suba logo
AT3G60370.1
Subcellular Consensus
(Prediction and Experimental)
min: heatmap :max

.
SUBAcon:
plastid 1.000
ASURE: plastid
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
FP Images

Arabidopsis cell culture (plastidal marker)

At3g60370-GFP
(full-length)
plastidal marker-RFPoverlay

Images by Sandra Tanz
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no PPI data
Description (TAIR10) protein_coding : FKBP-like peptidyl-prolyl cis-trans isomerase family protein
Curator
Summary (TAIR10)
Encodes an immunophilin, FKBP20-2, that belongs to the FK-506 binding protein (FKBP) subfamily functioning as peptidyl-prolyl isomerases (PPIases) in protein folding. FKBP20-2 has a unique pair of cysteines at the C terminus and was found to be reduced by thioredoxin (Trx) (itself reduced by NADPH by means of NADP-Trx reductase). The FKBP20-2 protein, which contains only two of the five amino acids required for catalysis, showed a low level of PPIase activity that was unaffected on reduction by Trx. Genetic disruption of the FKBP20-2 gene provide evidence that FKBP20-2 participates specifically in the accumulation of the PSII supercomplex in the chloroplast thylakoid lumen by means of a mechanism that has yet to be determined.
Computational
Description (TAIR10)
FKBP-like peptidyl-prolyl cis-trans isomerase family protein; FUNCTIONS IN: FK506 binding, oxidoreductase activity, peptidyl-prolyl cis-trans isomerase activity; INVOLVED IN: photosystem II assembly; LOCATED IN: thylakoid, thylakoid lumen, chloroplast thylakoid lumen, chloroplast; EXPRESSED IN: 20 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Peptidyl-prolyl cis-trans isomerase, FKBP-type (InterPro:IPR001179); BEST Arabidopsis thaliana protein match is: FKBP-like peptidyl-prolyl cis-trans isomerase family protein (TAIR:AT4G19830.1); Has 7131 Blast hits to 6812 proteins in 1455 species: Archae - 6; Bacteria - 3821; Metazoa - 1227; Fungi - 400; Plants - 644; Viruses - 0; Other Eukaryotes - 1033 (source: NCBI BLink).
Protein Annotations
BioCyc:ARA:AT3G60370-MONOMERBioGrid:10522EC:5.2.1.8eggNOG:COG0545
eggNOG:ENOG410IV9CEMBL:AK228309EMBL:AL138646EMBL:BT029531
EMBL:CP002686EnsemblPlants:AT3G60370EnsemblPlants:AT3G60370.1entrez:825208
GeneID:825208Genevisible:Q0WRJ7GO:GO:0000413GO:GO:0003755
GO:GO:0006457GO:GO:0009507GO:GO:0009543GO:GO:0009579
GO:GO:0010207GO:GO:0016491GO:GO:0031977GO:GO:0055114
Gramene:AT3G60370.1hmmpanther:PTHR10516hmmpanther:PTHR10516:SF178HOGENOM:HOG000012423
InParanoid:Q0WRJ7IntAct:Q0WRJ7InterPro:IPR001179InterPro:IPR023566
KEGG:ath:AT3G60370OMA:QRENNAPPANTHER:PTHR10516PaxDb:Q0WRJ7
Pfam:PF00254Pfam:Q0WRJ7Pfscan:PS50059PhylomeDB:Q0WRJ7
PIR:T47848PRIDE:Q0WRJ7PRO:PR:Q0WRJ7PROSITE:PS50059
ProteinModelPortal:Q0WRJ7Proteomes:UP000006548RefSeq:NP_567098.2SMR:Q0WRJ7
STRING:3702.AT3G60370.1SUPFAM:SSF54534TAIR:AT3G60370UniGene:At.34461
UniProt:Q0WRJ7
Coordinates (TAIR10) chr3:-:22315000..22316533
Molecular Weight (calculated) 27193.60 Da
IEP (calculated) 8.65
GRAVY (calculated) -0.35
Length 242 amino acids
Sequence (TAIR10)
(BLAST)
001: MVTILSTPLS PRLTFLCETK LSLSRSNRSV CCSLSEEPKD QCLSRRSLVY VLVASPCLLL PALSSSAKTK SKSPYDERRL LEQNKRIQRE NNAPDEFPNF
101: VREGFEVKVL ASDNYIKADS GLIYRDFNVG QGDFPKDGQQ VTFHYIGYNE SGRRIDSTYI QGSPARIRMG TNALVPGFEM GIRDMKPGGR RRIIIPPELG
201: PPVGPSTFFS SKQFEVFDVE LLSIQNCERR TIIGFYSDVT CS
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)