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AT4G00450.1
Subcellular Consensus
(Prediction and Experimental)

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SUBAcon:
plasma membrane 0.883
What is SUBAcon?
What is ASURE?
SUBAcon computations
Experimental Localisations and PPI
FP MS/MS PPI
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no PPI data
Description (TAIR10) protein_coding : RNA polymerase II transcription mediators
Curator
Summary (TAIR10)
Encodes the Arabidopsis homolog of the transcriptional regulator MED12, is dynamically expressed during embryogenesis and regulates both developmental timing and the radial pattern formation. Involved in flowering time. The mutant enhances the expression of the flowering time (FT) gene. A knockout mutant of this gene showed late-flowering phenotype.
Computational
Description (TAIR10)
CENTER CITY (CCT); FUNCTIONS IN: RNA polymerase II transcription mediator activity; INVOLVED IN: photoperiodism, flowering, regulation of development, heterochronic, regulation of radial pattern formation; LOCATED IN: mediator complex, chloroplast; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Mediator complex, subunit Med12 (InterPro:IPR019035); Has 216 Blast hits to 184 proteins in 75 species: Archae - 0; Bacteria - 0; Metazoa - 42; Fungi - 65; Plants - 86; Viruses - 0; Other Eukaryotes - 23 (source: NCBI BLink).
Protein Annotations
eggNOG:ENOG410XPQKeggNOG:KOG4522EMBL:AY092618EMBL:AY092620EMBL:AY092621EMBL:AY092624EMBL:AY092627
EMBL:AY092628EMBL:AY092630EMBL:AY092632EMBL:AY092634EMBL:AY092635EMBL:AY092636EnsemblPlants:AT4G00450
EnsemblPlants:AT4G00450.1entrez:827954ExpressionAtlas:Q8RUK3ExpressionAtlas:Q8RUK8hmmpanther:PTHR13992hmmpanther:PTHR13992:SF25ncoils:Coil
PaxDb:Q8RUK3PaxDb:Q8RUK8PaxDb:Q8RWP7Pfam:PF09497STRING:3702.AT4G00450.1tair10-symbols:CCTtair10-symbols:CRP
TMHMM:TMhelixUniProt:Q8RUK3UniProt:Q8RUK8UniProt:Q8RWP7UniProt:Q8RWP8
Coordinates (TAIR10) chr4:+:202425..210666
Molecular Weight (calculated) 249401.00 Da
IEP (calculated) 8.99
GRAVY (calculated) -0.23
Length 2253 amino acids
Sequence (TAIR10)
(BLAST)
0001: MQRYHAANCT SAVNNSAIGG ASARDSGRAD SSSIGNYSLN SRRPPPLTPY KLKCEKDGLN SRLGPPDFHP PTSNSPEENL TKEYVQFGYK ETVDGLKESE
0101: EIILSQVHTF SKPVVHKCKE AVRKCLRAIN ESRALKRKAG QVYGVPLSGS LLCKPGFPEQ RSCGEETKKR WIESLSQQHK RLRSLADNIP GYRRKTLFEV
0201: LIRNNVPLLR ATWFIKVTYL NQVHCWAINW CDLVLLLFLQ EHLTRHKLLG VSNGQKMLLN ICNTSWMNFC HGIAHFLLSK LEIGHHRCFI QDQCKRIVQH
0301: QQAFTARKHL YILNGGIWCV FYSGTMLKGF FFLISLLIGF SSSYSFVNFH FALLQEKEIF EILQLLLPIV YGVLESIVLS QTYVQSLVAI AVRFIQEPAP
0401: GGSDLVDNSR RAYTLSALIE MVRYLVLAAP DTFVASDFFP LPPSVAACGP NDVSYTSKAY ENLEKLRSNS AEISAQFQGR GVLSRFEFLS FDYTISTIQR
0501: SADDLAKIAS AGYPQHNVAK AVQALDKALS DGDIRAAYSY LFEDLCNGAV DEAWITDVSP CLRSSLRWIG AISTSFVCSV FFLIEWATCD FRDFRAGVPK
0601: DIKFSGRKDC SQVYLVIQLL KQKILGGEFT ARKGKNCRNN FLGVSKPSGS MDAFESPGPL HDIIVCWIDQ HEVHKGGAKR LQLLVFELIR SGIFNPIAYV
0701: RQLIVSGMID VIQPAVDPER RMRHHRILKQ LPGCFVHETL EEAQLFGGDK LSEAVRTYSN ERRLLLRELL VEKGKYWNNL VLSDQKSKKI STSLSSVIFP
0801: RACNAKSNSK GPRKHTKSSV DIRELKERIS ALLQFPGMSC GVETPVRDEF QNSVKRSSGS VYSKMDQPEA TPGCEDCRRA KRPKMNDEKS SCYQGNSPIA
0901: SDEEDNWWIK KGSKTVESSL KVDPQIEITK QVPRGRQKMA RKTQSLAQLQ AARIEGSQGA STSHVCDNKV SCPHHGPGVE GENQKVVDVF RTSTPVDMVS
1001: VGNSLKQLQF VDKRSIAVWL TTAVRQLVEE PQKSSVRVGQ FNRGAPVEEK NTIRWKLGAD ELYSILFLLD ISLDLVSAVK FLLWLLPKAN STPSFAVQGG
1101: RNLVTVPRNV ENNMCEIGEA ILVSSLRRYE NILLSADLVP EAMTALMNRA ASLMSSNGKI SGSAALVYTR YILKRYGSLP SVVEWHNNFK ATSEKKLLSE
1201: LDHTRSGNGE YGNPLGVPAG VDNPDDYLRK KISIGGARPS RVGLSMRDVL QRHVEEATHY LKKLIGTGTM KASLAEKNDD GYQVAQQIVV GLMDCIRQTG
1301: GAAQEGDPSL VSSAVSAIIN SVGLSVARIT DFSLGNIYQN HPSGVDSSNI ARYILRIHIT CLCLLKEALG ERQSRVFEIA LATESSTALT GVFAPVKGSR
1401: GQHQLSPESY DSNANNSTID MSNGTGKMAL SRATKITAAV SALVIGSITH GVITLERIVG LLRLKDYLDF VQFVRRTKSS SNGSARSMGA SKVESPIEVY
1501: VHWFRLLVGN CKTVSEGLVL ELVGESSVVA ISRMQRMLPL KLVFPPAYSI IAFVLWRPFV SNSNSNSSVH EDTHRLYQSL TMAFHDVIKH LPFRDVCFRD
1601: TQGLYELIVA DSTDAEFASV FESHGLDMHL KSVAFAPLRA RLFLNSLIDC KVPSSGYSHE GVSEAKNRHQ GNGTKLVDKL VSVLDCLQPA KFHWQWVELR
1701: LLLNEQALAE KLENHDMPLT DAIRSSCPTS EKPDASENEK NFIQILLTRL LVRPDAVPLF SEVVHLFGRS VEDSMLKQAE WFLAGQDVLF GRKTIRQKLI
1801: IVGESKGLPT KPQFWKPWGW CNSSSSDHIT ANKAGKKRKF EITSIEEGEV IEEGSGSRKV LLPRVLDENS PSVGYGITTE RAFVQLVLPC IDQSSDESRS
1901: TFVNELVRQF SNIEQQLSSV TNRSTTSNKQ MGTASSGSEI SSNKGSTRKG LRGGSPSLAR RSSANTTDTS PPPSPAALRA SMSLRLQFLL RLLPVICGEP
2001: SFKNTRHALA STIVRLLGSR VVYEDYAVCS PRSELSKAET ESTIDPSSMA DLSSEVLFDR LLFVLHGLLS NHQPKWLKPR PSSNESSKDF TLFDRDAAES
2101: LQNELSRMQL PDTIRWRIQA AMPILLPSLR CSLSCQPHSV PPTALTLVQP SGSTAAAGTN QRNSPAISKS GTAAAQGKLK PTMLAPHQQQ EADNTDVVDP
2201: WTLLEDGTSS GLSSSNASNS SDMANLRATC WLKGAVRVRR TDLTYVGSVD DDS
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)