suba logo
AT4G14220.1
Subcellular Consensus
(Prediction and Experimental)

min: heatmap :max

.
SUBAcon:
nucleus 1.000
What is SUBAcon?
What is ASURE?
SUBAcon computations
Experimental Localisations and PPI
FP MS/MS PPI
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no PPI data
Description (TAIR10) protein_coding : RING-H2 group F1A
Curator
Summary (TAIR10)
encodes a RING-type E3 ubiquitin ligase implicated in gametogenesis. RHF1a can interact with the cell cycle inhibitor ICK4/KRP6 in vitro. It apppears to target ICK4KRP6 for degradation following meiosis in order to allow the mitoses associated with megagametogenesis and microgametogenesis to occur. RHF1a is expressed in the carpels throughout floral development. It is expressed in various tissues of the anthers during the early stages of anther development but not in stage 12 flowers and beyond.
Computational
Description (TAIR10)
RING-H2 group F1A (RHF1A); FUNCTIONS IN: ubiquitin-protein ligase activity, zinc ion binding; INVOLVED IN: regulation of cell cycle, proteasomal protein catabolic process, megagametogenesis, microgametogenesis; LOCATED IN: membrane; EXPRESSED IN: 27 plant structures; EXPRESSED DURING: 12 growth stages; CONTAINS InterPro DOMAIN/s: Zinc finger, RING-type (InterPro:IPR001841), Zinc finger, C3HC4 RING-type (InterPro:IPR018957); BEST Arabidopsis thaliana protein match is: RING-H2 group F2A (TAIR:AT5G22000.3); Has 5179 Blast hits to 4938 proteins in 253 species: Archae - 0; Bacteria - 16; Metazoa - 1752; Fungi - 320; Plants - 2058; Viruses - 9; Other Eukaryotes - 1024 (source: NCBI BLink).
Protein Annotations
BioGrid:12359EC:6.3.2.-eggNOG:ENOG41121N2eggNOG:KOG0800EMBL:AK117968EMBL:AL161538EMBL:CP002687
EMBL:DQ059122EMBL:Z97335EnsemblPlants:AT4G14220EnsemblPlants:AT4G14220.1entrez:827062Gene3D:3.30.40.10GeneID:827062
Genevisible:Q4TU14GO:GO:0000209GO:GO:0004842GO:GO:0008270GO:GO:0009561GO:GO:0010498GO:GO:0016020
GO:GO:0016567GO:GO:0016874GO:GO:0042787GO:GO:0043161GO:GO:0051726GO:GO:0055046GO:GO:0061630
Gramene:AT4G14220.1hmmpanther:PTHR22763hmmpanther:PTHR22763:SF65HOGENOM:HOG000070813InParanoid:Q4TU14InterPro:IPR001841InterPro:IPR013083
iPTMnet:Q4TU14KEGG:ath:AT4G14220KO:K19043OMA:AISHVEHPaxDb:Q4TU14Pfam:PF13639Pfam:Q4TU14
Pfscan:PS50089PhylomeDB:Q4TU14PIR:C85155PRIDE:Q4TU14PRO:PR:Q4TU14PROSITE:PS50089ProteinModelPortal:Q4TU14
Proteomes:UP000006548RefSeq:NP_193158.2SMART:SM00184SMR:Q4TU14STRING:3702.AT4G14220.1SUPFAM:SSF57850TAIR:AT4G14220
tair10-symbols:RHF1AUniGene:At.24002UniPathway:UPA00143UniProt:Q4TU14
Coordinates (TAIR10) chr4:+:8196012..8198240
Molecular Weight (calculated) 40285.60 Da
IEP (calculated) 7.34
GRAVY (calculated) -0.64
Length 371 amino acids
Sequence (TAIR10)
(BLAST)
001: MSNFTYTSAF NLSDNSPFNP AIGSSSSSSS ALVVASDDDN NTDDACSICL EPFTLQDPST VTSCKHEYHL QCIIEWSQRS KECPICWQLF VLRDPASQEL
101: LAAVEKERLL KTRNISSSSP ISIHHSHDDF HSEEEESQFS SFDEQFLRHL TEAAHRRCLL RRRDGQISSS LVSSSDPTTI HPTDLVNLYR LSAISHVEHQ
201: NSNPCPSPGS MTPSPVSGHS SIPADSNNGS RISPGPSPSR SSQSPKSPEA SSLPEAIKSK LAAASAKYKE SISKSKQGLK EKLLARNNSV KELSKGVQRE
301: MNAGIAGVAR MIERMDFSSK RFGGSAHVST STATASGFNF SFKGKRVEAN SKSNNNGDKT EPQKLQGGET C
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)