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AT2G46340.1
Subcellular Consensus
(Prediction and Experimental)

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SUBAcon:
nucleus 1.000
What is SUBAcon?
What is ASURE?
SUBAcon computations
Experimental Localisations and PPI
FP MS/MS PPI
SUBAcon links
AGI-AGI relationships
Coexpression PPI
Description (TAIR10) protein_coding : SPA (suppressor of phyA-105) protein family
Curator
Summary (TAIR10)
Encodes a member of the SPA (suppressor of phyA-105) protein family (SPA1-SPA4). SPA proteins contain an N-terminal serine/threonine kinase-like motif followed by a coiled-coil structure and a C-terminal WD-repeat domain. SPA1 is a PHYA signaling intermediate, putative regulator of PHYA signaling pathway. Light responsive repressor of photomorphogenesis. Involved in regulating circadian rhythms and flowering time in plants. Under constant light, the abundance of SPA1 protein exhibited circadian regulation, whereas under constant darkness, SPA1 protein levels remained unchanged. In addition, the spa1-3 mutation slightly shortened circadian period of CCA1, TOC1/PRR1 and SPA1 transcript accumulation under constant light.
Computational
Description (TAIR10)
SUPPRESSOR OF PHYA-105 1 (SPA1); CONTAINS InterPro DOMAIN/s: WD40 repeat 2 (InterPro:IPR019782), WD40 repeat, conserved site (InterPro:IPR019775), WD40 repeat (InterPro:IPR001680), Serine/threonine-protein kinase-like domain (InterPro:IPR017442), Protein kinase-like domain (InterPro:IPR011009), G-protein beta WD-40 repeat, region (InterPro:IPR020472), WD40 repeat-like-containing domain (InterPro:IPR011046), Protein kinase, catalytic domain (InterPro:IPR000719), WD40-repeat-containing domain (InterPro:IPR017986), WD40/YVTN repeat-like-containing domain (InterPro:IPR015943), WD40 repeat, subgroup (InterPro:IPR019781); BEST Arabidopsis thaliana protein match is: SPA1-related 2 (TAIR:AT4G11110.1); Has 31438 Blast hits to 19748 proteins in 684 species: Archae - 32; Bacteria - 4770; Metazoa - 12431; Fungi - 6743; Plants - 3442; Viruses - 2; Other Eukaryotes - 4018 (source: NCBI BLink).
Protein Annotations
BioGrid:4577DIP:DIP-33538NEC:2.7.-.-eggNOG:ENOG410XS0BeggNOG:KOG1033EMBL:AC006526EMBL:AF135455
EMBL:AK221994EMBL:AK227186EMBL:CP002685EnsemblPlants:AT2G46340EnsemblPlants:AT2G46340.1entrez:819242Gene3D:2.130.10.10
GeneID:819242Genevisible:Q9SYX2GO:GO:0004672GO:GO:0005524GO:GO:0005634GO:GO:0009585GO:GO:0009637
GO:GO:0009640GO:GO:0009658GO:GO:0010017GO:GO:0010100GO:GO:0010114GO:GO:0010218GO:GO:0016604
GO:GO:0016607GO:GO:0042802GO:GO:0048575GO:GO:0080008GO:GO:2000028Gramene:AT2G46340.1hmmpanther:PTHR22847
hmmpanther:PTHR22847:SF422HOGENOM:HOG000029775InParanoid:Q9SYX2IntAct:Q9SYX2InterPro:IPR000719InterPro:IPR001680InterPro:IPR011009
InterPro:IPR015943InterPro:IPR017986InterPro:IPR019775InterPro:IPR020472iPTMnet:Q9SYX2KEGG:ath:AT2G46340KO:K16240
MINT:MINT-276478ncoils:CoilOMA:EDAYFFMPaxDb:Q9SYX2Pfam:PF00069Pfam:PF00400Pfam:Q9SYX2
Pfscan:PS50011Pfscan:PS50082Pfscan:PS50294PhylomeDB:Q9SYX2PIR:F84901PIR:G84901PRIDE:Q9SYX2
PRINTS:PR00320PRO:PR:Q9SYX2PROSITE:PS00678PROSITE:PS50011PROSITE:PS50082PROSITE:PS50294ProteinModelPortal:Q9SYX2
Proteomes:UP000006548Reactome:R-ATH-349425RefSeq:NP_182157.2scanprosite:PS00678SMART:SM00320SMR:Q9SYX2STRING:3702.AT2G46340.1
SUPFAM:SSF50978SUPFAM:SSF56112TAIR:AT2G46340tair10-symbols:SPA1UniGene:At.11156UniProt:Q9SYX2
Coordinates (TAIR10) chr2:-:19022572..19026821
Molecular Weight (calculated) 114692.00 Da
IEP (calculated) 7.36
GRAVY (calculated) -0.52
Length 1029 amino acids
Sequence (TAIR10)
(BLAST)
0001: MPVMERVAEE TVATNNIQLK ARVDDVPCNK LDARHNDMVI QSETANSDCP GSSAHRNVDL TKPPPPEEAA GAKLSVEELT LGNYRIVQGS NNTNVDSPRA
0101: GKFEHLYRLA RGSAFRAGDG DLDSQPRDMD QMLSRIRQQL AGAPSERQNL KPFMSRRSDQ NLEAFSERLR AAGENSIMNA PALISEGVQM KTPVSSSNFS
0201: QLLLKRAMKG KGVVGKNQET PPEFVSDQDL GSKEKKLDIS KSPTPHDVLP LKSSPKGNGM VSHGDGNHSK SSIGISLREF LRSSYAKREK RHGLCLFRQL
0301: VELVDSAHSK RLFLLDLRPS LFTLVPSKKL RYIGNFGKND LESDVDEDLN RRRPVVEESS SGGRDSKKRK MDLHLNSPGN QLQATSTGRP FKRKSPVIDL
0401: NMVDARNPDS CELQQQDYIK NLSVSSVSRK QSMSTWLEEQ WYTCPEEING EDIGEKSNIY ALGVLLFELL CHCESGEMHA AMMADLRHRI LPPTFLSKYP
0501: KEAGFCLWLL HPEPSSRPSA RDILKSELIC EDDSVKSTAA AEEISELLLH FLSSLEVQKK KKASKLLQDI QTLEDDIKEA ERRYSSNVSL VRSHGAIEKR
0601: VQSSPLDEHC TTSSALFVPT ANTDRLMSNI RQLEDAYFFM RSQINLSSSA ATARSDKTLK DRDRCSENQN ENQDMSTKGK SSDQLEVFFE GLCKFARYSK
0701: FETCGTIRSG DLLNSASVVC SLSFDPDEEH IAAAGISKKI KIFDFNAFMN ESVGVHYPLV EMVNKSKLSC VCWNSYIKNY LASTDYDGVV QIWDAGTGQG
0801: FSQYTEHQKR AWSVDFSPSD PTKFVSGSDD CSVKLWSINE KRSLGTIWSP ANVCCVQFSS YSNHLLAFGS ADYKVYCYDL RYVKTPWCTL AGHEKAVSYV
0901: KFMDSETIVS ASTDNSLKLW NLNKTNSSGL SPGACSLTYK GHTNQKNFVG LSVLDGYIAC GSETNEVYSY YKSLPMPMTS YKFGSVDPIS GNEYFDDNGQ
1001: FVSSVCWRKK SNMLVAANST GNMKLLKLV
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)