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AT3G06860.1
Subcellular Consensus
(Prediction and Experimental)

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SUBAcon:
peroxisome 1.000
ASURE: peroxisome
What is SUBAcon?
What is ASURE?
SUBAcon computations
Experimental Localisations and PPI
FP MS/MS PPI
  • PMID:27943495 (2017): mitochondrion
  • PMID:27122571 (2016): mitochondrion
  • PMID:26572690 (2016): extracellular region plant-type cell wall
  • PMID:25900983 (2015): Golgi trans-Golgi network
  • PMID:25900983 (2015): Golgi trans-Golgi network multivesicular body
  • PMID:24727099 (2014): mitochondrion
  • PMID:24130194 (2013): peroxisome
  • PMID:23396599 (2013): nucleus nuclear envelope nuclear inner membrane
  • PMID:21433285 (2011): plasma membrane
  • PMID:19334764 (2009): plasma membrane
  • PMID:19329564 (2009): peroxisome
  • PMID:18931141 (2008): peroxisome
  • PMID:17951448 (2007): peroxisome
  • PMID:15496452 (2005): nucleus
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no PPI data
Description (TAIR10) protein_coding : multifunctional protein 2
Curator
Summary (TAIR10)
Encodes a multifunctional protein. Involved in peroxisomal fatty acid beta oxidation. Loss-of-function mutant lacks hydroxyacyl-CoA dehydrogenase activity and have reduced levels of long-chain enoyl-CoA hydratase activity. The mutant has fewer but larger peroxisomes.
Computational
Description (TAIR10)
multifunctional protein 2 (MFP2); FUNCTIONS IN: enoyl-CoA hydratase activity, 3-hydroxyacyl-CoA dehydrogenase activity; INVOLVED IN: fatty acid beta-oxidation; LOCATED IN: nucleolus, cell wall, peroxisome; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Enoyl-CoA hydratase/isomerase, conserved site (InterPro:IPR018376), 3-hydroxyacyl-CoA dehydrogenase, conserved site (InterPro:IPR006180), 6-phosphogluconate dehydrogenase, C-terminal-like (InterPro:IPR008927), Dehydrogenase, multihelical (InterPro:IPR013328), NAD(P)-binding domain (InterPro:IPR016040), 3-hydroxyacyl-CoA dehydrogenase, NAD binding (InterPro:IPR006176), Crotonase, core (InterPro:IPR001753), 3-hydroxyacyl-CoA dehydrogenase, C-terminal (InterPro:IPR006108); BEST Arabidopsis thaliana protein match is: Enoyl-CoA hydratase/isomerase family (TAIR:AT4G29010.1); Has 46309 Blast hits to 45272 proteins in 2450 species: Archae - 810; Bacteria - 29664; Metazoa - 2011; Fungi - 1039; Plants - 666; Viruses - 0; Other Eukaryotes - 12119 (source: NCBI BLink).
Protein Annotations
BioCyc:ARA:AT3G06860-MONOMERBioCyc:MetaCyc:AT3G06860-MONOMERBioGrid:5205DisProt:DP00654EC:1.1.1.35EC:4.2.1.17EC:5.1.2.3
EC:5.3.3.8eggNOG:COG1024eggNOG:COG1250eggNOG:KOG1683EMBL:AC016827EMBL:AF123254EMBL:AY062621
EMBL:CP002686EnsemblPlants:AT3G06860EnsemblPlants:AT3G06860.1entrez:819870EvolutionaryTrace:Q9ZPI5Gene3D:1.10.1040.10Gene3D:3.40.50.720
Gene3D:3.90.226.10GeneID:819870Genevisible:Q9ZPI5GO:GO:0003857GO:GO:0004165GO:GO:0004300GO:GO:0005618
GO:GO:0005730GO:GO:0005777GO:GO:0006635GO:GO:0008692GO:GO:0009506GO:GO:0009514GO:GO:0016508
Gramene:AT3G06860.1gramene_pathway:1.1.1.35gramene_pathway:4.2.1.116gramene_pathway:4.2.1.17gramene_pathway:4.2.1.55gramene_pathway:ILEUDEG-PWYgramene_pathway:LYSINE-DEG2-PWY
gramene_pathway:PWY-3941gramene_pathway:PWY-5136gramene_pathway:PWY-5138gramene_pathway:VALDEG-PWYhmmpanther:PTHR23309hmmpanther:PTHR23309:SF23HOGENOM:HOG000261347
InParanoid:Q9ZPI5InterPro:IPR001753InterPro:IPR006108InterPro:IPR006176InterPro:IPR006180InterPro:IPR008927InterPro:IPR013328
InterPro:IPR016040InterPro:IPR018376InterPro:IPR029045iPTMnet:Q9ZPI5KEGG:00062+4.2.1.17+1.1.1.35KEGG:00071+4.2.1.17+1.1.1.35KEGG:00071+5.1.2.3+4.2.1.17+1.1.1.35
KEGG:00120+1.1.1.35KEGG:00280+4.2.1.17+1.1.1.35KEGG:00281+4.2.1.17+1.1.1.35KEGG:00310+4.2.1.17+1.1.1.35KEGG:00360+4.2.1.17KEGG:00362+4.2.1.17+1.1.1.35KEGG:00380+4.2.1.17+1.1.1.35
KEGG:00410+4.2.1.17KEGG:00592+4.2.1.17KEGG:00623+1.1.1.35KEGG:00627+4.2.1.17KEGG:00640+4.2.1.17KEGG:00650+4.2.1.17+1.1.1.35KEGG:00650+5.1.2.3+4.2.1.17+1.1.1.35
KEGG:00720+4.2.1.17+1.1.1.35KEGG:00903+4.2.1.17KEGG:00930+4.2.1.17+1.1.1.35KEGG:ath:AT3G06860KO:K10527OMA:LEWALACPaxDb:Q9ZPI5
PDB:2WTBPDBsum:2WTBPfam:PF00378Pfam:PF00725Pfam:PF02737Pfam:Q9ZPI5PhylomeDB:Q9ZPI5
PRIDE:Q9ZPI5PRO:PR:Q9ZPI5PROSITE:PS00067PROSITE:PS00166ProteinModelPortal:Q9ZPI5Proteomes:UP000006548RefSeq:NP_187342.1
scanprosite:PS00067scanprosite:PS00166SMR:Q9ZPI5STRING:3702.AT3G06860.1SUPFAM:SSF48179SUPFAM:SSF51735SUPFAM:SSF52096
SwissLipids:SLP:000000867TAIR:AT3G06860tair10-symbols:ATMFP2tair10-symbols:MFP2UniGene:At.24386UniPathway:UPA00659UniProt:Q9ZPI5
Coordinates (TAIR10) chr3:+:2161926..2166009
Molecular Weight (calculated) 78844.70 Da
IEP (calculated) 9.68
GRAVY (calculated) 0.01
Length 725 amino acids
Sequence (TAIR10)
(BLAST)
001: MDSRTKGKTV MEVGGDGVAV ITLINPPVNS LSFDVLYNLK SNYEEALSRN DVKAIVITGA KGRFSGGFDI SGFGEMQKGN VKEPKAGYIS IDIITDLLEA
101: ARKPSVAAID GLALGGGLEL AMACHARISA PAAQLGLPEL QLGVIPGFGG TQRLPRLVGL TKALEMILTS KPVKAEEGHS LGLIDAVVPP AELVTTARRW
201: ALDIVGRRKP WVSSVSKTDK LPPLGEAREI LTFAKAQTLK RAPNMKHPLM CLDAIEVGIV SGPRAGLEKE AEVASQVVKL DTTKGLIHVF FSQRGTAKVP
301: GVTDRGLVPR KIKKVAIIGG GLMGSGIATA LILSNYPVIL KEVNEKFLEA GIGRVKANLQ SRVRKGSMSQ EKFEKTMSLL KGSLDYESFR DVDMVIEAVI
401: ENISLKQQIF ADLEKYCPQH CILASNTSTI DLNKIGERTK SQDRIVGAHF FSPAHIMPLL EIVRTNHTSA QVIVDLLDVG KKIKKTPVVV GNCTGFAVNR
501: MFFPYTQAAM FLVECGADPY LIDRAISKFG MPMGPFRLCD LVGFGVAIAT ATQFIENFSE RTYKSMIIPL MQEDKRAGEA TRKGFYLYDD KRKAKPDPEL
601: KKYIEKARSI SGVKLDPKLA NLSEKDIIEM TFFPVVNEAC RVFAEGIAVK AADLDIAGIM GMGFPPYRGG IMFWADSIGS KYIYSRLDEW SKAYGEFFKP
701: CAFLAERGSK GVLLSAPVKQ ASSRL
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)