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AT3G25230.1
Subcellular Consensus
(Prediction and Experimental)

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SUBAcon:
cytosol 1.000
What is SUBAcon?
What is ASURE?
SUBAcon computations
Experimental Localisations and PPI
FP MS/MS PPI
  • PMID:26572690 (2016): extracellular region plant-type cell wall
  • PMID:23903016 (2013): plant-type vacuole plant-type vacuole membrane
  • PMID:21433285 (2011): plasma membrane
  • PMID:21166475 (2011): cytosol
FP Images

7-day old Arabidopsis seedling (no marker)

RFP-At3g25230
(full-length)
overlay

SUBAcon links
AGI-AGI relationships
Coexpression PPI
Description (TAIR10) protein_coding : rotamase FKBP 1
Curator
Summary (TAIR10)
Encodes a a high molecular weight member of the FK506 binding protein (FKBP) family. It has three FKBP12-like domains, tetratricopeptide repeats, and a putative calmodulin binding domain. Modulates thermotolerance by interacting with HSP90.1 and affecting the accumulation of HsfA2-regulated sHSPs.
Computational
Description (TAIR10)
rotamase FKBP 1 (ROF1); FUNCTIONS IN: FK506 binding, peptidyl-prolyl cis-trans isomerase activity, calmodulin binding; INVOLVED IN: response to cadmium ion, response to heat, response to wounding; LOCATED IN: nucleus, cytoplasm; EXPRESSED IN: 26 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Tetratricopeptide TPR-1 (InterPro:IPR001440), Tetratricopeptide-like helical (InterPro:IPR011990), Tetratricopeptide repeat-containing (InterPro:IPR013026), Tetratricopeptide repeat (InterPro:IPR019734), Peptidyl-prolyl cis-trans isomerase, FKBP-type (InterPro:IPR001179); BEST Arabidopsis thaliana protein match is: FKBP-type peptidyl-prolyl cis-trans isomerase family protein (TAIR:AT5G48570.1); Has 23486 Blast hits to 15115 proteins in 1840 species: Archae - 212; Bacteria - 9362; Metazoa - 6200; Fungi - 1716; Plants - 1995; Viruses - 0; Other Eukaryotes - 4001 (source: NCBI BLink).
Protein Annotations
BioCyc:ARA:AT3G25230-MONOMERBioCyc:ARA:GQT-2059-MONOMERBioGrid:7448EC:5.2.1.8eggNOG:COG0545eggNOG:KOG0543EMBL:AB026647
EMBL:CP002686EMBL:U49453EMBL:U57838EnsemblPlants:AT3G25230EnsemblPlants:AT3G25230.1entrez:822117ExpressionAtlas:Q38931
Gene3D:1.25.40.10GeneID:822117Genevisible:Q38931GO:GO:0003755GO:GO:0005634GO:GO:0005737GO:GO:0006457
GO:GO:0070370hmmpanther:PTHR10516hmmpanther:PTHR10516:SF324HOGENOM:HOG000237912InParanoid:Q38931IntAct:Q38931InterPro:IPR001179
InterPro:IPR001440InterPro:IPR011990InterPro:IPR013026InterPro:IPR019734InterPro:IPR023566MINT:MINT-8375522ncoils:Coil
PANTHER:PTHR10516PaxDb:Q38931Pfam:PF00254Pfam:PF00515Pfam:PF13414Pfam:Q38931Pfscan:PS50005
Pfscan:PS50059Pfscan:PS50293PhylomeDB:Q38931PIR:S72485PRIDE:Q38931PRO:PR:Q38931PROSITE:PS50005
PROSITE:PS50059PROSITE:PS50293ProteinModelPortal:Q38931Proteomes:UP000006548Reactome:R-ATH-3371568RefSeq:NP_189160.3SMART:SM00028
SMR:Q38931STRING:3702.AT3G25230.2SUPFAM:SSF48452SUPFAM:SSF54534TAIR:AT3G25230tair10-symbols:ATFKBP62tair10-symbols:FKBP62
tair10-symbols:ROF1UniGene:At.25402UniProt:Q38931
Coordinates (TAIR10) chr3:+:9188257..9191137
Molecular Weight (calculated) 61456.10 Da
IEP (calculated) 4.95
GRAVY (calculated) -0.65
Length 551 amino acids
Sequence (TAIR10)
(BLAST)
001: MDANFEMPPV GGMNDDDDMD FGDGASFLKV GEEKEIQQGL KKKLLKEGEG YETPENGDEV EVHYTGTLLD GTKFDSSRDR ATPFKFTLGQ GQVIKGWDIG
101: IKTMKKGENA VFTIPAELAY GESGSPPTIP ANATLQFDVE LLKWDSVKDI CKDGGVFKKI LAVGEKWENP KDLDEVLVKF EAKLEDGTVV GKSDGVEFTV
201: KDGHFCPALT KAVKTMKKGE KVLLTVKPQY GFGEKGKPAS AGEGAVPPNA TLEINLELVS WKTVSEVTDD NKVVKKVLKE GDGYERPNEG AVVKVKLIGK
301: LQDGTVFLKK GHGENEEPFE FKTDEEQVVD GLDRAVMKMK KGEVALVTID PEYAFGSNES QQELAVVPPN STVTYEVDLL TFDKERESWD MNTEEKIEAA
401: SKKKEEGNSK FKGGKYSLAS KRYEKAVKFI EYDTSFSEEE KKQAKALKVA CNLNDAACKL KLKDYKQAEK LCTKVLELES TNVKALYRRA QAYMELSDLD
501: LAEFDVKKAL EIDPNNREVK LEQKRLKEKM KEFNKKEAKF YGNMFAKLSK E
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)