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AT4G08920.1
Subcellular Consensus
(Prediction and Experimental)

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SUBAcon:
cytosol 0.500
nucleus 0.500
ASURE: cytosol,nucleus
What is SUBAcon?
What is ASURE?
SUBAcon computations
Experimental Localisations and PPI
FP MS/MS PPI
SUBAcon links
AGI-AGI relationships
Coexpression PPI
Description (TAIR10) protein_coding : cryptochrome 1
Curator
Summary (TAIR10)
Encodes CRY1, a flavin-type blue-light photoreceptor with ATP binding and autophosphorylation activity. Functions in perception of blue / green ratio of light. The photoreceptor may be involved in electron transport. Mutant phenotype displays a blue light-dependent inhibition of hypocotyl elongation. Photoreceptor activity requires light-induced homodimerisation of the N-terminal CNT1 domains of CRY1. Involved in blue-light induced stomatal opening. The C-terminal domain of the protein undergoes a light dependent conformational change. Also involved in response to circadian rhythm. Mutants exhibit long hypocotyl under blue light and are out of phase in their response to circadian rhythm. CRY1 is present in the nucleus and cytoplasm. Different subcellular pools of CRY1 have different functions during photomorphogenesis of Arabidopsis seedlings.
Computational
Description (TAIR10)
cryptochrome 1 (CRY1); CONTAINS InterPro DOMAIN/s: Rossmann-like alpha/beta/alpha sandwich fold (InterPro:IPR014729), Cryptochrome/DNA photolyase, class 1 conserved site, C-terminal (InterPro:IPR018394), DNA photolyase, N-terminal (InterPro:IPR006050), Cryptochrome C-terminal (InterPro:IPR020978), DNA photolyase, FAD-binding/Cryptochrome, C-terminal (InterPro:IPR005101), Cryptochrome, plant (InterPro:IPR014134), Cryptochrome/DNA photolyase, class 1 (InterPro:IPR002081); BEST Arabidopsis thaliana protein match is: cryptochrome 2 (TAIR:AT1G04400.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).
Protein Annotations
BioCyc:ARA:GQT-2162-MONOMERBioGrid:11769DisProt:DP00474eggNOG:COG0415eggNOG:KOG0133EMBL:AF128396EMBL:AF361588
EMBL:AL161513EMBL:AY124863EMBL:CP002687EMBL:S66907EMBL:S66909EnsemblPlants:AT4G08920EnsemblPlants:AT4G08920.1
entrez:826470EvolutionaryTrace:Q43125Gene3D:3.40.50.620GeneID:826470Genevisible:Q43125GO:GO:0004672GO:GO:0005524
GO:GO:0005634GO:GO:0005737GO:GO:0006915GO:GO:0006952GO:GO:0007623GO:GO:0009414GO:GO:0009416
GO:GO:0009583GO:GO:0009637GO:GO:0009638GO:GO:0009640GO:GO:0009644GO:GO:0009646GO:GO:0009785
GO:GO:0009882GO:GO:0010075GO:GO:0010114GO:GO:0010117GO:GO:0010118GO:GO:0010218GO:GO:0010244
GO:GO:0010310GO:GO:0010343GO:GO:0010617GO:GO:0016301GO:GO:0016604GO:GO:0018298GO:GO:0042752
GO:GO:0042802GO:GO:0046283GO:GO:0046777GO:GO:0046872GO:GO:0051510GO:GO:0055114GO:GO:0060918
GO:GO:0071000GO:GO:0071949GO:GO:0072387GO:GO:0099402GO:GO:1900426GO:GO:1901332GO:GO:1901371
GO:GO:1901529GO:GO:1901672GO:GO:1902347GO:GO:1902448GO:GO:2000377Gramene:AT4G08920.1hmmpanther:PTHR11455
hmmpanther:PTHR11455:SF24HOGENOM:HOG000245621InParanoid:Q43125IntAct:Q43125InterPro:IPR002081InterPro:IPR005101InterPro:IPR006050
InterPro:IPR014134InterPro:IPR014729InterPro:IPR018394InterPro:IPR020978iPTMnet:Q43125KEGG:ath:AT4G08920KO:K12118
MINT:MINT-192438ncoils:CoilOMA:QFPSEENPaxDb:Q43125PDB:1U3CPDB:1U3DPDBsum:1U3C
PDBsum:1U3DPfam:PF00875Pfam:PF03441Pfam:PF12546Pfam:Q43125Pfscan:PS51645PIR:H85089
PIR:S39058PRIDE:Q43125PRINTS:PR00147PRO:PR:Q43125PROSITE:PS00394PROSITE:PS00691PROSITE:PS51645
ProteinModelPortal:Q43125Proteomes:UP000006548RefSeq:NP_567341.1scanprosite:PS00394scanprosite:PS00691SMR:Q43125STRING:3702.AT4G08920.1
SUPFAM:SSF48173SUPFAM:SSF52425TAIR:AT4G08920tair10-symbols:ATCRY1tair10-symbols:BLU1tair10-symbols:CRY1tair10-symbols:HY4
tair10-symbols:OOP2TIGRfam:TIGR02766TIGRFAMs:TIGR02766UniGene:At.27730UniProt:Q43125
Coordinates (TAIR10) chr4:+:5724260..5726905
Molecular Weight (calculated) 76698.70 Da
IEP (calculated) 5.03
GRAVY (calculated) -0.47
Length 681 amino acids
Sequence (TAIR10)
(BLAST)
001: MSGSVSGCGS GGCSIVWFRR DLRVEDNPAL AAAVRAGPVI ALFVWAPEEE GHYHPGRVSR WWLKNSLAQL DSSLRSLGTC LITKRSTDSV ASLLDVVKST
101: GASQIFFNHL YDPLSLVRDH RAKDVLTAQG IAVRSFNADL LYEPWEVTDE LGRPFSMFAA FWERCLSMPY DPESPLLPPK KIISGDVSKC VADPLVFEDD
201: SEKGSNALLA RAWSPGWSNG DKALTTFING PLLEYSKNRR KADSATTSFL SPHLHFGEVS VRKVFHLVRI KQVAWANEGN EAGEESVNLF LKSIGLREYS
301: RYISFNHPYS HERPLLGHLK FFPWAVDENY FKAWRQGRTG YPLVDAGMRE LWATGWLHDR IRVVVSSFFV KVLQLPWRWG MKYFWDTLLD ADLESDALGW
401: QYITGTLPDS REFDRIDNPQ FEGYKFDPNG EYVRRWLPEL SRLPTDWIHH PWNAPESVLQ AAGIELGSNY PLPIVGLDEA KARLHEALSQ MWQLEAASRA
501: AIENGSEEGL GDSAEVEEAP IEFPRDITME ETEPTRLNPN RRYEDQMVPS ITSSLIRPEE DEESSLNLRN SVGDSRAEVP RNMVNTNQAQ QRRAEPASNQ
601: VTAMIPEFNI RIVAESTEDS TAESSSSGRR ERSGGIVPEW SPGYSEQFPS EENGIGGGST TSSYLQNHHE ILNWRRLSQT G
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)