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AT3G52430.1
Subcellular Consensus
(Prediction and Experimental)

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SUBAcon:
plasma membrane 0.791
What is SUBAcon?
What is ASURE?
SUBAcon computations
Experimental Localisations and PPI
FP MS/MS PPI
SUBAcon links
AGI-AGI relationships
Coexpression PPI
Description (TAIR10) protein_coding : alpha/beta-Hydrolases superfamily protein
Curator
Summary (TAIR10)
Encodes a lipase-like gene that is important for salicylic acid signaling and function in resistance (R) gene-mediated and basal plant disease resistance. PAD4 can interact directly with EDS1, another disease resistance signaling protein. Expressed at elevated level in response to green peach aphid (GPA) feeding, and modulates the GPA feeding-induced leaf senescence through a mechanism that doesn't require camalexin synthesis and salicylic acid (SA) signaling. Required for the ssi2-dependent heightened resistance to GPA.
Computational
Description (TAIR10)
PHYTOALEXIN DEFICIENT 4 (PAD4); CONTAINS InterPro DOMAIN/s: Lipase, class 3 (InterPro:IPR002921); BEST Arabidopsis thaliana protein match is: senescence-associated gene 101 (TAIR:AT5G14930.2); Has 722 Blast hits to 622 proteins in 73 species: Archae - 0; Bacteria - 23; Metazoa - 17; Fungi - 11; Plants - 620; Viruses - 1; Other Eukaryotes - 50 (source: NCBI BLink).
Protein Annotations
BioGrid:9726EC:2.3.1.-eggNOG:ENOG410IJZDeggNOG:ENOG410Y7YAEMBL:AF188329EMBL:AL050300EMBL:CP002686
EMBL:EF470727EMBL:EF470728EMBL:EF470729EMBL:EF470731EMBL:EF470733EMBL:EF470735EMBL:EF470736
EMBL:EF470737EMBL:EF470741EMBL:EF470742EMBL:EF470743EMBL:EU405144EMBL:EU405145EMBL:EU405146
EMBL:EU405149EMBL:EU405150EMBL:EU405152EMBL:EU405153EMBL:EU405155EMBL:EU405159EMBL:EU405161
EMBL:EU405162EMBL:EU405163EMBL:EU405164EMBL:EU405173EMBL:EU405174EMBL:EU405175EMBL:EU405177
EMBL:EU405180EMBL:EU405181EMBL:EU405183EMBL:EU405188EMBL:EU405190EMBL:EU405192EMBL:EU405193
EMBL:EU405194EMBL:EU405195EMBL:EU405197EMBL:EU405205EMBL:EU405206EMBL:EU405208EMBL:EU405209
EMBL:EU405210EMBL:EU405212EMBL:EU405213EMBL:EU405214EMBL:EU405215EMBL:EU405217EMBL:EU405219
EMBL:EU405223EMBL:EU405224EMBL:EU405228EMBL:EU405231EMBL:EU405232EMBL:EU405237EnsemblPlants:AT3G52430
EnsemblPlants:AT3G52430.1entrez:824408ESTHER:arath-PAD4Gene3D:3.40.50.1820GeneID:824408Genevisible:Q9S745GO:GO:0001666
GO:GO:0002213GO:GO:0005634GO:GO:0005737GO:GO:0009617GO:GO:0009625GO:GO:0009626GO:GO:0009627
GO:GO:0009751GO:GO:0009816GO:GO:0009862GO:GO:0009873GO:GO:0010105GO:GO:0010150GO:GO:0010225
GO:GO:0010310GO:GO:0010618GO:GO:0010942GO:GO:0016042GO:GO:0016298GO:GO:0016740GO:GO:0031348
GO:GO:0051707GO:GO:0071327GO:GO:0080142GO:GO:0080151GO:GO:1900367GO:GO:1900426GO:GO:1901183
GO:GO:2000022GO:GO:2000031Gramene:AT3G52430.1hmmpanther:PTHR21493hmmpanther:PTHR21493:SF132InParanoid:Q9S745IntAct:Q9S745
InterPro:IPR002921InterPro:IPR029058KEGG:ath:AT3G52430OMA:RTKGHYMPaxDb:Q9S745Pfam:PF01764Pfam:Q9S745
PhylomeDB:Q9S745PIR:T08456PRIDE:Q9S745PRO:PR:Q9S745ProteinModelPortal:Q9S745Proteomes:UP000006548RefSeq:NP_190811.1
SMR:Q9S745STRING:3702.AT3G52430.1SUPFAM:SSF53474TAIR:AT3G52430tair10-symbols:ATPAD4tair10-symbols:PAD4UniGene:At.22858
UniGene:At.69183UniGene:At.69581UniProt:Q9S745
Coordinates (TAIR10) chr3:+:19431566..19434292
Molecular Weight (calculated) 60987.90 Da
IEP (calculated) 6.36
GRAVY (calculated) -0.19
Length 541 amino acids
Sequence (TAIR10)
(BLAST)
001: MDDCRFETSE LQASVMISTP LFTDSWSSCN TANCNGSIKI HDIAGITYVA IPAVSMIQLG NLVGLPVTGD VLFPGLSSDE PLPMVDAAIL KLFLQLKIKE
101: GLELELLGKK LVVITGHSTG GALAAFTALW LLSQSSPPSF RVFCITFGSP LLGNQSLSTS ISRSRLAHNF CHVVSIHDLV PRSSNEQFWP FGTYLFCSDK
201: GGVCLDNAGS VRLMFNILNT TATQNTEEHQ RYGHYVFTLS HMFLKSRSFL GGSIPDNSYQ AGVALAVEAL GFSNDDTSGV LVKECIETAT RIVRAPILRS
301: AELANELASV LPARLEIQWY KDRCDASEEQ LGYYDFFKRY SLKRDFKVNM SRIRLAKFWD TVIKMVETNE LPFDFHLGKK WIYASQFYQL LAEPLDIANF
401: YKNRDIKTGG HYLEGNRPKR YEVIDKWQKG VKVPEECVRS RYASTTQDTC FWAKLEQAKE WLDEARKESS DPQRRSLLRE KIVPFESYAN TLVTKKEVSL
501: DVKAKNSSYS VWEANLKEFK CKMGYENEIE MVVDESDAME T
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)