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AT3G10800.1
Subcellular Consensus
(Prediction and Experimental)

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SUBAcon:
endoplasmic reticulum 1.000
What is SUBAcon?
What is ASURE?
SUBAcon computations
Experimental Localisations and PPI
FP MS/MS PPI
  • PMID:23624714 (2013): endoplasmic reticulum
  • PMID:23624714 (2013): nucleus
  • PMID:18634751 (2008): endoplasmic reticulum
  • PMID:18156219 (2007): endoplasmic reticulum endoplasmic reticulum membrane
  • PMID:18156219 (2007): nucleus
SUBAcon links
AGI-AGI relationships
Coexpression PPI
Description (TAIR10) protein_coding : Basic-leucine zipper (bZIP) transcription factor family protein
Curator
Summary (TAIR10)
Encodes bZIP28, a putative membrane-tethered transcriptional factor. Up-regulated in response to heat; a bZIP28 null mutant has a heat-sensitive phenotype. bZIP28 has a similar domain structure to the mammalian ATF6 protein involved in the unfolded protein response (UPR), and shares a bZIP domain, transmembrane domain, and a canonical S1P cleavage site. The bZIP28 seems to be glycosylated in vivo. bZIP28 does not appear to be transcriptionally up-regulated by UPR-inducing tunicamycin (TM) treatment. But, the expression level of three UPR-related genes is reduced in TM-treated zip28 mutants relative to wild type seedlings. And several UPR genes are transcriptionally upregulated when an N-terminal portion of the bZIP28 protein is expressed using the 35S promoter. A myc:bZIP28 fusion protein appears to be cleaved, likely at a canonical S2 cleavage site, following a TM treatment or a DTT stress-inducing treatment, but not a salt treatment. A portion of the mGFP:bZIP28 protein present in root cells appears to translocate from the cytoplasm and ER to the nucleus following TM treatment.
Computational
Description (TAIR10)
BZIP28; CONTAINS InterPro DOMAIN/s: Basic-leucine zipper (bZIP) transcription factor (InterPro:IPR004827), bZIP transcription factor, bZIP-1 (InterPro:IPR011616); BEST Arabidopsis thaliana protein match is: Basic-leucine zipper (bZIP) transcription factor family protein (TAIR:AT2G40950.1); Has 1906 Blast hits to 1391 proteins in 215 species: Archae - 0; Bacteria - 248; Metazoa - 700; Fungi - 222; Plants - 463; Viruses - 4; Other Eukaryotes - 269 (source: NCBI BLink).
Protein Annotations
eggNOG:ENOG410IIGCeggNOG:ENOG410XUDSEMBL:AC011708EMBL:AK226928EMBL:BT002502EMBL:CP002686EnsemblPlants:AT3G10800
EnsemblPlants:AT3G10800.1entrez:820249GeneID:820249Genevisible:Q9SG86GO:GO:0000139GO:GO:0003700GO:GO:0005634
GO:GO:0005635GO:GO:0005654GO:GO:0005737GO:GO:0005783GO:GO:0005789GO:GO:0006351GO:GO:0006986
GO:GO:0006990GO:GO:0009408GO:GO:0016020GO:GO:0016021GO:GO:0030968GO:GO:0034976GO:GO:0043565
GO:GO:0048471Gramene:AT3G10800.1hmmpanther:PTHR22952hmmpanther:PTHR22952:SF17HOGENOM:HOG000241437InterPro:IPR004827iPTMnet:Q9SG86
KEGG:ath:AT3G10800ncoils:CoilOMA:KSMNATIPaxDb:Q9SG86Pfam:PF00170Pfam:Q9SG86Pfscan:PS50217
PRIDE:Q9SG86PRO:PR:Q9SG86PROSITE:PS50217ProteinModelPortal:Q9SG86Proteomes:UP000006548RefSeq:NP_187691.1SMART:SM00338
SMR:Q9SG86STRING:3702.AT3G10800.1SUPFAM:SSF57959TAIR:AT3G10800tair10-symbols:BZIP28TMHMM:TMhelixUniGene:At.27487
UniProt:Q9SG86
Coordinates (TAIR10) chr3:+:3379326..3381430
Molecular Weight (calculated) 73436.40 Da
IEP (calculated) 6.41
GRAVY (calculated) -0.48
Length 675 amino acids
Sequence (TAIR10)
(BLAST)
001: MTESTSVVAP PPEIPNLNPS MFSESDLFSI PPLDPLFLSD SDPISMDAPI SDLDFLLDDE NGDFADFDFS FDNSDDFFDF DLSEPAVVIP EEIGNNRSNL
101: DSSENRSGDG GLEGRSESVH SQVSSQGSKT FVSDTVDASS SPESSNHQKS SVSKRKKENG DSSGELRSCK YQKSDDKSVA TNNEGDDDDD KRKLIRQIRN
201: RESAQLSRLR KKQQTEELER KVKSMNATIA ELNGKIAYVM AENVALRQQM AVASGAPPMN PYMAAPPLPY QWMPYPPYPV RGYGSQTPLV PIPKLNPKPV
301: SSCRPKKAES KKNEGKSKLK KVASISFIGI LFFVFLFGTL VPFMNVNFGG ERGSFGGLSK YDGHRYYDEH KGRVLMVGDG SDVRRNSGIS EGNIHSSRIS
401: HGERDSCGGV DYNAHPKVEG RPSSLSNASD PLFASLYVPR NDGLVKIDGN LIIHSVLASE KARGLGKKNI TETVKTKEPD LTIPGALSSA LAVPGVRGNA
501: AMLPHSTALS SEGKRLHQWF HEGGSGPLMD YSMCTEVFQF DIAPGAIVPS SVSSISAEHL QNVTTHGKRM KNRRILEGLP VSLVASELNI TGTQPNKDAQ
601: NKTFNGNTNK PTSSSSMVVS VLLDPREVVD SETDRVVPPN PKSLSRIFVV VLLDSVKYVT YSCVLPRSGL HLVAT
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)