AT3G19050.1
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Subcellular Consensus
(Prediction and Experimental) min:  :max.
SUBAcon:nucleus 0.832 What is SUBAcon? |
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| Experimental Localisations and PPI |
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SUBAcon links
AGI-AGI relationships |
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| Description (TAIR10) | protein_coding : phragmoplast orienting kinesin 2 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Curator Summary (TAIR10) |
PHRAGMOPLAST ORIENTING KINESIN 2 is one of the two Arabidopsis homologs isolated in yeast two-hybrid screen for interaction partners of maize gene TANGLED1 (TAN1). Based on sequence homology in their motor domains, POK1 and POK2 belong to the kinesin-12 class which also includes the well-characterized group of phragmoplast-associated kinesins AtPAKRPs. Both kinesins are composed of an N-terminal motor domain throughout the entire C terminus and putative cargo binding tail domains. The expression domains for POK2 constructs were broader than those for POK1; both are expressed in tissues enriched for dividing cells. The phenotype of pok1/pok2 double mutants strongly resembles that of maize tan1 mutants, characterized by misoriented mitotic cytoskeletal arrays and misplaced cell walls. | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Computational Description (TAIR10) |
phragmoplast orienting kinesin 2 (POK2); FUNCTIONS IN: microtubule motor activity, ATP binding; INVOLVED IN: cytokinesis; EXPRESSED IN: root vascular system, primary root tip, lateral root primordium; CONTAINS InterPro DOMAIN/s: Kinesin, motor region, conserved site (InterPro:IPR019821), Kinesin, motor domain (InterPro:IPR001752); BEST Arabidopsis thaliana protein match is: phragmoplast orienting kinesin 1 (TAIR:AT3G17360.1); Has 204267 Blast hits to 80386 proteins in 3219 species: Archae - 3327; Bacteria - 35963; Metazoa - 90351; Fungi - 17822; Plants - 12667; Viruses - 746; Other Eukaryotes - 43391 (source: NCBI BLink). | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Protein Annotations |
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| Coordinates (TAIR10) | chr3:+:6578047..6590106 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Molecular Weight (calculated) | 315080.00 Da | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| IEP (calculated) | 4.86 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| GRAVY (calculated) | -0.59 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Length | 2771 amino acids | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Sequence (TAIR10) (BLAST) |
0001: MSKETKLSRR DSDNHDDEIE NVPENLRASL LSLTSNDSLK NPKHECGSKI DRTPSKPRAK NPDPALPLRT PDKYRSAAAF SKNRFGWGDK CDSITNTTNA 0101: ALLNTTPKTG RVVGRAYSET NSTQNTPTKS VSKPPGSCYR GKLDGTGTVR AGGYASLYKG LSSSSGQVST VVNSVEVPHF SLKEDPSFWM DHNVQILIRV 0201: RPLNSMERSI NGYNRCLKQE SSQCVAWIGP PETRFQFDHV ACETIDQETL FRVAGLPMVE NCLSGYNSCI FAYGQTGSGK TYTMLGEVGD LEFKPSPNRG 0301: MMPRIFEFLF ARIQAEEESR RDERLKYNCK CSFLEIYNEQ ITDLLEPSST NLQLREDIKS GVYVENLTEC EVQSVQDILG LITQGSLNRR VGATNMNRES 0401: SRSHSVFTCV IESRWEKDST ANMRFARLNL VDLAGSERQK TSGAEGDRLK EAASINKSLS TLGHVIMVLV DVANGKPRHI PYRDSRLTFL LQDSLGGNSK 0501: TMIIANASPS VSCAAETLNT LKFAQRAKLI QNNAVVNEDS NEDVLELRRQ IRLLKEELSL LKRQNISRAL SFGSATANFA ESQVDSPSSV MHETGQQQAG 0601: NLLVYESGGC VRMSRKQLKS LEITLAGSLR REHVADASIK KLEAEIEHLN RLVRQREEDT RSTKMMLRFR EDKIQRLESL LGNHISADSF LLEENNVLSE 0701: EIQLLQAKID KNPELTRFAL ENIRLLDQLR RFQEFYEEGE REILLGEVSN LRNQLFQFLD ENSDWQKHVD DGIEPQGASR MSKENCSLQE ELKKTCYELE 0801: KCRSNLGSCL EENAKLSREI NDLQAMVSDI RACTPDEHSS VNKQKALLGT QNFEPHETLA CEQANYVEEI IKLQLDLDVQ KIILDEERTL RGDTEAQAVR 0901: LKFDIEVLKD QLLLISKQQK NVYSELGETK SAVAALESQN IILIQEAVEL RRIKENYFEL LKKQELDIPA MKSKQCDEFK DNPAEDSEID TKFKKMQASL 1001: EKAKRLNMLY KSDIASKACG DEEMDEVCKQ AEAATAEVIV CLQNELEVLQ KEVNDFQSKE NVTEKQVEIL ETQMEELQDK LRDTTMDNEQ LQEQLRGKDM 1101: ELLIISNEME LLTSELEEIL LNGNEGLTDA CYQADLISGS LPDKRIWISE QVGGLIRTLS ERELMIEDLE SCLEDANKKR CDIESMLKSL KGAAIVMNEA 1201: HQREFEEKET DVLLLKSQLC TKTETILRLQ EKLKMAERLI YEASDCATAS LIIVNRYSEV TESHTFELKQ KDFQVAESTG TILSLKQQVQ DLEATCKEFR 1301: SKLLEEEKNA SAMEQKLEEI EETSISAMKE KLSELKGGVS DLRSCITMCQ EHDKYTEAEN SLSSPAHCSE GQEPGRNVVV SSCIEKTPNN NHTESMRLSS 1401: KVSSERGKVI ILLKQEMESA LASLKEVQVE MANLKGEKEE LKASEKRSLS NLNDLAAQIC NLNTVMSNME EQYEHKMEVT DHKLKTLEHE IAKMKIEADQ 1501: EYVENLCILK KFEEAQGTIR EADITVNELV IANEKMRFDL EKQKKRGISL VGEKKALVEK LQELESINVK ENEKLAYLEK LFESSLMGIG NLVEELATVV 1601: RKLQDESSVA LTGMAKDLSE LKSWVSETNS ARLFLEDIWS EIIMKDCAIS VLHLCHMGIL LETVTGINTE NGLLQRGLCV SNSSIAGLRD NNLRLRRELE 1701: MFANLKGKLL TDIKNGFERI SRNEEATNLL TTKLSSFDQK ISGLQYQEDL MLQRSNSMGS QLDILLKEID LSNGDLAETL LEQERHLNQK NDFFDTEVQL 1801: YLMDLCSKDV ELLVLAQTAK EYSSCLAVVD RELLDHHVIV EDLKEKLIVS QVEGELKDQC LVDNKLETVS VKEELTEAQS KIKVLSSDLD RSVQKIAEID 1901: EVNKDFGERV IFLESSITGL QQELAMKASE LYSLEHSRSV TAEELDIKER DVQVYADIVS SLKKENVSLK NKFIHFGEDQ FKALDVTRLS IAKCSHLTED 2001: SKKLEKLTRD GMAISDKMLQ LICENVDKAS VFADTVQSLQ IDVQELLSEN LNLHDELLRK DDVLKGLSFD LSLLQESASN SRDKKDETKE IMVHVEALEK 2101: TLALKTFELE DAVSHAQMLE VRLQESKEIT RNLEVDTEKA RKCQEKLSAE NKDIRAEAED LLAEKCSLEE EMIQTKKVSE SMEMELFNLR NALGQLNDTV 2201: AFTQRKLNDA IDERDNLQDE VLNLKEEFGK MKSEAKEMEA RYIEAQQIAE SRKTYADERE EEVKLLEGSV EELEYTINVL ENKVNVVKDE AERQRLQREE 2301: LEMELHTIRQ QMESARNADE EMKRILDEKH MDLAQAKKHI EALERNTADQ KTEITQLSEH ISELNLHAEA QASEYMHKFK ELEAMAEQVK PEIHVSQAID 2401: SSLSKGSGKP RGSGSPFRCI GLGITQQMRS EKDEELAAAR LRIEELETVV STRQKEIFLL NSKLAKVDSM THDINRVLLG VKQNVTNCAS FLDSQQVLKI 2501: AEMLQHNSSD SRERDLEVSH LKQQLNEYNE KRQGWIEEIE GKQTELVTAQ IKLEEHRQYQ QLLKKENELL KKENFSHKIK VMELEGEVKK LSSHQNPEWR 2601: TRDQARIKEE NNVLKLQLDE LNLKLRRADV SVSRAKEELA FYRASSVKNP HSNFDKTHQL STKLKETEED RMQLAQELLS LCTSILKAAG VTGEDFTDIN 2701: PEVAEEALEQ LKTKLGLLES EVHHFRLKGK AKSRRSRNPE RKMPSMPSPR RSWSQSPRSM SQVPFFSSLD R |
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| See Also |
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Citation
If you find this resource useful please cite one of the following publications:
Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)
Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)