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AT3G17360.1
Subcellular Consensus
(Prediction and Experimental)
min: heatmap :max

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SUBAcon:
nucleus 0.988
ASURE: cytoskeleton
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
  • PMID:24972597 (2014): cytosol cell plate
  • PMID:24972597 (2014): cytoskeleton microtubules
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no PPI data
Description (TAIR10) protein_coding : phragmoplast orienting kinesin 1
Curator
Summary (TAIR10)
PHRAGMOPLAST ORIENTING KINESIN 1 is one of the two Arabidopsis homologs isolated in yeast two-hybrid screen for interaction partners of maize gene TANGLED1 (TAN1). Based on sequence homology in their motor domains, POK1 and POK2 belong to the kinesin-12 class which also includes the well-characterized group of phragmoplast-associated kinesins AtPAKRPs. Both kinesins are composed of an N-terminal motor domain throughout the entire C terminus and putative cargo binding tail domains. The expression domains for POK1 constructs were more limited than those for POK2; both are expressed in tissues enriched for dividing cells. The phenotype of pok1/pok2 double mutants strongly resembles that of maize tan1 mutants, characterized by misoriented mitotic cytoskeletal arrays and misplaced cell walls.
Computational
Description (TAIR10)
phragmoplast orienting kinesin 1 (POK1); FUNCTIONS IN: microtubule motor activity, ATP binding; INVOLVED IN: cytokinesis; EXPRESSED IN: 17 plant structures; EXPRESSED DURING: 6 growth stages; CONTAINS InterPro DOMAIN/s: Kinesin, motor region, conserved site (InterPro:IPR019821), Kinesin, motor domain (InterPro:IPR001752); BEST Arabidopsis thaliana protein match is: phragmoplast orienting kinesin 2 (TAIR:AT3G19050.1); Has 97051 Blast hits to 52483 proteins in 2606 species: Archae - 1597; Bacteria - 13842; Metazoa - 45578; Fungi - 8395; Plants - 6409; Viruses - 244; Other Eukaryotes - 20986 (source: NCBI BLink).
Protein Annotations
BioCyc:ARA:GQT-1801-MONOMERDIP:DIP-46422NeggNOG:COG5059eggNOG:KOG4280
EMBL:AB022216EMBL:CP002686EMBL:DQ399529EnsemblPlants:AT3G17360
EnsemblPlants:AT3G17360.1entrez:820999Gene3D:3.40.850.10GeneID:820999
Genevisible:Q27IK7GO:GO:0000281GO:GO:0000911GO:GO:0003777
GO:GO:0005524GO:GO:0005871GO:GO:0005874GO:GO:0007018
GO:GO:0009524GO:GO:0016887Gramene:AT3G17360.1hmmpanther:PTHR24115
hmmpanther:PTHR24115:SF417HOGENOM:HOG000084308InParanoid:Q27IK7IntAct:Q27IK7
InterPro:IPR001752InterPro:IPR019821InterPro:IPR024658InterPro:IPR027417
InterPro:IPR027640iPTMnet:Q27IK7KEGG:ath:AT3G17360KO:K10400
ncoils:CoilOMA:AFWKDRNPANTHER:PTHR24115PaxDb:Q27IK7
Pfam:PF00225Pfam:PF12711Pfam:Q27IK7Pfscan:PS50067
PhylomeDB:Q27IK7PRIDE:Q27IK7PRINTS:PR00380PRO:PR:Q27IK7
PROSITE:PS00411PROSITE:PS50067ProteinModelPortal:Q27IK7Proteomes:UP000006548
RefSeq:NP_188362.2scanprosite:PS00411SMART:SM00129STRING:3702.AT3G17360.1
SUPFAM:SSF52540TAIR:AT3G17360tair10-symbols:POK1UniGene:At.38736
UniProt:Q27IK7
Coordinates (TAIR10) chr3:+:5936108..5946205
Molecular Weight (calculated) 233892.00 Da
IEP (calculated) 5.03
GRAVY (calculated) -0.61
Length 2066 amino acids
Sequence (TAIR10)
(BLAST)
0001: MSRNVPRIEM PESEENEFAS LSLFSPSRPP LNSIPDPSQI QKANHLPHFD LVQKLEGTRA QHQRTLGPEK KFEVLEGRAG NSSDSNPKIV NRNGKSRSEP
0101: NSAQSTPTRN GARVSLGGGC ATGARFLQSF GGRGRIPRGV SIAESVSFAE TTPHFELNED HSFWKDHNVQ VLIRLRPLGT MERANQGYGK CLKQESPQTL
0201: VWLGHPEARF TFDHVASETI SQEKLFRVAG LPMVENCLSG YNSCVFAYGQ TGSGKTYTMM GEISEAEGSL GEDCGVTARI FEYLFSRIKM EEEERRDENL
0301: KFSCKCSFLE IYNEQITDLL EPSSTNLQLR EDLGKGVYVE NLVEHNVRTV SDVLKLLLQG ATNRKIAATR MNSESSRSHS VFTCTIESLW EKDSLTRSRF
0401: ARLNLVDLAG SERQKSSGAE GDRLKEAANI NKSLSTLGLV IMSLVDLAHG KHRHVPYRDS RLTFLLQDSL GGNSKTMIIA NVSPSLCSTN ETLSTLKFAQ
0501: RAKLIQNNAK VNEDASGDVT ALQQEIRKLK VQLTSLLKNH DSCGALSDCI SSLEESRYSG TCKVAGETRQ DKCHCQVKNM NDNMIGALRR EKIAESALQK
0601: SEAEIERIDC LVRDMEEDAK RIKIMLNLRE EKVGEMEFCT SGSLMTKECL IEENKTLKGE IKLLRDSIDK NPELTRSALE NTKLREQLQR YQKFYEHGER
0701: EALLAEVTGL RDQLLDVLEA KDESFSKHVM KENEMEKEFE DCRNMNSSLI RELDEIQAGL GRYLNFDQIQ SNVVASSTRG AEQAETMPTI SEIQEEVAIS
0801: HSKNYDRGAL VKTDEGIDRS ILQFKLGKLM KDLEEARTLN CKYEKDHKSQ LSQQEDIEVV REQVETETAR TILELQEEVI ALQSEFQRRI CNLTEENQSI
0901: KDTITARESE IRALNQDWEK ATLELTNFIV AGSKSIKNAS TQIESIICSF PQVNAWIGDY VEKAAKNCIK KEETILLLQK SLEDARILVA EMNLKLNSLK
1001: GATIALNEFQ LGGNAATTEE AFNLNNDVDR MSDEVDTLES NFKANQYSIL KTERHAEAAL AVTKWLSDSR DQHQMMEKVQ DQSVKEFGTL SSISASLSAE
1101: GNADISLSRD GHLSDATYPK GDELSTSSSD FSNCRWQHDC ALNVKCQGVS SSESDAQESN NKITSAALIA KNGSAHSVYC GEGRQSVEKP LTIMMGREET
1201: EYKCSKPLSS GVYMGLMQRM DPVRTFFDRF EEVNATMKEA DLTICELVKA NEKSNSVTEM WLQTHEELIS KEKNLMDDLE QVKSILSACE EEKQVLLNQT
1301: HTTLADMENS VSLLEEYFQE MKRGVEETVE ALFSHARLAG KELLQLISNS RPSLEQIASE FMEREFTMYA TYQCHIGKLI DQILDQRKQV ITPNLSGQET
1401: NQSVKINAIG YNAEDEVTKK QSREEIVTGL ENDEVVQSHE SLLYENLYLK KELERKEALF EGLLFDFRLL QESASNKRDI KNEMDELFDA LCKVQLELEL
1501: KASQVHELFV HNENLENCSI DLKTALFTSQ SDLEQAKQRI QILAEQNDEL RALVSDLCKE KAAAEEGLDE QRDLVNRLEK EILHLTTTAE KQLLSAVKSI
1601: KENLKKTSDE KDQIVDEICS LNNKLELAYA IADEKEAIAV EAHQESEASK IYAEQKEEEV KILEISVEEL ERTINILERR VYDMDEEVKR HRTTQDSLET
1701: ELQALRQRLF RFENFTGTMV TTNESTEEYK SHISRSTGLQ GAHSQIQVLQ KEVAEQTKEI KQLKEYISEI LLHSEAQSSA YQEKYKTLEV MIRDFKLEDS
1801: SSSAAETISH KTEKSSTRSR GSSSPFRCIV GLVQQMKLEK DQELTMARVR VEELESLLAV KQKEICTLNT RIAAADSMTH DVIRDLLGVK MDITSYAELI
1901: DQHQVQRVVE KAQQHAEEIL SKEQEVMNLK RHIDYLFKDR ESCMSELNKK DTDVLATQIS LDQLQERVQL LSMQNEMLKN DKSNLLRKLA ELDRTVHNAQ
2001: ASNHRVPQTT KDTASFKLAD TDYTKRLENA QKLLSHANNE LAKYRKTSNN HPSTRTQGQS SGTRYR
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)