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AT3G25530.1
Subcellular Consensus
(Prediction and Experimental)
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SUBAcon:
cytosol 1.000
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
  • PMID:31871212 (2020): mitochondrion
  • PMID:31186290 (2019): cytosol None
  • PMID:30783145 (2019): extracellular region apoplast
  • PMID:30783145 (2019): extracellular region plant-type cell wall
  • PMID:29104584 (2017): nucleus nuclear matrix nucleolus
  • PMID:28865150 (2017): extracellular region plant-type cell wall
  • PMID:26781341 (2016): plasma membrane
  • PMID:26572690 (2016): extracellular region plant-type cell wall
  • PMID:25900983 (2015): Golgi Golgi apparatus Golgi membrane
  • PMID:24124904 (2013): plastid
  • PMID:23673981 (2013): plastid plastid stroma plastoglobules
  • PMID:22215637 (2012): plasma membrane
  • PMID:21166475 (2011): cytosol
  • PMID:19329564 (2009): peroxisome
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no PPI data
Description (TAIR10) protein_coding : glyoxylate reductase 1
Curator
Summary (TAIR10)
Encodes gamma-hydroxybutyrate dehydrogenase (AtGHBDH). Contains a NADP-binding domain. GHBDH is proposed to function in oxidative stress tolerance.
Computational
Description (TAIR10)
glyoxylate reductase 1 (GLYR1); FUNCTIONS IN: 3-hydroxybutyrate dehydrogenase activity, phosphogluconate dehydrogenase (decarboxylating) activity; INVOLVED IN: response to oxidative stress; LOCATED IN: cytosol; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: 6-phosphogluconate dehydrogenase, NAD-binding (InterPro:IPR006115), 6-phosphogluconate dehydrogenase, C-terminal-like (InterPro:IPR008927), Dehydrogenase, multihelical (InterPro:IPR013328), 3-hydroxyacid dehydrogenase/reductase (InterPro:IPR015815), 6-phosphogluconate dehydrogenase (InterPro:IPR006183), NAD(P)-binding domain (InterPro:IPR016040), 3-hydroxyisobutyrate dehydrogenase-related, conserved site (InterPro:IPR002204); BEST Arabidopsis thaliana protein match is: glyoxylate reductase 2 (TAIR:AT1G17650.1); Has 17561 Blast hits to 17531 proteins in 2324 species: Archae - 147; Bacteria - 10853; Metazoa - 400; Fungi - 503; Plants - 354; Viruses - 5; Other Eukaryotes - 5299 (source: NCBI BLink).
Protein Annotations
BioCyc:ARA:AT3G25530-MONOMERBioGrid:7470BRENDA:1.1.1.26BRENDA:1.1.1.61
BRENDA:1.1.1.79EC:1.1.1.79EC:1.1.1.n11eggNOG:COG2084
eggNOG:KOG0409EMBL:AB025639EMBL:AK316884EMBL:AY044183
EMBL:AY049298EMBL:BT025039EMBL:CP002686EnsemblPlants:AT3G25530
EnsemblPlants:AT3G25530.1entrez:822139EvolutionaryTrace:Q9LSV0Gene3D:1.10.1040.10
Gene3D:3.40.50.720GeneID:822139Genevisible:Q9LSV0GO:GO:0003858
GO:GO:0004616GO:GO:0005829GO:GO:0006979GO:GO:0030267
GO:GO:0051287hmmpanther:PTHR22981hmmpanther:PTHR22981:SF53HOGENOM:HOG000219608
InterPro:IPR002204InterPro:IPR006115InterPro:IPR008927InterPro:IPR013328
InterPro:IPR015815InterPro:IPR016040InterPro:IPR029154KEGG:ath:AT3G25530
KO:K18121OMA:MFKGKGPPaxDb:Q9LSV0PDB:3DOJ
PDBsum:3DOJPfam:PF03446Pfam:PF14833Pfam:Q9LSV0
PhylomeDB:Q9LSV0PIRSF:PIRSF000103PRIDE:Q9LSV0PRO:PR:Q9LSV0
ProMEX:Q9LSV0PROSITE:PS00895ProteinModelPortal:Q9LSV0Proteomes:UP000006548
RefSeq:NP_001030765.1RefSeq:NP_566768.1scanprosite:PS00895SMR:Q9LSV0
STRING:3702.AT3G25530.1SUPFAM:SSF48179SUPFAM:SSF51735TAIR:AT3G25530
tair10-symbols:ATGHBDHtair10-symbols:GHBDHtair10-symbols:GLYR1tair10-symbols:GR1
UniGene:At.21370UniProt:Q9LSV0
Coordinates (TAIR10) chr3:-:9271949..9273514
Molecular Weight (calculated) 30693.60 Da
IEP (calculated) 5.92
GRAVY (calculated) 0.08
Length 289 amino acids
Sequence (TAIR10)
(BLAST)
001: MEVGFLGLGI MGKAMSMNLL KNGFKVTVWN RTLSKCDELV EHGASVCESP AEVIKKCKYT IAMLSDPCAA LSVVFDKGGV LEQICEGKGY IDMSTVDAET
101: SLKINEAITG KGGRFVEGPV SGSKKPAEDG QLIILAAGDK ALFEESIPAF DVLGKRSFYL GQVGNGAKMK LIVNMIMGSM MNAFSEGLVL ADKSGLSSDT
201: LLDILDLGAM TNPMFKGKGP SMNKSSYPPA FPLKHQQKDM RLALALGDEN AVSMPVAAAA NEAFKKARSL GLGDLDFSAV IEAVKFSRE
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)