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AT4G11820.1
Subcellular Consensus
(Prediction and Experimental)
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SUBAcon:
cytosol 1.000
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
  • PMID:28865150 (2017): extracellular region plant-type cell wall
  • PMID:26572690 (2016): extracellular region plant-type cell wall
  • PMID:21166475 (2011): cytosol
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no PPI data
Description (TAIR10) protein_coding : hydroxymethylglutaryl-CoA synthase / HMG-CoA synthase / 3-hydroxy-3-methylglutaryl coenzyme A synthase
Curator
Summary (TAIR10)
Encodes a protein with hydroxymethylglutaryl-CoA synthase activity which was characterized by phenotypical complementation of the S. cerevisiae mutant.
Computational
Description (TAIR10)
HYDROXYMETHYLGLUTARYL-COA SYNTHASE (HMGS); CONTAINS InterPro DOMAIN/s: Hydroxymethylglutaryl-coenzyme A synthase C-terminal (InterPro:IPR013746), Thiolase-like (InterPro:IPR016039), Hydroxymethylglutaryl-coenzyme A synthase, N-terminal (InterPro:IPR013528), Hydroxymethylglutaryl-CoA synthase, eukaryotic (InterPro:IPR010122), Hydroxymethylglutaryl-coenzyme A synthase, active site (InterPro:IPR000590); Has 2141 Blast hits to 2138 proteins in 847 species: Archae - 222; Bacteria - 1037; Metazoa - 301; Fungi - 182; Plants - 116; Viruses - 0; Other Eukaryotes - 283 (source: NCBI BLink).
Protein Annotations
EnsemblPlants:AT4G11820EnsemblPlants:AT4G11820.1entrez:826788gramene_pathway:2.3.3.10
gramene_pathway:PWY-922gramene_plant_reactome:1119615gramene_plant_reactome:6875083hmmpanther:PTHR11877
hmmpanther:PTHR11877:SF20KEGG:00072+2.3.3.10KEGG:00280+2.3.3.10KEGG:00650+2.3.3.10
KEGG:00900+2.3.3.10Pfam:PF01154Pfam:PF08540scanprosite:PS01226
tair10-symbols:EMB2778tair10-symbols:FKP1tair10-symbols:HMGStair10-symbols:MVA1
TIGRfam:TIGR01833unipathway:UPA00058
Coordinates (TAIR10) chr4:-:7109124..7111213
Molecular Weight (calculated) 45207.80 Da
IEP (calculated) 7.23
GRAVY (calculated) -0.29
Length 406 amino acids
Sequence (TAIR10)
(BLAST)
001: MSFNAVTSLF EKYKIDPNQI GRLEVGSETV IDKSKSIKTF LMQLFEKCGN TDVEGVDSTN ACYGGTAALL NCVNWVESNS WDGRYGLVIC TDSAVYAEGP
101: ARPTGGAAAI AMLIGPDAPI VFESKLRASH MAHVYDFYKP NLASEYPVVD GKLSQTCYLM ALDSCYKHLC NKFEKIEGKE FSINDADYIV FHSPYNKLVQ
201: KSFARLLYND FLRNASSIDE AAKEKFTPYS SLTLDESYQS RDLEKVSQQI AKPFYDAKVQ PTTLIPKEVG NMYTASLYAA FASLIHKKHN DLAGKRVVMF
301: SYGSGSTATM FSLRLNDNKP PFSISNIASV MDVGGKLKAR HEYAPEKFVE TMKLMEHRYG AKDFVTTKEG IIDLLAPGTY YLKEVDSLYR RFYGKKGEDG
401: SVANGH
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)