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AT4G13940.1
Subcellular Consensus
(Prediction and Experimental)
min: heatmap :max

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SUBAcon:
cytosol 1.000
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
  • PMID:31975158 (2020): plastid
  • PMID:31871212 (2020): mitochondrion
  • PMID:31615849 (2019): plastid plastid thylakoid
  • PMID:31541795 (2020): plasma membrane
  • PMID:31520498 (2020): mitochondrion
  • PMID:31186290 (2019): cytosol None
  • PMID:30962257 (2019): plastid
  • PMID:30865669 (2019): plastid
  • PMID:30783145 (2019): extracellular region plant-type cell wall
  • PMID:30447334 (2019): plasma membrane
  • PMID:29104584 (2017): nucleus nuclear matrix nucleolus
  • PMID:28865150 (2017): extracellular region plant-type cell wall
  • PMID:27943495 (2017): mitochondrion
  • PMID:26781341 (2016): plasma membrane
  • PMID:26572690 (2016): extracellular region plant-type cell wall
  • PMID:25900983 (2015): plant-type vacuole plant-type vacuole membrane
  • PMID:25900983 (2015): Golgi
  • PMID:25900983 (2015): Golgi Golgi apparatus Golgi membrane
  • PMID:25900983 (2015): Golgi trans-Golgi network multivesicular body
  • PMID:25900983 (2015): Golgi trans-Golgi network early endosome
  • PMID:25900983 (2015): Golgi trans-Golgi network
  • PMID:25852701 (2015): extracellular region apoplast
  • PMID:25641898 (2015): plasma membrane
  • PMID:24361574 (2014): plastid plastid stroma
  • PMID:24124904 (2013): plastid
  • PMID:24012629 (2013): nucleus
  • PMID:23903016 (2013): plant-type vacuole plant-type vacuole membrane
  • PMID:23673981 (2013): plastid plastid stroma plastoglobules
  • PMID:23396599 (2013): nucleus nuclear envelope nuclear inner membrane
  • PMID:22574745 (2012): mitochondrion
  • PMID:22550958 (2012): plastid
  • PMID:22318864 (2012): plasma membrane
  • PMID:22215637 (2012): plasma membrane
  • PMID:21988472 (2012): plant-type vacuole plant-type vacuole membrane
  • PMID:21533090 (2011): extracellular region plant-type cell wall
  • PMID:21433285 (2011): plasma membrane
  • PMID:21166475 (2011): cytosol
  • PMID:20061580 (2010): plastid
  • PMID:19334764 (2009): plasma membrane
  • PMID:17644812 (2007): plasma membrane
  • PMID:17151019 (2007): plant-type vacuole
  • PMID:15215502 (2004): plant-type vacuole
SUBAcon links
AGI-AGI relationships
Coexpression PPI
Description (TAIR10) protein_coding : S-adenosyl-L-homocysteine hydrolase
Curator
Summary (TAIR10)
Encodes a S-adenosyl-L-homocysteine hydrolase required for DNA methylation-dependent gene silencing.
Computational
Description (TAIR10)
MATERNAL EFFECT EMBRYO ARREST 58 (MEE58); FUNCTIONS IN: adenosylhomocysteinase activity, copper ion binding; INVOLVED IN: methylation-dependent chromatin silencing, one-carbon metabolic process, posttranscriptional gene silencing, embryo development ending in seed dormancy; LOCATED IN: plasma membrane, vacuole, membrane; EXPRESSED IN: 36 plant structures; EXPRESSED DURING: 16 growth stages; CONTAINS InterPro DOMAIN/s: S-adenosyl-L-homocysteine hydrolase, conserved site (InterPro:IPR020082), S-adenosyl-L-homocysteine hydrolase (InterPro:IPR000043), S-adenosyl-L-homocysteine hydrolase, NAD binding (InterPro:IPR015878); BEST Arabidopsis thaliana protein match is: S-adenosyl-l-homocysteine (SAH) hydrolase 2 (TAIR:AT3G23810.1); Has 7964 Blast hits to 7958 proteins in 1477 species: Archae - 229; Bacteria - 2334; Metazoa - 639; Fungi - 145; Plants - 247; Viruses - 0; Other Eukaryotes - 4370 (source: NCBI BLink).
Protein Annotations
BioCyc:ARA:AT4G13940-MONOMERBioCyc:ARA:GQT-1327-MONOMERBioCyc:ARA:GQT-1328-MONOMERBioCyc:ARA:GQT-1329-MONOMER
BioGrid:12325EC:3.3.1.1eggNOG:COG0499eggNOG:KOG1370
EMBL:AF059581EMBL:AF325037EMBL:AL161537EMBL:AY042866
EMBL:AY049279EMBL:AY081468EMBL:AY085669EMBL:AY090284
EMBL:BT002404EMBL:CP002687EMBL:Z97059EMBL:Z97335
EnsemblPlants:AT4G13940EnsemblPlants:AT4G13940.1entrez:827028ExpressionAtlas:O23255
Gene3D:3.40.50.720GeneID:827028Genevisible:O23255GO:GO:0004013
GO:GO:0005507GO:GO:0005773GO:GO:0005774GO:GO:0005829
GO:GO:0005886GO:GO:0006346GO:GO:0006730GO:GO:0009506
GO:GO:0009793GO:GO:0016020GO:GO:0016441GO:GO:0033353
GO:GO:0048046gramene_pathway:3.3.1.1gramene_pathway:PWY-5041gramene_plant_reactome:1119501
gramene_plant_reactome:6876108HAMAP:MF_00563hmmpanther:PTHR23420HOGENOM:HOG000227986
InParanoid:O23255IntAct:O23255InterPro:IPR000043InterPro:IPR015878
InterPro:IPR016040InterPro:IPR020082KEGG:00270+3.3.1.1OMA:NLVHERF
PANTHER:PTHR23420PaxDb:O23255Pfam:O23255Pfam:PF00670
Pfam:PF05221PhylomeDB:O23255PIR:C71400PIRSF:PIRSF001109
PRIDE:O23255PRO:PR:O23255PROSITE:PS00738PROSITE:PS00739
ProteinModelPortal:O23255Proteomes:UP000006548Reactome:R-ATH-156581Reactome:R-ATH-1614635
RefSeq:NP_193130.1scanprosite:PS00738scanprosite:PS00739SMART:SM00996
SMART:SM00997SMR:O23255STRING:3702.AT4G13940.1SUPFAM:SSF51735
SUPFAM:SSF52283TAIR:AT4G13940tair10-symbols:ATSAHH1tair10-symbols:EMB1395
tair10-symbols:HOG1tair10-symbols:MEE58tair10-symbols:SAHH1TIGRfam:TIGR00936
TIGRFAMs:TIGR00936UniGene:At.24056UniGene:At.24845UniGene:At.71956
UniGene:At.74987UniGene:At.74988UniPathway:UPA00314UniProt:O23255
Coordinates (TAIR10) chr4:+:8054931..8056676
Molecular Weight (calculated) 53381.60 Da
IEP (calculated) 5.83
GRAVY (calculated) -0.13
Length 485 amino acids
Sequence (TAIR10)
(BLAST)
001: MALLVEKTSS GREYKVKDMS QADFGRLELE LAEVEMPGLM ACRTEFGPSQ PFKGARITGS LHMTIQTAVL IETLTALGAE VRWCSCNIFS TQDHAAAAIA
101: RDSAAVFAWK GETLQEYWWC TERALDWGPG GGPDLIVDDG GDATLLIHEG VKAEEIFEKT GQVPDPTSTD NPEFQIVLSI IKEGLQVDPK KYHKMKERLV
201: GVSEETTTGV KRLYQMQQNG TLLFPAINVN DSVTKSKFDN LYGCRHSLPD GLMRATDVMI AGKVAVICGY GDVGKGCAAA MKTAGARVIV TEIDPICALQ
301: ALMEGLQVLT LEDVVSEADI FVTTTGNKDI IMVDHMRKMK NNAIVCNIGH FDNEIDMLGL ETYPGVKRIT IKPQTDRWVF PETKAGIIVL AEGRLMNLGC
401: ATGHPSFVMS CSFTNQVIAQ LELWNEKASG KYEKKVYVLP KHLDEKVALL HLGKLGARLT KLSKDQSDYV SIPIEGPYKP PHYRY
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)