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AT3G20780.1
Subcellular Consensus
(Prediction and Experimental)
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SUBAcon:
nucleus 1.000
ASURE: nucleus
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
  • PMID:30961429 (2019): nucleus
  • PMID:28865150 (2017): extracellular region plant-type cell wall
  • PMID:24134884 (2013): cytoskeleton microtubules
SUBAcon links
AGI-AGI relationships
Coexpression PPI
Description (TAIR10) protein_coding : topoisomerase 6 subunit B
Curator
Summary (TAIR10)
Encodes putative eukaryotic homolog of archaebacterial topoisomerase VI subunit B, TOP6B. Is essential for endoreduplication and is involved in cell expansion and cell proliferation.
Computational
Description (TAIR10)
topoisomerase 6 subunit B (TOP6B); CONTAINS InterPro DOMAIN/s: DNA topoisomerase VI, subunit B, transducer (InterPro:IPR015320), Ribosomal protein S5 domain 2-type fold (InterPro:IPR020568), Ribosomal protein S5 domain 2-type fold, subgroup (InterPro:IPR014721), ATPase-like, ATP-binding domain (InterPro:IPR003594); Has 873 Blast hits to 542 proteins in 165 species: Archae - 495; Bacteria - 44; Metazoa - 2; Fungi - 2; Plants - 34; Viruses - 0; Other Eukaryotes - 296 (source: NCBI BLink).
Protein Annotations
BioCyc:ARA:AT3G20780-MONOMEREC:5.99.1.3eggNOG:COG1389eggNOG:ENOG410IFIB
EMBL:AB025629EMBL:AJ297843EMBL:CP002686EnsemblPlants:AT3G20780
EnsemblPlants:AT3G20780.1entrez:821626Gene3D:3.30.230.10Gene3D:3.30.565.10
GeneID:821626Genevisible:Q9C5V6GO:GO:0000902GO:GO:0003677
GO:GO:0003735GO:GO:0003918GO:GO:0005524GO:GO:0005634
GO:GO:0006265GO:GO:0007389GO:GO:0009330GO:GO:0009741
GO:GO:0010026GO:GO:0042023GO:GO:0042802Gramene:AT3G20780.1
HAMAP:MF_00322hmmpanther:PTHR10871hmmpanther:PTHR10871:SF4HOGENOM:HOG000264909
InParanoid:Q9C5V6IntAct:Q9C5V6InterPro:IPR003594InterPro:IPR005734
InterPro:IPR014721InterPro:IPR015320InterPro:IPR020568iPTMnet:Q9C5V6
KEGG:ath:AT3G20780OMA:AIVNPHAPANTHER:PTHR10871:SF4PaxDb:Q9C5V6
Pfam:PF02518Pfam:PF09239Pfam:Q9C5V6PhylomeDB:Q9C5V6
PRIDE:Q9C5V6PRO:PR:Q9C5V6ProDom:PD013790ProteinModelPortal:Q9C5V6
Proteomes:UP000006548RefSeq:NP_188714.2SMR:Q9C5V6STRING:3702.AT3G20780.1
SUPFAM:SSF54211SUPFAM:SSF55874TAIR:AT3G20780tair10-symbols:ATTOP6B
tair10-symbols:BIN3tair10-symbols:HYP6tair10-symbols:RHL3tair10-symbols:TOP6B
UniGene:At.8106UniProt:Q9C5V6
Coordinates (TAIR10) chr3:-:7264025..7268498
Molecular Weight (calculated) 75856.40 Da
IEP (calculated) 9.69
GRAVY (calculated) -0.49
Length 670 amino acids
Sequence (TAIR10)
(BLAST)
001: MAGDDLVETK KGSSKNSKDS NESKLKQKSP AEFFAENKNI AGFDNPGKSL YTTVRELVEN ALDSAESISE LPEVEVTIEE IVKSKFNSMI GLIDRERVDT
101: QLYDDYETEK ARGKRLAKEA RASEIQAKNL ASGKKNKEPG VSKVLKARGE ASYYKVTCKD NGKGMPHDDI PNMFGRVLSG TKYGLKQTRG KFGLGAKMAL
201: IWSKMSTGLP IEISSSMKSQ NYVTFCRLDI DIHRNIPHIH LHEKKGNKEK WHGAEIQVVI EGNWTTYRSK ILHYMRQMAV ITPYAQFLFR FISETPEKNV
301: TIKFTRRTDV MPPIPIETKH HPSSVDLLLI KRLITDTSKK TLLQFLQNEF VNINKTLAAR LIGEMGPDFG PSMAVKSVTS QQMVRIHQLF RQAKFDDPSG
401: DCLSPAGEYN LRLGIIKELH PDMVATYSGS AQVFEGHPFI VEAGVSLGGR DVKQGINIFR FANRIPLLFE QGADVVTRTA LKRINWNSYK INQTQDKIGV
501: FVSIVSTKIP FKGTGKEYIG DDISEIATAV KSAIQQCCIQ LKSKIVKRLQ AREQQERKRS LSRYIPDATG AVYEVLKQMT EEHKTKRKRY GEEDIVMLDK
601: VSKQIITKET LKEKLAEHVE QVDYEMALEY ATQSGVSEEP RENIYLQHLD PNKSNFIDLH SPTFVFRLML
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)