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AT3G51840.1
Subcellular Consensus
(Prediction and Experimental)

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SUBAcon:
peroxisome 1.000
ASURE: peroxisome
What is SUBAcon?
What is ASURE?
SUBAcon computations
Experimental Localisations and PPI
FP MS/MS PPI
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no PPI data
Description (TAIR10) protein_coding : acyl-CoA oxidase 4
Curator
Summary (TAIR10)
Encodes a short-chain acyl-CoA oxidase, which catalyzes the first step of peroxisomal fatty acid beta-oxidation during early, post-germinative growth in oilseed species. Null mutants virtually lack short-chain acyl-CoA and are resistant to 2,4-dichlorophenoxybutyric acid, which is converted to the herbicide and auxin analogue 2,4-dichlorophenoxyacetic acid by beta-oxidation. Despite the almost complete loss of short-chain activity, lipid catabolism and seedling growth and establishment was unaltered in the acx4 mutant. However, double mutants in acx3acx4 (acx3 encodes medium chain acyl CoA oxidase) were not viable and arrested during embryogenesis.
Computational
Description (TAIR10)
acyl-CoA oxidase 4 (ACX4); FUNCTIONS IN: oxidoreductase activity, acyl-CoA oxidase activity; INVOLVED IN: fatty acid beta-oxidation, short-chain fatty acid metabolic process, embryo development ending in seed dormancy; LOCATED IN: peroxisome; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Acyl-CoA oxidase/dehydrogenase, type1/2, C-terminal (InterPro:IPR013764), Acyl-CoA oxidase/dehydrogenase, type 1 (InterPro:IPR006090), Acyl-CoA dehydrogenase/oxidase (InterPro:IPR009100), Acyl-CoA dehydrogenase/oxidase, N-terminal (InterPro:IPR013786), Acyl-CoA oxidase/dehydrogenase, central domain (InterPro:IPR006091), Acyl-CoA dehydrogenase, conserved site (InterPro:IPR006089), Acyl-CoA dehydrogenase/oxidase C-terminal (InterPro:IPR009075), Acyl-CoA dehydrogenase, N-terminal (InterPro:IPR006092); BEST Arabidopsis thaliana protein match is: isovaleryl-CoA-dehydrogenase (TAIR:AT3G45300.1); Has 36828 Blast hits to 36765 proteins in 1995 species: Archae - 537; Bacteria - 24188; Metazoa - 1639; Fungi - 822; Plants - 341; Viruses - 0; Other Eukaryotes - 9301 (source: NCBI BLink).
Protein Annotations
BioCyc:ARA:AT3G51840-MONOMERBioCyc:MetaCyc:AT3G51840-MONOMERBioGrid:9665BRENDA:1.3.3.6EC:1.3.3.6eggNOG:COG1960eggNOG:KOG0138
EMBL:AB017643EMBL:AF049236EMBL:AY087793EMBL:AY094441EMBL:AY125536EMBL:CP002686EMBL:U72505
EnsemblPlants:AT3G51840EnsemblPlants:AT3G51840.1entrez:824347EvolutionaryTrace:Q96329Gene3D:1.10.540.10GeneID:824347Genevisible:Q96329
GO:GO:0000062GO:GO:0003995GO:GO:0003997GO:GO:0005777GO:GO:0006635GO:GO:0009055GO:GO:0009514
GO:GO:0009793GO:GO:0033539GO:GO:0046459GO:GO:0050660GO:GO:0052890GO:GO:0055088Gramene:AT3G51840.1
gramene_plant_reactome:1119445gramene_plant_reactome:6877654hmmpanther:PTHR10909hmmpanther:PTHR10909:SF331HOGENOM:HOG000131662InParanoid:Q96329InterPro:IPR006089
InterPro:IPR006091InterPro:IPR009075InterPro:IPR009100InterPro:IPR013786iPTMnet:Q96329KEGG:ath:AT3G51840KO:K00232
OMA:YQFAQDKPaxDb:Q96329PDB:2IX5PDB:2IX6PDBsum:2IX5PDBsum:2IX6Pfam:PF00441
Pfam:PF02770Pfam:PF02771Pfam:Q96329PhylomeDB:Q96329PIR:T46895PRIDE:Q96329PRO:PR:Q96329
PROSITE:PS00072PROSITE:PS00073ProteinModelPortal:Q96329Proteomes:UP000006548Reactome:R-ATH-71064RefSeq:NP_190752.1scanprosite:PS00072
scanprosite:PS00073SMR:Q96329STRING:3702.AT3G51840.1SUPFAM:SSF47203SUPFAM:SSF56645SwissLipids:SLP:000000862TAIR:AT3G51840
tair10-symbols:ACX4tair10-symbols:ATG6tair10-symbols:ATSCXUniGene:At.21620UniProt:Q96329
Coordinates (TAIR10) chr3:-:19225653..19229008
Molecular Weight (calculated) 47559.60 Da
IEP (calculated) 8.45
GRAVY (calculated) -0.07
Length 436 amino acids
Sequence (TAIR10)
(BLAST)
001: MAVLSSADRA SNEKKVKSSY FDLPPMEMSV AFPQATPAST FPPCTSDYYH FNDLLTPEEQ AIRKKVRECM EKEVAPIMTE YWEKAEFPFH ITPKLGAMGV
101: AGGSIKGYGC PGLSITANAI ATAEIARVDA SCSTFILVHS SLGMLTIALC GSEAQKEKYL PSLAQLNTVA CWALTEPDNG SDASGLGTTA TKVEGGWKIN
201: GQKRWIGNST FADLLIIFAR NTTTNQINGF IVKKDAPGLK ATKIPNKIGL RMVQNGDILL QNVFVPDEDR LPGVNSFQDT SKVLAVSRVM VAWQPIGISM
301: GIYDMCHRYL KERKQFGAPL AAFQLNQQKL VQMLGNVQAM FLMGWRLCKL YETGQMTPGQ ASLGKAWISS KARETASLGR ELLGGNGILA DFLVAKAFCD
401: LEPIYTYEGT YDINTLVTGR EVTGIASFKP ATRSRL
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)