AT3G57300.1
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Subcellular Consensus
(Prediction and Experimental) min:  :max.
SUBAcon:nucleus 1.000 ASURE: nucleus What is SUBAcon? |
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| Experimental Localisations and PPI |
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SUBAcon links
AGI-AGI relationships |
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| Description (TAIR10) | protein_coding : INO80 ortholog | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Curator Summary (TAIR10) |
Encodes the Arabidopsis INO80 ortholog of the SWI/SNF ATPase family. Functions as a positive regulator of DNA homologous recombination (HR). In INO80 mutants, the HR frequency is reduced to 15% of that in the wild-type. Mutation in INO80 does not affect sensitivity to genotoxic agents and efficiency of T-DNA integration. INO80 was also shown to regulate a subset of the Arabidopsis transcriptome. | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Computational Description (TAIR10) |
INO80 ortholog (INO80); FUNCTIONS IN: helicase activity, DNA binding, ATP binding, nucleic acid binding; INVOLVED IN: somatic cell DNA recombination, positive regulation of DNA repair, regulation of transcription; LOCATED IN: cellular_component unknown; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: DEAD-like helicase, N-terminal (InterPro:IPR014001), DNA binding domain, INO80 (InterPro:IPR020838), DNA/RNA helicase, C-terminal (InterPro:IPR001650), Helicase, superfamily 1/2, ATP-binding domain (InterPro:IPR014021), SNF2-related (InterPro:IPR000330); BEST Arabidopsis thaliana protein match is: SNF2 domain-containing protein / helicase domain-containing protein (TAIR:AT3G12810.1); Has 26461 Blast hits to 15529 proteins in 1767 species: Archae - 159; Bacteria - 7863; Metazoa - 5872; Fungi - 5586; Plants - 2348; Viruses - 196; Other Eukaryotes - 4437 (source: NCBI BLink). | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Protein Annotations |
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| Coordinates (TAIR10) | chr3:+:21199612..21207635 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Molecular Weight (calculated) | 172181.00 Da | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| IEP (calculated) | 9.30 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| GRAVY (calculated) | -0.64 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Length | 1507 amino acids | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Sequence (TAIR10) (BLAST) |
0001: MDPSRRPPKD SPYANLFDLE PLMKFRIPKP EDEVDYYGSS SQDESRSTQG GVVANYSNGS KSRMNASSKK RKRWTEAEDA EDDDDLYNQH VTEEHYRSML 0101: GEHVQKFKNR SKETQGNPPH LMGFPVLKSN VGSYRGRKPG NDYHGRFYDM DNSPNFAADV TPHRRGSYHD RDITPKIAYE PSYLDIGDGV IYKIPPSYDK 0201: LVASLNLPSF SDIHVEEFYL KGTLDLRSLA ELMASDKRSG VRSRNGMGEP RPQYESLQAR MKALSPSNST PNFSLKVSEA AMNSAIPEGS AGSTARTILS 0301: EGGVLQVHYV KILEKGDTYE IVKRSLPKKL KAKNDPAVIE KTERDKIRKA WINIVRRDIA KHHRIFTTFH RKLSIDAKRF ADGCQREVRM KVGRSYKIPR 0401: TAPIRTRKIS RDMLLFWKRY DKQMAEERKK QEKEAAEAFK REQEQRESKR QQQRLNFLIK QTELYSHFMQ NKTDSNPSEA LPIGDENPID EVLPETSAAE 0501: PSEVEDPEEA ELKEKVLRAA QDAVSKQKQI TDAFDTEYMK LRQTSEMEGP LNDISVSGSS NIDLHNPSTM PVTSTVQTPE LFKGTLKEYQ MKGLQWLVNC 0601: YEQGLNGILA DEMGLGKTIQ AMAFLAHLAE EKNIWGPFLV VAPASVLNNW ADEISRFCPD LKTLPYWGGL QERTILRKNI NPKRMYRRDA GFHILITSYQ 0701: LLVTDEKYFR RVKWQYMVLD EAQAIKSSSS IRWKTLLSFN CRNRLLLTGT PIQNNMAELW ALLHFIMPML FDNHDQFNEW FSKGIENHAE HGGTLNEHQL 0801: NRLHAILKPF MLRRVKKDVV SELTTKTEVT VHCKLSSRQQ AFYQAIKNKI SLAELFDSNR GQFTDKKVLN LMNIVIQLRK VCNHPELFER NEGSSYLYFG 0901: VTSNSLLPHP FGELEDVHYS GGQNPIIYKI PKLLHQEVLQ NSETFCSSVG RGISRESFLK HFNIYSPEYI LKSIFPSDSG VDQVVSGSGA FGFSRLMDLS 1001: PSEVGYLALC SVAERLLFSI LRWERQFLDE LVNSLMESKD GDLSDNNIER VKTKAVTRML LMPSKVETNF QKRRLSTGPT RPSFEALVIS HQDRFLSSIK 1101: LLHSAYTYIP KARAPPVSIH CSDRNSAYRV TEELHQPWLK RLLIGFARTS EANGPRKPNS FPHPLIQEID SELPVVQPAL QLTHRIFGSC PPMQSFDPAK 1201: LLTDSGKLQT LDILLKRLRA GNHRVLLFAQ MTKMLNILED YMNYRKYKYL RLDGSSTIMD RRDMVRDFQH RSDIFVFLLS TRAGGLGINL TAADTVIFYE 1301: SDWNPTLDLQ AMDRAHRLGQ TKDVTVYRLI CKETVEEKIL HRASQKNTVQ QLVMTGGHVQ GDDFLGAADV VSLLMDDAEA AQLEQKFREL PLQVKDRQKK 1401: KTKRIRIDAE GDATLEELED VDRQDNGQEP LEEPEKPKSS NKKRRAASNP KARAPQKAKE EANGEDTPQR TKRVKRQTKS INESLEPVFS ASVTESNKGF 1501: DPSSSAN |
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| See Also |
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Citation
If you find this resource useful please cite one of the following publications:
Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)
Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)