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AT4G11110.1
Subcellular Consensus
(Prediction and Experimental)

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SUBAcon:
nucleus 1.000
What is SUBAcon?
What is ASURE?
SUBAcon computations
Experimental Localisations and PPI
FP MS/MS PPI
SUBAcon links
AGI-AGI relationships
Coexpression PPI
Description (TAIR10) protein_coding : SPA1-related 2
Curator
Summary (TAIR10)
Encodes a member of the SPA (suppressor of phyA-105) protein family (SPA1-SPA4). SPA proteins contain an N-terminal serine/threonine kinase-like motif followed by a coiled-coil structure and a C-terminal WD-repeat domain. SPA proteins function redundantly in suppressing photomorphogenesis in dark- and light-grown seedlings. SPA2 primarily regulates seedling development in darkness and has little function in light-grown seedlings or adult plants.
Computational
Description (TAIR10)
SPA1-related 2 (SPA2); FUNCTIONS IN: protein binding, signal transducer activity; INVOLVED IN: protein amino acid phosphorylation; LOCATED IN: CUL4 RING ubiquitin ligase complex, heterotrimeric G-protein complex; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: WD40 repeat 2 (InterPro:IPR019782), WD40 repeat, conserved site (InterPro:IPR019775), WD40 repeat (InterPro:IPR001680), Serine/threonine-protein kinase-like domain (InterPro:IPR017442), Protein kinase-like domain (InterPro:IPR011009), G-protein beta WD-40 repeat, region (InterPro:IPR020472), WD40 repeat-like-containing domain (InterPro:IPR011046), Protein kinase, catalytic domain (InterPro:IPR000719), WD40-repeat-containing domain (InterPro:IPR017986), WD40/YVTN repeat-like-containing domain (InterPro:IPR015943), WD40 repeat, subgroup (InterPro:IPR019781); BEST Arabidopsis thaliana protein match is: SPA (suppressor of phyA-105) protein family (TAIR:AT2G46340.1); Has 34047 Blast hits to 20982 proteins in 883 species: Archae - 38; Bacteria - 5461; Metazoa - 12841; Fungi - 7307; Plants - 4015; Viruses - 10; Other Eukaryotes - 4375 (source: NCBI BLink).
Protein Annotations
BioGrid:12011eggNOG:ENOG410XS0BeggNOG:KOG1033EMBL:AF080120EMBL:AK229182EMBL:AL049876EMBL:AL161531
EMBL:CP002687EnsemblPlants:AT4G11110EnsemblPlants:AT4G11110.1entrez:826712Gene3D:2.130.10.10GeneID:826712Genevisible:Q9T014
GO:GO:0004672GO:GO:0005524GO:GO:0005634GO:GO:0009585GO:GO:0080008Gramene:AT4G11110.1hmmpanther:PTHR22847
hmmpanther:PTHR22847:SF443HOGENOM:HOG000029775InParanoid:Q9T014IntAct:Q9T014InterPro:IPR000719InterPro:IPR001680InterPro:IPR011009
InterPro:IPR015943InterPro:IPR017986InterPro:IPR019775InterPro:IPR020472iPTMnet:Q9T014KEGG:ath:AT4G11110ncoils:Coil
OMA:VENSETWPaxDb:Q9T014Pfam:PF00069Pfam:PF00400Pfam:Q9T014Pfscan:PS50011Pfscan:PS50082
Pfscan:PS50294PhylomeDB:Q9T014PIR:T01922PIR:T01923PIR:T08190PRIDE:Q9T014PRINTS:PR00320
PRO:PR:Q9T014PROSITE:PS00678PROSITE:PS50011PROSITE:PS50082PROSITE:PS50294ProteinModelPortal:Q9T014Proteomes:UP000006548
Reactome:R-ATH-349425RefSeq:NP_192849.4scanprosite:PS00678SMART:SM00320SMR:Q9T014STRING:3702.AT4G11110.1SUPFAM:SSF50978
SUPFAM:SSF56112TAIR:AT4G11110tair10-symbols:SPA2UniGene:At.46392UniProt:Q9T014
Coordinates (TAIR10) chr4:+:6772163..6776675
Molecular Weight (calculated) 115012.00 Da
IEP (calculated) 5.98
GRAVY (calculated) -0.46
Length 1036 amino acids
Sequence (TAIR10)
(BLAST)
0001: MMDEGSVGDV SRIDEADVAH LQFKNSEQSF KPENIEVREV KEVQVQREAG SPDCSYGVIA DFLDGKNGGD HVELIGNEPC SSRQNTNDEG DVVEELTVKT
0101: CEGSSMAIVG RPSSRARLEM NRSQFLHRFP LDGDLPGSSS MSKKVIDRGT VSILRNAGKM SLPETSNGQL AIIAVNGEAN EHLTNVERNP VPVEALSHEG
0201: IKTKMLSQSG FSQFFVRKTL KGKGVTFRGP PNNRSKARNM DQQTVASSGS ALVIANTSAK ISSSIPLAAY DGLPCLPSNT SKPSSCANPS DTHRGCGGEG
0301: LSLREWLKSE RQEVNKAECM YIFRQIVDHV DCSHSQGVVL CDLRPSSFKI FKENAVKYVV SGSQRESFDS NMNKETLSQL ENPLVRRRLG DTSSLSIPAK
0401: KQKSSGPSSR QWPMFQRAGG VNIQTENNDG AIQEFHFRSS QPHCSTVACP FTSVSEQLEE KWYASPEELR GDMRSASSNI YSLGILLYEL LSQFQCERAR
0501: EAAMSDIRHR ILPPKFLSEN PKEAGFCLWL LHPESSCRPS TRDILQSEVV NGIPDLYAEG LSLSIEQEDT ESELLQHFLF LSQEKRQKHA GNLMEEIASV
0601: EADIEEIVKR RCAIGPPSLE EASSSSPASS VPEMRLIRNI NQLESAYFAA RIDAHLPEAR YRLRPDRDLL RNSDNTVAEV ENSETWSSDD RVGAFFDGLC
0701: KYARYSKFET RGVLRTSELN NTSNVICSLG FDRDEDYFAT AGVSKKIKIY EFNSLFNESV DIHYPAIEMP NRSKLSGVCW NNYIRNYLAS SDYDGIVKLW
0801: DVTTGQAISH FIEHEKRAWS VDFSEACPTK LASGSDDCSV KLWNINERNC LGTIRNIANV CCVQFSPQSS HLLAFGSSDF RTYCYDLRNL RTPWCILSGH
0901: NKAVSYAKFL DNETLVTAST DNTLKLWDLK KTTHGGLSTN ACSLTFGGHT NEKNFVGLST SDGYIACGSE TNEVYAYHRS LPMPITSYKF GSIDPISGKE
1001: IEEDNNLFVS SVCWRKRSNM VVSASSNGSI KVLQLV
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)