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AT4G02060.1
Subcellular Consensus
(Prediction and Experimental)

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SUBAcon:
nucleus 1.000
ASURE: nucleus
What is SUBAcon?
What is ASURE?
SUBAcon computations
Experimental Localisations and PPI
FP MS/MS PPI
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no PPI data
Description (TAIR10) protein_coding : Minichromosome maintenance (MCM2/3/5) family protein
Curator
Summary (TAIR10)
Member of the minichromosome maintenance complex, involved in DNA replication initiation. Abundant in proliferating and endocycling tissues. Localized in the nucleus during G1, S and G2 phases of the cell cycle, and are released into the cytoplasmic compartment during mitosis. Binds chromatin.
Computational
Description (TAIR10)
PROLIFERA (PRL); FUNCTIONS IN: protein binding, DNA-dependent ATPase activity, DNA binding, ATP binding; INVOLVED IN: sugar mediated signaling pathway, cell proliferation, DNA-dependent DNA replication initiation, DNA unwinding involved in replication; LOCATED IN: nuclear chromatin, nucleus, cytoplasm; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 16 growth stages; CONTAINS InterPro DOMAIN/s: Nucleic acid-binding, OB-fold-like (InterPro:IPR016027), Nucleic acid-binding, OB-fold (InterPro:IPR012340), ATPase, AAA+ type, core (InterPro:IPR003593), DNA-dependent ATPase MCM (InterPro:IPR001208), DNA-dependent ATPase MCM, conserved site (InterPro:IPR018525), MCM protein 7 (InterPro:IPR008050); BEST Arabidopsis thaliana protein match is: minichromosome maintenance (MCM2/3/5) family protein (TAIR:AT5G44635.1); Has 4609 Blast hits to 4442 proteins in 796 species: Archae - 407; Bacteria - 660; Metazoa - 1239; Fungi - 945; Plants - 433; Viruses - 2; Other Eukaryotes - 923 (source: NCBI BLink).
Protein Annotations
BioGrid:13442EC:3.6.4.12eggNOG:COG1241eggNOG:KOG0482EMBL:AF001308EMBL:AF001535EMBL:AL161493
EMBL:CP002687EMBL:L39954EnsemblPlants:AT4G02060EnsemblPlants:AT4G02060.1EnsemblPlants:AT4G02060.2entrez:828153Gene3D:2.40.50.140
Gene3D:3.40.50.300GeneID:828153Genevisible:P43299GO:GO:0000347GO:GO:0003677GO:GO:0003678GO:GO:0005524
GO:GO:0005634GO:GO:0005737GO:GO:0006268GO:GO:0006270GO:GO:0006351GO:GO:0006355GO:GO:0007049
GO:GO:0010182GO:GO:0042555GO:GO:0046872Gramene:AT4G02060.1Gramene:AT4G02060.2hmmpanther:PTHR11630hmmpanther:PTHR11630:SF26
HOGENOM:HOG000224125InParanoid:P43299IntAct:P43299InterPro:IPR001208InterPro:IPR008050InterPro:IPR012340InterPro:IPR018525
InterPro:IPR027417InterPro:IPR027925InterPro:IPR031327iPTMnet:P43299KEGG:ath:AT4G02060KO:K02210MINT:MINT-6799339
OMA:QTRACRFPANTHER:PTHR11630:SF26PaxDb:P43299Pfam:P43299Pfam:PF00493Pfam:PF14551Pfscan:PS50051
PhylomeDB:P43299PIR:T01507PRIDE:P43299PRINTS:PR01657PRINTS:PR01663PRO:PR:P43299PROSITE:PS00847
PROSITE:PS50051ProteinModelPortal:P43299Proteomes:UP000006548Reactome:R-ATH-68867Reactome:R-ATH-68949Reactome:R-ATH-68962Reactome:R-ATH-69052
Reactome:R-ATH-69300RefSeq:NP_001190655.1RefSeq:NP_192115.1scanprosite:PS00847SMART:SM00350SMR:P43299STRING:3702.AT4G02060.1
SUPFAM:SSF50249SUPFAM:SSF52540TAIR:AT4G02060tair10-symbols:MCM7tair10-symbols:PRLUniGene:At.3861UniProt:P43299
Coordinates (TAIR10) chr4:+:901484..905297
Molecular Weight (calculated) 80337.80 Da
IEP (calculated) 5.84
GRAVY (calculated) -0.34
Length 716 amino acids
Sequence (TAIR10)
(BLAST)
001: MKDHDFDGDK GLAKGFLENF ADANGRSKYM EILQEVSNRK IRAIQVDLDD LFNYKDESEE FLGRLTENTR RYVSIFSAAV DELLPEPTEA FPDDDHDILM
101: TQRADDGTDN PDVSDPHQQI PSEIKRYYEV YFKAPSKGRP STIREVKASH IGQLVRISGI VTRCSDVKPL MAVAVYTCED CGHEIYQEVT SRVFMPLFKC
201: PSSRCRLNSK AGNPILQLRA SKFLKFQEAK MQELAEHVPK GHIPRSMTVH LRGELTRKVS PGDVVEFSGI FLPIPYTGFK ALRAGLVADT YLEATSVTHF
301: KKKYEEYEFQ KDEEEQIARL AEDGDIYNKL SRSLAPEIYG HEDIKKALLL LLVGAPHRQL KDGMKIRGDV HICLMGDPGV AKSQLLKHII NVAPRGVYTT
401: GKGSSGVGLT AAVMRDQVTN EMVLEGGALV LADMGICAID EFDKMDESDR TAIHEVMEQQ TVSIAKAGIT TSLNARTAVL AAANPAWGRY DLRRTPAENI
501: NLPPALLSRF DLLWLILDRA DMDSDLELAK HVLHVHQTEE SPALGFEPLE PNILRAYISA ARRLSPYVPA ELEEYIATAY SSIRQEEAKS NTPHSYTTVR
601: TLLSILRISA ALARLRFSES VAQSDVDEAL RLMQMSKISL YADDRQKAGL DAISDTYSII RDEAARSKKT HVSYANALNW ISRKGYSEAQ LKECLEEYAA
701: LNVWQIDPHT FDIRFI
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)