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AT3G25070.1
Subcellular Consensus
(Prediction and Experimental)
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SUBAcon:
plasma membrane 1.000
ASURE: plasma membrane
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
  • PMID:30447334 (2019): plasma membrane
  • PMID:26781341 (2016): plasma membrane
  • PMID:25641898 (2015): plasma membrane
  • PMID:24030099 (2013): plasma membrane
  • PMID:23110452 (2012): plasma membrane
  • PMID:22215637 (2012): plasma membrane
  • PMID:20374526 (2010): plasma membrane
  • PMID:19000159 (2009): plasma membrane
  • PMID:18686298 (2008): plant-type vacuole plant-type vacuole membrane
  • PMID:17317660 (2007): plasma membrane
  • PMID:15308754 (2004): plasma membrane
  • PMID:14506206 (2003): plasma membrane
SUBAcon links
AGI-AGI relationships
Coexpression PPI
Description (TAIR10) protein_coding : RPM1 interacting protein 4
Curator
Summary (TAIR10)
Encodes a member of the R protein complex and may represent a virulence target of type III pili effector proteins (virulence factors) from bacterial pathogens, which is 'guarded' by R protein complex (RPM1 and RPS2 proteins). RIN4 physically interacts with RPS2 and RPM1 in vivo. Bacterial avirulence (Avr) effectors AvrB, AvrRpm1, and AvrRpt2 induce a mobility shift in RIN4 and expression of AvrRpt2 induces rapid degradation of RIN4. RIN4 contains 2 sites for AvrRpt2 autocleavage, called RCS1 and RCS2. Overexpression of RIN4 inhibits multiple phenotypes associated with AvrRpt2 function and also inhibits PAMP-induced defense signaling. Attached to the plasma membrane at its carboxyl terminus. Cleaved by AvrRpt2 at two PxFGxW motifs, one releasing a large portion of RIN4 from the plasma membrane and both exposing amino-terminal residues that destabilized the carboxyl-terminal cleavage products by targeting them for N-end ubiquitylation and proteasomal degradation. Major virulence target of the TTSE HopF2Pto.
Computational
Description (TAIR10)
RPM1 interacting protein 4 (RIN4); FUNCTIONS IN: protein binding; INVOLVED IN: in 6 processes; LOCATED IN: plasma membrane, membrane; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: RPM1-interacting protein 4, defence response (InterPro:IPR008700); BEST Arabidopsis thaliana protein match is: defense protein-related (TAIR:AT5G48657.2); Has 373 Blast hits to 371 proteins in 56 species: Archae - 0; Bacteria - 8; Metazoa - 13; Fungi - 2; Plants - 331; Viruses - 0; Other Eukaryotes - 19 (source: NCBI BLink).
Protein Annotations
BioGrid:7429DIP:DIP-53466NeggNOG:ENOG410IWW8eggNOG:ENOG410YR29
EMBL:AB026647EMBL:AK117488EMBL:CP002686EMBL:EF470771
EMBL:EF470775EMBL:EF470784EnsemblPlants:AT3G25070EnsemblPlants:AT3G25070.1
entrez:822098EvolutionaryTrace:Q8GYN5ExpressionAtlas:Q8GYN5GeneID:822098
Genevisible:Q8GYN5GO:GO:0002237GO:GO:0005886GO:GO:0006468
GO:GO:0009626GO:GO:0009816GO:GO:0010204GO:GO:0012505
GO:GO:0016020GO:GO:0019897GO:GO:0034051Gramene:AT3G25070.1
hmmpanther:PTHR33159hmmpanther:PTHR33159:SF6HOGENOM:HOG000030266InParanoid:Q8GYN5
IntAct:Q8GYN5InterPro:IPR008700iPTMnet:Q8GYN5KEGG:ath:AT3G25070
KO:K13456OMA:WENDDNTPaxDb:Q8GYN5PDB:2NUD
PDBsum:2NUDPfam:PF05627Pfam:Q8GYN5PhylomeDB:Q8GYN5
PMAP-CutDB:Q8GYN5PRIDE:Q8GYN5PRO:PR:Q8GYN5ProteinModelPortal:Q8GYN5
Proteomes:UP000006548RefSeq:NP_189143.2STRING:3702.AT3G25070.1SwissPalm:Q8GYN5
TAIR:AT3G25070tair10-symbols:RIN4UniGene:At.43082UniProt:Q2HII6
UniProt:Q8GYN5
Coordinates (TAIR10) chr3:+:9132458..9133747
Molecular Weight (calculated) 23372.40 Da
IEP (calculated) 9.59
GRAVY (calculated) -1.41
Length 211 amino acids
Sequence (TAIR10)
(BLAST)
001: MARSNVPKFG NWEAEENVPY TAYFDKARKT RAPGSKIMNP NDPEYNSDSQ SQAPPHPPSS RTKPEQVDTV RRSREHMRSR EESELKQFGD AGGSSNEAAN
101: KRQGRASQNN SYDNKSPLHK NSYDGTGKSR PKPTNLRADE SPEKVTVVPK FGDWDENNPS SADGYTHIFN KVREERSSGA NVSGSSRTPT HQSSRNPNNT
201: SSCCCFGFGG K
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)