG SLESEAGIYA ACYDNTGSRL VTCEADKTIK MWKEDENATP ETHPINFKPP KEIRRF
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)