AT3G44200.1
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Subcellular Consensus
(Prediction and Experimental) min:  :max.
SUBAcon:cytosol 1.000 What is SUBAcon? |
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| Experimental Localisations and PPI |
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SUBAcon links
AGI-AGI relationships |
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| Description (TAIR10) | protein_coding : NIMA (never in mitosis, gene A)-related 6 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Curator Summary (TAIR10) |
Encodes AtNek5, a member of the NIMA-related serine/threonine kinases (Neks) that have been linked to cell-cycle regulation in fungi and mammals. Plant Neks might be involved in plant development processes.Interacts physically with plant kinesins ARK1 and ARK2. Mutants show defects in root epidermal cell morphology, trichome branching and other epidermal cell abnormalities suggesting a rol e in epidermal cell differentiation. NEK6 co-localizes with cortical microtubules. | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Computational Description (TAIR10) |
NIMA (never in mitosis, gene A)-related 6 (NEK6); FUNCTIONS IN: protein serine/threonine kinase activity, protein kinase activity, kinase activity, ATP binding; INVOLVED IN: microtubule-based process, epidermal cell differentiation; LOCATED IN: cortical microtubule; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Protein kinase, ATP binding site (InterPro:IPR017441), Protein kinase, catalytic domain (InterPro:IPR000719), Serine/threonine-protein kinase domain (InterPro:IPR002290), Serine/threonine-protein kinase-like domain (InterPro:IPR017442), Protein kinase-like domain (InterPro:IPR011009), Serine/threonine-protein kinase, active site (InterPro:IPR008271); BEST Arabidopsis thaliana protein match is: NIMA-related serine/threonine kinase 1 (TAIR:AT1G54510.3); Has 127749 Blast hits to 124714 proteins in 4408 species: Archae - 106; Bacteria - 14910; Metazoa - 47444; Fungi - 12949; Plants - 30417; Viruses - 519; Other Eukaryotes - 21404 (source: NCBI BLink). | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Protein Annotations |
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| Coordinates (TAIR10) | chr3:+:15906788..15911365 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Molecular Weight (calculated) | 106395.00 Da | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| IEP (calculated) | 7.21 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| GRAVY (calculated) | -0.71 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Length | 956 amino acids | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Sequence (TAIR10) (BLAST) |
001: MESRMDQYEL MEQIGRGAFG AAILVHHKAE RKKYVLKKIR LARQTERCRR SAHQEMSLIA RVQHPYIVEF KEAWVEKGCY VCIVTGYCEG GDMAELMKKS 101: NGVYFPEEKL CKWFTQLLLA VEYLHSNYVL HRDLKCSNIF LTKDQDVRLG DFGLAKTLKA DDLTSSVVGT PNYMCPELLA DIPYGFKSDI WSLGCCIYEM 201: AAYRPAFKAF DMAGLISKVN RSSIGPLPPC YSPSLKALIK GMLRKNPEYR PNASEILKHP YLQPYVEQYR PTLSAASITP EKPLNSREGR RSMAESQNSN 301: SSSEKDNFYV SDKNIRYVVP SNGNKVTETD SGFVDDEDIL DHVQQSAENG NLQSVSATKP DGHGILKPVH SDQRPDVIQP RHPKTIRNIM MVLKEEKARE 401: NGSPMRSNRS RPSSVPTQKN NVETPSKIPK LGDIAHSSKT NASTPIPPSK LASDSARTPG SFPPKHHMPV IDSSPKLKPR NDRISPSPAA KHEAEEAMSV 501: KRRQRTPPTL PRRTSLIAHQ SRQLGADISN MAAKETAKLH PSVPSESETN SHQSRVHASP VSTTPEPKRT SVGSAKGMQS ESSNSISSSL SMQAFELCDD 601: ASTPYIDMTE HTTPDDHRRS CHSEYSYSFP DISSEMMIRR DEHSTSMRLT EIPDSVSGVQ NTIAHHQPER EQGSCPTVLK DDSPATLQSY EPNTSQHQHG 701: DDKFTVKEFV SSVPGPAPLP LHVEPSHQVN SHSDNKTSVM SQNSALEKNN SHSHPHPVVD DVIHVIRHSS FRVGSDQPVM ESVEVGVQNV DMGKLINVVR 801: DEMEVRKGAT PSESPTTRSI ISEPDSRTEP RPKEPDPITN YSETKSFNSC SDSSPAETRT NSFVPEEETT PTPPVKETLD IKSFRQRAEA LEGLLELSAD 901: LLEQSRLEEL AIVLQPFGKN KVSPRETAIW LAKSLKGMMI EDINNNNSSG SSRNCS |
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| See Also |
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Citation
If you find this resource useful please cite one of the following publications:
Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)
Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)