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AT3G25500.1
Subcellular Consensus
(Prediction and Experimental)

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SUBAcon:
plasma membrane 1.000
ASURE: plasma membrane
What is SUBAcon?
What is ASURE?
SUBAcon computations
Experimental Localisations and PPI
FP MS/MS PPI
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no PPI data
Description (TAIR10) protein_coding : formin homology 1
Curator
Summary (TAIR10)
Poly-L-proline-containing (PLP) protein that form part of the signal-transduction cascade that leads to rearrangement of the actin cytoskeleton. AFH1 is a nonprocessive formin that moves from the barbered end to the side of an actin filament after the nucleation event.
Computational
Description (TAIR10)
formin homology 1 (AFH1); FUNCTIONS IN: actin binding, protein binding, actin filament binding; INVOLVED IN: actin cytoskeleton organization; LOCATED IN: plasma membrane, membrane; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Actin-binding FH2/DRF autoregulatory (InterPro:IPR003104), Actin-binding FH2 (InterPro:IPR015425); BEST Arabidopsis thaliana protein match is: Actin-binding FH2 (formin homology 2) family protein (TAIR:AT2G43800.1); Has 17339 Blast hits to 10806 proteins in 665 species: Archae - 8; Bacteria - 1434; Metazoa - 6069; Fungi - 2556; Plants - 3390; Viruses - 718; Other Eukaryotes - 3164 (source: NCBI BLink).
Protein Annotations
BioGrid:7467eggNOG:ENOG410ISMYeggNOG:ENOG410XQWCEMBL:AB025639EMBL:AF174427EMBL:AK226743EMBL:AY080793
EMBL:AY142579EMBL:CP002686EnsemblPlants:AT3G25500EnsemblPlants:AT3G25500.1entrez:822136GeneID:822136Genevisible:Q9SE97
GO:GO:0003779GO:GO:0005618GO:GO:0005886GO:GO:0016020GO:GO:0016021GO:GO:0030036GO:GO:0045010
GO:GO:0051015GO:GO:0051016Gramene:AT3G25500.1hmmpanther:PTHR23213hmmpanther:PTHR23213:SF220HOGENOM:HOG000239832InParanoid:Q9SE97
InterPro:IPR015425iPTMnet:Q9SE97KEGG:ath:AT3G25500ncoils:CoilOMA:PEKASHKPaxDb:Q9SE97Pfam:PF02181
Pfam:Q9SE97Pfscan:PS51444PRIDE:Q9SE97PRO:PR:Q9SE97PROSITE:PS51444ProteinModelPortal:Q9SE97Proteomes:UP000006548
RefSeq:NP_189177.1SMART:SM00498SMR:Q9SE97STRING:3702.AT3G25500.1SUPFAM:SSF101447TAIR:AT3G25500tair10-symbols:AFH1
tair10-symbols:AHF1tair10-symbols:ATFH1tair10-symbols:FH1TMHMM:TMhelixUniGene:At.24691UniProt:Q9SE97
Coordinates (TAIR10) chr3:-:9251320..9254826
Molecular Weight (calculated) 115154.00 Da
IEP (calculated) 8.51
GRAVY (calculated) -0.49
Length 1051 amino acids
Sequence (TAIR10)
(BLAST)
0001: MLFFLFFFYL LLSSSSDLVF ADRRVLHEPF FPIDSPPPSP PSPPPLPKLP FSSTTPPSSS DPNASPFFPL YPSSPPPPSP ASFASFPANI SSLIVPHATK
0101: SPPNSKKLLI VAISAVSSAA LVALLIALLY WRRSKRNQDL NFSDDSKTYT TDSSRRVYPP PPATAPPTRR NAEARSKQRT TTSSTNNNSS EFLYLGTMVN
0201: QRGIDEQSLS NNGSSSRKLE SPDLQPLPPL MKRSFRLNPD VGSIGEEDEE DEFYSPRGSQ SGREPLNRVG LPGQNPRSVN NDTISCSSSS SGSPGRSTFI
0301: SISPSMSPKR SEPKPPVIST PEPAELTDYR FVRSPSLSLA SLSSGLKNSD EVGLNQIFRS PTVTSLTTSP ENNKKENSPL SSTSTSPERR PNDTPEAYLR
0401: SPSHSSASTS PYRCFQKSPE VLPAFMSNLR QGLQSQLLSS PSNSHGGQGF LKQLDALRSR SPSSSSSSVC SSPEKASHKS PVTSPKLSSR NSQSLSSSPD
0501: RDFSHSLDVS PRISNISPQI LQSRVPPPPP PPPPLPLWGR RSQVTTKADT ISRPPSLTPP SHPFVIPSEN LPVTSSPMET PETVCASEAA EETPKPKLKA
0601: LHWDKVRASS DREMVWDHLR SSSFKLDEEM IETLFVAKSL NNKPNQSQTT PRCVLPSPNQ ENRVLDPKKA QNIAILLRAL NVTIEEVCEA LLEGNADTLG
0701: TELLESLLKM APTKEEERKL KAYNDDSPVK LGHAEKFLKA MLDIPFAFKR VDAMLYVANF ESEVEYLKKS FETLEAACEE LRNSRMFLKL LEAVLKTGNR
0801: MNVGTNRGDA HAFKLDTLLK LVDVKGADGK TTLLHFVVQE IIRAEGTRLS GNNTQTDDIK CRKLGLQVVS SLCSELSNVK KAAAMDSEVL SSYVSKLSQG
0901: IAKINEAIQV QSTITEESNS QRFSESMKTF LKRAEEEIIR VQAQESVALS LVKEITEYFH GNSAKEEAHP FRIFLVVRDF LGVVDRVCKE VGMINERTMV
1001: SSAHKFPVPV NPMMPQPLPG LVGRRQSSSS SSSSSTSSSD EDEHNSISLV S
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)