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AT3G14270.1
Subcellular Consensus
(Prediction and Experimental)
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SUBAcon:
vacuole 0.969
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
  • PMID:24807078 (2014): endoplasmic reticulum
  • PMID:24807078 (2014): plant-type vacuole
  • PMID:21173023 (2011): Golgi trans-Golgi network
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no PPI data
Description (TAIR10) protein_coding : phosphatidylinositol-4-phosphate 5-kinase family protein
Curator
Summary (TAIR10)
Encodes a protein that is predicted to act as a 1-phosphatidylinositol-3-phosphate (PtdIns3P) 5-kinase based on its homology to Fab1 from yeast. It contains an FYVE domain required for binding to PtdIns3P-containing membranes in yeast, as well as a Cpn60_TCP1 homology domain plus a kinase domain. fab1a/fab1b pollen grains not viable and have defective vacuolar organization.
Computational
Description (TAIR10)
FORMS APLOID AND BINUCLEATE CELLS 1B (FAB1B); CONTAINS InterPro DOMAIN/s: Chaperonin Cpn60/TCP-1 (InterPro:IPR002423), Zinc finger, FYVE-type (InterPro:IPR000306), Zinc finger, FYVE-related (InterPro:IPR017455), Zinc finger, FYVE/PHD-type (InterPro:IPR011011), Phosphatidylinositol-4-phosphate 5-kinase, core (InterPro:IPR002498); BEST Arabidopsis thaliana protein match is: 1-phosphatidylinositol-4-phosphate 5-kinases;zinc ion binding;1-phosphatidylinositol-3-phosphate 5-kinases (TAIR:AT4G33240.2); Has 8765 Blast hits to 8134 proteins in 458 species: Archae - 587; Bacteria - 13; Metazoa - 3836; Fungi - 1744; Plants - 978; Viruses - 3; Other Eukaryotes - 1604 (source: NCBI BLink).
Protein Annotations
BioCyc:ARA:AT3G14270-MONOMEREC:2.7.1.150eggNOG:COG0459eggNOG:COG5253
eggNOG:KOG0230EMBL:AB022220EMBL:AK228922EMBL:CP002686
EnsemblPlants:AT3G14270EnsemblPlants:AT3G14270.1entrez:820647Gene3D:3.30.40.10
Gene3D:3.30.800.10Gene3D:3.30.810.10Gene3D:3.50.7.10GeneID:820647
Genevisible:Q9LUM0GO:GO:0000285GO:GO:0005524GO:GO:0005739
GO:GO:0005768GO:GO:0007033GO:GO:0009555GO:GO:0010008
GO:GO:0010256GO:GO:0046854GO:GO:0046872GO:GO:0090332
Gramene:AT3G14270.1hmmpanther:PTHR11353hmmpanther:PTHR11353:SF93HOGENOM:HOG000241144
InParanoid:Q9LUM0InterPro:IPR000306InterPro:IPR002423InterPro:IPR002498
InterPro:IPR011011InterPro:IPR013083InterPro:IPR017455InterPro:IPR027409
InterPro:IPR027483InterPro:IPR027484iPTMnet:Q9LUM0KEGG:ath:AT3G14270
KO:K00921ncoils:CoilOMA:RDECEASPaxDb:Q9LUM0
Pfam:PF00118Pfam:PF01363Pfam:PF01504Pfam:Q9LUM0
Pfscan:PS50178Pfscan:PS51455PhylomeDB:Q9LUM0PRIDE:Q9LUM0
PRO:PR:Q9LUM0PROSITE:PS50178PROSITE:PS51455ProteinModelPortal:Q9LUM0
Proteomes:UP000006548Reactome:R-ATH-1660514Reactome:R-ATH-1660516Reactome:R-ATH-1660517
RefSeq:NP_188044.1SMART:SM00064SMART:SM00330SMR:Q9LUM0
STRING:3702.AT3G14270.1SUPFAM:SSF52029SUPFAM:SSF56104SUPFAM:SSF57903
TAIR:AT3G14270tair10-symbols:FAB1BUniGene:At.23226UniGene:At.71114
UniProt:Q9LUM0
Coordinates (TAIR10) chr3:+:4754624..4761185
Molecular Weight (calculated) 200842.00 Da
IEP (calculated) 5.72
GRAVY (calculated) -0.51
Length 1791 amino acids
Sequence (TAIR10)
(BLAST)
0001: MGTRDSNNRT FSEIVGLIKS WLPWRSEPAT VSRDFWMPDQ SCRVCYECDC QFTLINRRHH CRHCGRVFCG KCTANSIPFA PSDLRTPRED WERIRVCNYC
0101: FRQWEQGDGG PHVSNITELS TSPSETSLLS SKTSTTANSS SFALGSMPGL IGLNQRVHHG SDVSLHGVSS METSVTKQGK ETSRRSSFIA TDVEDPSRFA
0201: LNSIRSDDEY DEYGAYQTDI ETSHSPRANE YYGPMEYNGM GIDDVPCKHL GGETADQKSL SGSPLIHQCL ESLIREGSEQ FQKKSEHDGR DECEASSPAD
0301: ISDDQVVEPV DFENNGLLWV PPEPENEEDE RESALFDEED NEGDASGEWG YLRPSTSFGS GEYRGEDRTT EEHKKAMKNV VDGHFRALLA QLLQVENISV
0401: SDEEGKESWL EIITSLSWEA ANLLKPDMSK SGGMDPGGYV KVKCLASGFR HDSMVVKGVV CKKNVVNRRM STKIEKARLL ILGGGLEYQR VSNQLSSFDT
0501: LLQQEKDHLK MAVAKIHAER PNILLVEKSV SRFAQEYLLA KDISLVLNIK RPLLDRIARC TGAQIIPSVD HLSSQKLGYC ENFRVDRYPE EHGSTGQVGK
0601: KVVKTLMYFE HCPKPLGFTI LLRGANEDEL KKVKHVVQYG VFAAYHLALE TSFLADEGAS PELPLNSPIT VALPDKSTSI ERSISTVPGF TVSTYEKSPT
0701: MLSCAEPQRA NSVPVSELLS TTTNLSIQKD IPPIPYGSGW QAREINPSFV FSRHNISLNL PDRVIESRNS DLSGRSVPVD TPADKSNPIV VADETTNNSL
0801: HLSGQGFVRK SSQIGTSIMV ENQDNGSELT IAQQQNNEKP KETQSQKEEF PPSPSDHQSI LVSLSSRSVW KGTVCERSHL FRIKYYGSFD KPLGRFLRDH
0901: LFDQSYRCRS CEMPSEAHVH CYTHRQGSLT ISVKKLQDYL LPGEKEGKIW MWHRCLRCPR LNGFPPATLR VVMSDAAWGL SFGKFLELSF SNHAAASRVA
1001: CCGHSLHRDC LRFYGFGNMV ACFRYATIDV HSVYLPPSIL SFNYENQDWI QRETDEVIER AELLFSEVLN AISQIAEKGF RRRIGELEEV LQKEKAEFEE
1101: NMQKILHREV NEGQPLVDIL ELYRIHRQLL FQSYMWDHRL INASTLHKLE NSDDTKREEN EKPPLAKSQT LPEMNAGTNS LLTGSEVNLN PDGDSTGDTG
1201: SLNNVQKEAD TNSDLYQEKD DGGEVSPSKT LPDTSYPLEN KVDVRRTQSD GQIVMKNLSA TLDAAWIGER QTSVEIPTNN KVSLPPSTMS NSSTFPPISE
1301: GLMPIDLPEQ QNEFKVAYPV SPALPSKNYE NSEDSVSWLS VPFLNFYRSI NKNFLLSSQK LDTFGEHSPI YISSFREAEL QGGPRLLLPV GLNDIVVPVY
1401: DDEPTSMIAY ALMSPEYQRQ TSAEGESLVS YPSELNIPRP VDDTIFDPSR SNGSVDESIL SISSSRSTSL LDPLSYTKAL HARVSYGEDG TLGKVKYTVT
1501: CYYAKRFEAL RGICLPSELE YIRSLSRCKK WGAQGGKSNV FFAKTLDDRF IIKQVTKTEL ESFIKFAPAY FKYLSESIST KSPTCLAKIL GIYQVATKQL
1601: KSGKETKMDV LIMENLLFGR TVKRLYDLKG SSRARYNPDS SGSNKVLLDQ NLIEAMPTSP IFVGNKAKRL LERAVWNDTA FLALGDVMDY SLLVGVDEEK
1701: NELVLGIIDF LRQYTWDKHL ESWVKFTGIL GGPKNEAPTV ISPKQYKRRF RKAMTTYFLM VPDQWSPPNV VANNSKSDQP EETSQAGTQA E
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)