suba logo
AT3G08040.1
Subcellular Consensus
(Prediction and Experimental)

min: heatmap :max

.
SUBAcon:
plasma membrane 0.994
What is SUBAcon?
What is ASURE?
SUBAcon computations
Experimental Localisations and PPI
FP MS/MS PPI
SUBAcon links
AGI-AGI relationships
Coexpression PPI
Description (TAIR10) protein_coding : MATE efflux family protein
Curator
Summary (TAIR10)
Encodes a member of the MATE (multidrug and toxin efflux family), expressed in roots but not shoots. Mutants accumulate excess iron, manganese and zinc, and express root Fe(III) chelatase activity even under iron sufficiency conditions. FRD3 is likely to function in root xylem loading of an iron chelator or other factor necessary for efficient iron uptake out of the xylem or apoplastic space and into leaf cells.
Computational
Description (TAIR10)
FERRIC REDUCTASE DEFECTIVE 3 (FRD3); FUNCTIONS IN: antiporter activity, transporter activity; INVOLVED IN: cellular iron ion homeostasis; LOCATED IN: plasma membrane, membrane; EXPRESSED IN: 20 plant structures; EXPRESSED DURING: 4 anthesis, F mature embryo stage, petal differentiation and expansion stage, D bilateral stage; CONTAINS InterPro DOMAIN/s: Multi antimicrobial extrusion protein MatE (InterPro:IPR002528); BEST Arabidopsis thaliana protein match is: MATE efflux family protein (TAIR:AT1G51340.2); Has 16442 Blast hits to 16241 proteins in 2243 species: Archae - 390; Bacteria - 12800; Metazoa - 108; Fungi - 151; Plants - 401; Viruses - 0; Other Eukaryotes - 2592 (source: NCBI BLink).
Protein Annotations
BioGrid:5330eggNOG:COG0534eggNOG:KOG1347EMBL:AC013483EMBL:AC074395EMBL:AF448231EMBL:AY056439
EMBL:AY057517EMBL:AY133652EMBL:BT006370EMBL:CP002686EnsemblPlants:AT3G08040EnsemblPlants:AT3G08040.1EnsemblPlants:AT3G08040.2
entrez:819995GeneID:819995Genevisible:Q9SFB0GO:GO:0005215GO:GO:0005886GO:GO:0006855GO:GO:0006879
GO:GO:0009737GO:GO:0015137GO:GO:0015238GO:GO:0015297GO:GO:0015746GO:GO:0016021GO:GO:0030001
GO:GO:0046873GO:GO:0071281GO:GO:0071369GO:GO:0071732Gramene:AT3G08040.1Gramene:AT3G08040.2hmmpanther:PTHR11206
hmmpanther:PTHR11206:SF156HOGENOM:HOG000253153InParanoid:Q9SFB0IntAct:Q9SFB0InterPro:IPR002528iPTMnet:Q9SFB0KEGG:ath:AT3G08040
OMA:PFIANTIPaxDb:Q9SFB0Pfam:PF01554Pfam:Q9SFB0PhylomeDB:Q9SFB0PRIDE:Q9SFB0PRO:PR:Q9SFB0
ProteinModelPortal:Q9SFB0Proteomes:UP000006548RefSeq:NP_001154595.1RefSeq:NP_187461.1SMR:Q9SFB0STRING:3702.AT3G08040.1TAIR:AT3G08040
tair10-symbols:ATFRD3tair10-symbols:FRD3tair10-symbols:MAN1TCDB:2.A.66.1.24TIGRfam:TIGR00797TIGRFAMs:TIGR00797TMHMM:TMhelix
UniGene:At.17333UniProt:Q9SFB0
Coordinates (TAIR10) chr3:-:2566593..2569397
Molecular Weight (calculated) 55949.40 Da
IEP (calculated) 10.18
GRAVY (calculated) 0.61
Length 526 amino acids
Sequence (TAIR10)
(BLAST)
001: MTETGDDLAT VKKPIPFLVI FKDLRHVFSR DTTGREILGI AFPAALALAA DPIASLIDTA FVGRLGAVQL AAVGVSIAIF NQASRITIFP LVSLTTSFVA
101: EEDTMEKMKE EANKANLVHA ETILVQDSLE KGISSPTSND TNQPQQPPAP DTKSNSGNKS NKKEKRTIRT ASTAMILGLI LGLVQAIFLI FSSKLLLGVM
201: GVKPNSPMLS PAHKYLSIRA LGAPALLLSL AMQGIFRGFK DTKTPLFATV VADVINIVLD PIFIFVLRLG IIGAAIAHVI SQYFMTLILF VFLAKKVNLI
301: PPNFGDLQFG RFLKNGLLLL ARTIAVTFCQ TLAAAMAARL GTTPMAAFQI CLQVWLTSSL LNDGLAVAGQ AILACSFAEK DYNKVTAVAS RVLQMGFVLG
401: LGLSVFVGLG LYFGAGVFSK DPAVIHLMAI GIPFIAATQP INSLAFVLDG VNFGASDFAY TAYSMVGVAA ISIAAVIYMA KTNGFIGIWI ALTIYMALRA
501: ITGIARMATG TGPWRFLRGR SSSSSS
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)