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AT2G46830.1
Subcellular Consensus
(Prediction and Experimental)

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SUBAcon:
nucleus 1.000
ASURE: nucleus
What is SUBAcon?
What is ASURE?
SUBAcon computations
Experimental Localisations and PPI
FP MS/MS PPI
SUBAcon links
AGI-AGI relationships
Coexpression PPI
Description (TAIR10) protein_coding : circadian clock associated 1
Curator
Summary (TAIR10)
Encodes a transcriptional repressor that performs overlapping functions with LHY in a regulatory feedback loop that is closely associated with the circadian oscillator of Arabidopsis. Binds to the evening element in the promoter of TOC1 and represses TOC1 transcription. CCA1 and LHY colocalize in the nucleus and form heterodimers in vivo. CCA1 and LHY function synergistically in regulating circadian rhythms of Arabidopsis.
Computational
Description (TAIR10)
circadian clock associated 1 (CCA1); CONTAINS InterPro DOMAIN/s: SANT, DNA-binding (InterPro:IPR001005), Myb, DNA-binding (InterPro:IPR014778), Homeodomain-like (InterPro:IPR009057), Myb-like DNA-binding domain, SHAQKYF class (InterPro:IPR006447), HTH transcriptional regulator, Myb-type, DNA-binding (InterPro:IPR017930); BEST Arabidopsis thaliana protein match is: Homeodomain-like superfamily protein (TAIR:AT1G01060.3); Has 3942 Blast hits to 2101 proteins in 266 species: Archae - 5; Bacteria - 79; Metazoa - 414; Fungi - 218; Plants - 1144; Viruses - 7; Other Eukaryotes - 2075 (source: NCBI BLink).
Protein Annotations
BioGrid:4631eggNOG:COG5269eggNOG:KOG0724EMBL:AC005310EMBL:AY519511EMBL:BT001096EMBL:BT001105
EMBL:CP002685EMBL:U28422EMBL:U79156EnsemblPlants:AT2G46830EnsemblPlants:AT2G46830.1entrez:819296Gene3D:1.10.10.60
GeneID:819296Genevisible:P92973GO:GO:0003677GO:GO:0003700GO:GO:0005634GO:GO:0006351GO:GO:0007623
GO:GO:0009409GO:GO:0009651GO:GO:0009723GO:GO:0009733GO:GO:0009737GO:GO:0009739GO:GO:0009751
GO:GO:0009753GO:GO:0010243GO:GO:0042754GO:GO:0043496GO:GO:0043565GO:GO:0045892GO:GO:0045893
GO:GO:0046686GO:GO:0048574hmmpanther:PTHR12802hmmpanther:PTHR12802:SF43HOGENOM:HOG000084594InParanoid:P92973IntAct:P92973
InterPro:IPR001005InterPro:IPR006447InterPro:IPR009057InterPro:IPR017930iPTMnet:P92973KEGG:ath:AT2G46830KO:K12134
OMA:CHEQPSAPaxDb:P92973Pfam:P92973Pfam:PF00249Pfscan:PS51294PhylomeDB:P92973PIR:T02684
PRIDE:P92973PRO:PR:P92973PROSITE:PS51294ProteinModelPortal:P92973Proteomes:UP000006548RefSeq:NP_850460.1RefSeq:NP_850461.1
SMART:SM00717SMR:P92973STRING:3702.AT2G46830.1SUPFAM:SSF46689TAIR:AT2G46830tair10-symbols:CCA1TIGRfam:TIGR01557
TIGRFAMs:TIGR01557UniGene:At.10956UniProt:P92973
Coordinates (TAIR10) chr2:+:19246005..19248717
Molecular Weight (calculated) 66979.10 Da
IEP (calculated) 5.89
GRAVY (calculated) -0.93
Length 608 amino acids
Sequence (TAIR10)
(BLAST)
001: METNSSGEDL VIKTRKPYTI TKQRERWTEE EHNRFIEALR LYGRAWQKIE EHVATKTAVQ IRSHAQKFFS KVEKEAEAKG VAMGQALDIA IPPPRPKRKP
101: NNPYPRKTGS GTILMSKTGV NDGKESLGSE KVSHPEMANE DRQQSKPEEK TLQEDNCSDC FTHQYLSAAS SMNKSCIETS NASTFREFLP SREEGSQNNR
201: VRKESNSDLN AKSLENGNEQ GPQTYPMHIP VLVPLGSSIT SSLSHPPSEP DSHPHTVAGD YQSFPNHIMS TLLQTPALYT AATFASSFWP PDSSGGSPVP
301: GNSPPNLAAM AAATVAAASA WWAANGLLPL CAPLSSGGFT SHPPSTFGPS CDVEYTKAST LQHGSVQSRE QEHSEASKAR SSLDSEDVEN KSKPVCHEQP
401: SATPESDAKG SDGAGDRKQV DRSSCGSNTP SSSDDVEADA SERQEDGTNG EVKETNEDTN KPQTSESNAR RSRISSNITD PWKSVSDEGR IAFQALFSRE
501: VLPQSFTYRE EHREEEQQQQ EQRYPMALDL NFTAQLTPVD DQEEKRNTGF LGIGLDASKL MSRGRTGFKP YKRCSMEAKE SRILNNNPII HVEQKDPKRM
601: RLETQAST
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)