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AT3G19760.1
Subcellular Consensus
(Prediction and Experimental)

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SUBAcon:
nucleus 1.000
ASURE: nucleus
What is SUBAcon?
What is ASURE?
SUBAcon computations
Experimental Localisations and PPI
FP MS/MS PPI
  • PMID:27177187 (2016): nucleus
  • PMID:25900983 (2015): Golgi
  • PMID:25900983 (2015): plant-type vacuole plant-type vacuole membrane
  • PMID:25900983 (2015): Golgi trans-Golgi network multivesicular body
  • PMID:25900983 (2015): Golgi trans-Golgi network early endosome
  • PMID:25900983 (2015): Golgi trans-Golgi network
  • PMID:25900983 (2015): Golgi Golgi apparatus Golgi membrane
  • PMID:23396599 (2013): nucleus nuclear envelope nuclear inner membrane
  • PMID:15496452 (2005): nucleus
  • PMID:14617066 (2003): nucleus
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no PPI data
Description (TAIR10) protein_coding : eukaryotic initiation factor 4A-III
Curator
Summary (TAIR10)
Encodes an RNA helicase that may be a component of the Exon Junction Complex. Subcellular localization is modulated by stress. Under normal conditions it is localized to the nuceloplasm but under hyopoxic conditions it localizes to the nucleolus and splicing speckles.
Computational
Description (TAIR10)
eukaryotic initiation factor 4A-III (EIF4A-III); FUNCTIONS IN: protein binding, ATP-dependent helicase activity; INVOLVED IN: mRNA processing, response to hypoxia; LOCATED IN: in 6 components; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 16 growth stages; CONTAINS InterPro DOMAIN/s: RNA helicase, DEAD-box type, Q motif (InterPro:IPR014014), DNA/RNA helicase, DEAD/DEAH box type, N-terminal (InterPro:IPR011545), DEAD-like helicase, N-terminal (InterPro:IPR014001), DNA/RNA helicase, C-terminal (InterPro:IPR001650), Helicase, superfamily 1/2, ATP-binding domain (InterPro:IPR014021); BEST Arabidopsis thaliana protein match is: DEA(D/H)-box RNA helicase family protein (TAIR:AT1G51380.1); Has 50040 Blast hits to 49280 proteins in 3163 species: Archae - 836; Bacteria - 27183; Metazoa - 6400; Fungi - 4843; Plants - 2693; Viruses - 42; Other Eukaryotes - 8043 (source: NCBI BLink).
Protein Annotations
BioCyc:ARA:GQT-2386-MONOMERBioGrid:6845EC:3.6.4.13eggNOG:COG0513eggNOG:KOG0328EMBL:AJ010456EMBL:AP000417
EMBL:AY050367EMBL:BT002207EMBL:CP002686EnsemblPlants:AT3G19760EnsemblPlants:AT3G19760.1entrez:821513Gene3D:3.40.50.300
GeneID:821513Genevisible:Q94A52GO:GO:0001666GO:GO:0003723GO:GO:0004004GO:GO:0005524GO:GO:0005634
GO:GO:0005654GO:GO:0005730GO:GO:0006364GO:GO:0008380GO:GO:0010468GO:GO:0010501GO:GO:0016020
GO:GO:0016607GO:GO:0035145GO:GO:0071013Gramene:AT3G19760.1HOGENOM:HOG000268797InParanoid:Q94A52IntAct:Q94A52
InterPro:IPR001650InterPro:IPR011545InterPro:IPR014001InterPro:IPR014014InterPro:IPR027417iPTMnet:Q94A52KEGG:ath:AT3G19760
KO:K13025OMA:TATFCISPaxDb:Q94A52Pfam:PF00270Pfam:PF00271Pfam:Q94A52Pfscan:PS51192
Pfscan:PS51194Pfscan:PS51195PhylomeDB:Q94A52PIR:T51737PRIDE:Q94A52PRO:PR:Q94A52PROSITE:PS51192
PROSITE:PS51194PROSITE:PS51195ProteinModelPortal:Q94A52Proteomes:UP000006548Reactome:R-ATH-975957RefSeq:NP_188610.1SMART:SM00487
SMART:SM00490SMR:Q94A52STRING:3702.AT3G19760.1SUPFAM:SSF52540TAIR:AT3G19760tair10-symbols:EIF4A-IIIUniGene:At.22577
UniProt:Q94A52
Coordinates (TAIR10) chr3:+:6863790..6866242
Molecular Weight (calculated) 45847.30 Da
IEP (calculated) 6.13
GRAVY (calculated) -0.27
Length 408 amino acids
Sequence (TAIR10)
(BLAST)
001: MATANPGRGG GRRGGGAMDD DKLVFETTDG IEPITSFNDM GIKEDVLRGV YEYGFEKPSA IQQRAVMPIL QGRDVIAQAQ SGTGKTSMIA LSVCQVVDTS
101: SREVQALILS PTRELATQTE KTIQAIGLHA NIQAHACIGG NSVGEDIRKL EHGVHVVSGT PGRVCDMIKR RSLRTRAIKL LILDESDEML SRGFKDQIYD
201: VYRYLPPDLQ VCLVSATLPH EILEMTSKFM TEPVKILVKR DELTLEGIKQ FFVAVEKEEW KFDTLCDLYD TLTITQAVIF CNTKRKVDYL SEKMRSHNFT
301: VSSMHGDMPQ KERDAIMNEF RSGDSRVLIT TDVWARGIDV QQVSLVINYD LPNNRELYIH RIGRSGRFGR KGVAINFVKS DDIKILRDIE QYYSTQIDEM
401: PMNVADLI
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)