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AT3G12120.1
Subcellular Consensus
(Prediction and Experimental)

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SUBAcon:
endoplasmic reticulum 1.000
ASURE: endoplasmic reticulum
What is SUBAcon?
What is ASURE?
SUBAcon computations
Experimental Localisations and PPI
FP MS/MS PPI
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no PPI data
Description (TAIR10) protein_coding : fatty acid desaturase 2
Curator
Summary (TAIR10)
Major enzyme responsible for the synthesis of 18:2 fatty acids in the endoplasmic reticulum. Contains His-rich motifs, which contribute to the interaction with the electron donor cytochrome b5. Mutations in this gene suppress the low temperature-induced phenotype of Arabidopsis tocopherol-deficient mutant vte2.
Computational
Description (TAIR10)
fatty acid desaturase 2 (FAD2); FUNCTIONS IN: omega-6 fatty acid desaturase activity, delta12-fatty acid dehydrogenase activity; INVOLVED IN: oxidation reduction, lipid metabolic process; LOCATED IN: endoplasmic reticulum; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Protein of unknown function DUF3474 (InterPro:IPR021863), Fatty acid desaturase, type 1 (InterPro:IPR005804); BEST Arabidopsis thaliana protein match is: fatty acid desaturase 3 (TAIR:AT2G29980.1); Has 2431 Blast hits to 2431 proteins in 654 species: Archae - 0; Bacteria - 821; Metazoa - 31; Fungi - 266; Plants - 965; Viruses - 0; Other Eukaryotes - 348 (source: NCBI BLink).
Protein Annotations
BioCyc:ARA:GQT-417-MONOMERBioCyc:MetaCyc:AT3G12120-MONOMERBioGrid:5721EC:1.14.19.22EC:1.14.19.6eggNOG:COG3239eggNOG:ENOG410IFN9
EMBL:AC069473EMBL:AP002063EMBL:AY039572EMBL:AY142057EMBL:CP002686EMBL:L26296EnsemblPlants:AT3G12120
EnsemblPlants:AT3G12120.1EnsemblPlants:AT3G12120.2entrez:820387GeneID:820387Genevisible:P46313GO:GO:0005789GO:GO:0006636
GO:GO:0016021GO:GO:0016717GO:GO:0045485Gramene:AT3G12120.1Gramene:AT3G12120.2gramene_pathway:1.14.19.6gramene_pathway:PWY-5995
gramene_plant_reactome:1119300gramene_plant_reactome:6874304gramene_plant_reactome:6874644gramene_plant_reactome:6875243gramene_plant_reactome:6875610gramene_plant_reactome:6875746gramene_plant_reactome:6875805
gramene_plant_reactome:6876243gramene_plant_reactome:6876571hmmpanther:PTHR32100hmmpanther:PTHR32100:SF13HOGENOM:HOG000201905InParanoid:P46313InterPro:IPR005804
InterPro:IPR021863iPTMnet:P46313KEGG:ath:AT3G12120KO:K10256OMA:LWPSIWAPaxDb:P46313Pfam:P46313
Pfam:PF00487Pfam:PF11960PhylomeDB:P46313PRIDE:P46313PRO:PR:P46313ProteinModelPortal:P46313Proteomes:UP000006548
RefSeq:NP_001078140.1RefSeq:NP_187819.1SMR:P46313STRING:3702.AT3G12120.1SwissLipids:SLP:000000808TAIR:AT3G12120tair10-symbols:FAD2
TMHMM:TMhelixUniGene:At.23898UniGene:At.50826UniGene:At.66993UniPathway:UPA00658UniProt:P46313
Coordinates (TAIR10) chr3:-:3860592..3861743
Molecular Weight (calculated) 44050.00 Da
IEP (calculated) 8.24
GRAVY (calculated) -0.09
Length 383 amino acids
Sequence (TAIR10)
(BLAST)
001: MGAGGRMPVP TSSKKSETDT TKRVPCEKPP FSVGDLKKAI PPHCFKRSIP RSFSYLISDI IIASCFYYVA TNYFSLLPQP LSYLAWPLYW ACQGCVLTGI
101: WVIAHECGHH AFSDYQWLDD TVGLIFHSFL LVPYFSWKYS HRRHHSNTGS LERDEVFVPK QKSAIKWYGK YLNNPLGRIM MLTVQFVLGW PLYLAFNVSG
201: RPYDGFACHF FPNAPIYNDR ERLQIYLSDA GILAVCFGLY RYAAAQGMAS MICLYGVPLL IVNAFLVLIT YLQHTHPSLP HYDSSEWDWL RGALATVDRD
301: YGILNKVFHN ITDTHVAHHL FSTMPHYNAM EATKAIKPIL GDYYQFDGTP WYVAMYREAK ECIYVEPDRE GDKKGVYWYN NKL
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)