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AT2G47000.1
Subcellular Consensus
(Prediction and Experimental)

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SUBAcon:
plasma membrane 1.000
ASURE: plasma membrane
What is SUBAcon?
What is ASURE?
SUBAcon computations
Experimental Localisations and PPI
FP MS/MS PPI
  • PMID:22492845 (2012): Golgi trans-Golgi network multivesicular body
  • PMID:22492845 (2012): plasma membrane
  • PMID:26781341 (2016): plasma membrane
  • PMID:26091700 (2015): plasma membrane
  • PMID:25900983 (2015): Golgi
  • PMID:25900983 (2015): Golgi trans-Golgi network
  • PMID:25900983 (2015): Golgi trans-Golgi network multivesicular body
  • PMID:25641898 (2015): plasma membrane
  • PMID:24361574 (2014): plastid plastid stroma
  • PMID:23990937 (2013): plasma membrane
  • PMID:23903016 (2013): plant-type vacuole plant-type vacuole membrane
  • PMID:22923678 (2012): plasma membrane
  • PMID:22318864 (2012): plasma membrane
  • PMID:21826108 (2012): Golgi trans-Golgi network multivesicular body
  • PMID:21433285 (2011): plasma membrane
  • PMID:20843791 (2010): plasma membrane
  • PMID:20374526 (2010): plasma membrane
  • PMID:19334764 (2009): plasma membrane
  • PMID:17317660 (2007): plasma membrane
  • PMID:16618929 (2006): plasma membrane
  • PMID:15308754 (2004): plasma membrane
  • PMID:14506206 (2003): plasma membrane
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no PPI data
Description (TAIR10) protein_coding : ATP binding cassette subfamily B4
Curator
Summary (TAIR10)
Multidrug resistance P-glycoprotein (MDR/PGP) subfamily of ABC transporters. Functions in the basipetal redirection of auxin from the root tip. Exhibits apolar plasma membrane localization in the root cap and polar localization in tissues above.
Computational
Description (TAIR10)
ATP binding cassette subfamily B4 (ABCB4); FUNCTIONS IN: xenobiotic-transporting ATPase activity, ATPase activity, coupled to transmembrane movement of substances; INVOLVED IN: in 8 processes; LOCATED IN: plasma membrane, membrane; EXPRESSED IN: 14 plant structures; EXPRESSED DURING: 4 anthesis, petal differentiation and expansion stage; CONTAINS InterPro DOMAIN/s: ATPase, AAA+ type, core (InterPro:IPR003593), ABC transporter-like (InterPro:IPR003439), ABC transporter, transmembrane domain, type 1 (InterPro:IPR011527), ABC transporter integral membrane type 1 (InterPro:IPR017940), ABC transporter, transmembrane domain (InterPro:IPR001140), ABC transporter, conserved site (InterPro:IPR017871); BEST Arabidopsis thaliana protein match is: P-glycoprotein 21 (TAIR:AT3G62150.1); Has 844144 Blast hits to 390751 proteins in 4168 species: Archae - 14748; Bacteria - 659498; Metazoa - 17847; Fungi - 13026; Plants - 10001; Viruses - 45; Other Eukaryotes - 128979 (source: NCBI BLink).
Protein Annotations
BioCyc:ARA:AT2G47000-MONOMERBioGrid:4649eggNOG:COG1132eggNOG:KOG0055EMBL:AC004411EMBL:CP002685EnsemblPlants:AT2G47000
EnsemblPlants:AT2G47000.1entrez:819314Gene3D:3.40.50.300GeneID:819314Genevisible:O80725GO:GO:0005524GO:GO:0005886
GO:GO:0006855GO:GO:0008559GO:GO:0009506GO:GO:0009630GO:GO:0009733GO:GO:0009734GO:GO:0009735
GO:GO:0009926GO:GO:0010315GO:GO:0010328GO:GO:0010329GO:GO:0010540GO:GO:0016020GO:GO:0016021
GO:GO:0042908GO:GO:0048767GO:GO:0060919Gramene:AT2G47000.1hmmpanther:PTHR24221hmmpanther:PTHR24221:SF205InParanoid:O80725
InterPro:IPR003439InterPro:IPR003593InterPro:IPR011527InterPro:IPR017871InterPro:IPR027417iPTMnet:O80725KEGG:ath:AT2G47000
KO:K05658ncoils:CoilOMA:DANYQNKPaxDb:O80725Pfam:O80725Pfam:PF00005Pfam:PF00664
Pfscan:PS50893Pfscan:PS50929PhylomeDB:O80725PIR:T02187PRIDE:O80725PRO:PR:O80725PROSITE:PS00211
PROSITE:PS50893PROSITE:PS50929ProteinModelPortal:O80725Proteomes:UP000006548RefSeq:NP_182223.1scanprosite:PS00211SMART:SM00382
SMR:O80725STRING:3702.AT2G47000.1SUPFAM:SSF52540SUPFAM:SSF90123SwissPalm:O80725TAIR:AT2G47000tair10-symbols:ABCB4
tair10-symbols:ATPGP4tair10-symbols:MDR4tair10-symbols:PGP4TCDB:3.A.1.201.7TMHMM:TMhelixUniGene:At.43921UniGene:At.67170
UniProt:O80725
Coordinates (TAIR10) chr2:-:19310008..19314750
Molecular Weight (calculated) 139036.00 Da
IEP (calculated) 6.48
GRAVY (calculated) 0.11
Length 1286 amino acids
Sequence (TAIR10)
(BLAST)
0001: MASESGLNGD PNILEEVSET KRDKEEEEEV KKTEKKDEEH EKTKTVPFYK LFAFADSFDF LLMILGTLGS IGNGLGFPLM TLLFGDLIDA FGENQTNTTD
0101: KVSKVALKFV WLGIGTFAAA FLQLSGWMIS GERQAARIRS LYLKTILRQD IAFFDIDTNT GEVVGRMSGD TVLIQDAMGE KVGKAIQLLA TFVGGFVIAF
0201: VRGWLLTLVM LSSIPLLVMA GALLAIVIAK TASRGQTAYA KAATVVEQTI GSIRTVASFT GEKQAISNYN KHLVTAYKAG VIEGGSTGLG LGTLFLVVFC
0301: SYALAVWYGG KLILDKGYTG GQVLNIIIAV LTGSMSLGQT SPCLSAFAAG QAAAYKMFET IERRPNIDSY STNGKVLDDI KGDIELKDVY FTYPARPDEQ
0401: IFRGFSLFIS SGTTVALVGQ SGSGKSTVVS LIERFYDPQA GDVLIDGINL KEFQLKWIRS KIGLVSQEPV LFTASIKDNI AYGKEDATTE EIKAAAELAN
0501: ASKFVDKLPQ GLDTMVGEHG TQLSGGQKQR IAVARAILKD PRILLLDEAT SALDAESERV VQEALDRIMV NRTTVVVAHR LSTVRNADMI AVIHQGKIVE
0601: KGSHTELLKD PEGAYSQLIR LQEEKKSDEN AAEEQKMSSI ESFKQSSLRK SSLGRSLSKG GSSRGNSSRH SFNMFGFPAG IDGNVVQDQE EDDTTQPKTE
0701: PKKVSIFRIA ALNKPEIPVL ILGSISAAAN GVILPIFGIL ISSVIKAFFQ PPKKLKEDTS FWAIIFMVLG FASIIAYPAQ TFFFAIAGCK LVQRIRSMCF
0801: EKVVHMEVGW FDEPENSSGT IGARLSADAA TIRGLVGDSL AQTVQNLSSI LAGLIIAFLA CWQLAFVVLA MLPLIALNGF LYMKFMKGFS ADAKKMYGEA
0901: SQVANDAVGS IRTVASFCAE DKVMNMYSKK CEGPMKNGIR QGIVSGIGFG FSFFVLFSSY AASFYVGARL VDDGKTTFDS VFRVFFALTM AAMAISQSSS
1001: LSPDSSKADV AAASIFAIMD RESKIDPSVE SGRVLDNVKG DIELRHVSFK YPARPDVQIF QDLCLSIRAG KTVALVGESG SGKSTVIALL QRFYDPDSGE
1101: ITLDGVEIKS LRLKWLRQQT GLVSQEPILF NETIRANIAY GKGGDASESE IVSSAELSNA HGFISGLQQG YDTMVGERGI QLSGGQKQRV AIARAIVKDP
1201: KVLLLDEATS ALDAESERVV QDALDRVMVN RTTIVVAHRL STIKNADVIA VVKNGVIVEK GKHDTLINIK DGVYASLVQL HLTAAS
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)