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AT2G44180.1
Subcellular Consensus
(Prediction and Experimental)

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SUBAcon:
cytosol 0.989
What is SUBAcon?
What is ASURE?
SUBAcon computations
Experimental Localisations and PPI
FP MS/MS PPI
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no PPI data
Description (TAIR10) protein_coding : methionine aminopeptidase 2A
Curator
Summary (TAIR10)
Encodes a MAP2 like methionine aminopeptidase. In MAP1A mutant background plants show an increased sensitivity to fumagillin resulting in defects in development. Phenotype is similar to RNAi lines which knock out all MAP2/MAP1 loci.
Computational
Description (TAIR10)
methionine aminopeptidase 2A (MAP2A); FUNCTIONS IN: metalloexopeptidase activity, aminopeptidase activity; INVOLVED IN: N-terminal protein amino acid modification; LOCATED IN: cytoplasm; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Peptidase M24, structural domain (InterPro:IPR000994), Peptidase M24A, methionine aminopeptidase, subfamily 2 (InterPro:IPR002468), Peptidase M24A, methionine aminopeptidase, subfamily 2, binding site (InterPro:IPR018349), Peptidase M24, methionine aminopeptidase (InterPro:IPR001714); BEST Arabidopsis thaliana protein match is: methionine aminopeptidase 2B (TAIR:AT3G59990.4); Has 6503 Blast hits to 6494 proteins in 2220 species: Archae - 231; Bacteria - 4255; Metazoa - 425; Fungi - 336; Plants - 181; Viruses - 0; Other Eukaryotes - 1075 (source: NCBI BLink).
Protein Annotations
EC:3.4.11.18eggNOG:COG0024eggNOG:KOG2775EMBL:AK228284EnsemblPlants:AT2G44180EnsemblPlants:AT2G44180.1entrez:819025
ExpressionAtlas:Q0WRL9Gene3D:1.10.10.10Gene3D:3.90.230.10GeneID:819025GO:GO:0005737GO:GO:0046872GO:GO:0070006
GO:GO:0070084Gramene:AT2G44180.1HAMAP:MF_03175hmmpanther:PTHR10804hmmpanther:PTHR10804:SF9InterPro:IPR000994InterPro:IPR001714
InterPro:IPR002468InterPro:IPR011991InterPro:IPR018349KEGG:ath:AT2G44180KO:K01265merops:M24.A02ncoils:Coil
OMA:LMIDICEPANTHER:PTHR10804:SF9PaxDb:Q0WRL9Pfam:PF00557Pfam:Q9FV49PhylomeDB:Q0WRL9PRIDE:Q0WRL9
PRINTS:PR00599PROSITE:PS01202ProteinModelPortal:Q0WRL9Proteomes:UP000006548RefSeq:NP_566013.1scanprosite:PS01202SMR:Q0WRL9
STRING:3702.AT2G44180.1SUPFAM:SSF46785SUPFAM:SSF55920TAIR:AT2G44180tair10-symbols:MAP2ATIGRfam:TIGR00501TIGRFAMs:TIGR00501
UniGene:At.19509UniProt:Q0WRL9UniProt:Q9FV49
Coordinates (TAIR10) chr2:-:18269442..18271785
Molecular Weight (calculated) 49397.60 Da
IEP (calculated) 5.72
GRAVY (calculated) -0.60
Length 441 amino acids
Sequence (TAIR10)
(BLAST)
001: MAIGNPEVAT MGKENTEAES SNGNESQLSS DLTKSLDLAE VKEDEKDNNQ EEEDGLKAEA STKKKKKKSK SKKKKSSLQQ TDPPSIPVLE LFPSGDFPQG
101: EIQQYNDDNL WRTTSEEKRE MERLQKPIYN SLRQAAEVHR QVRKYMRSIL KPGMLMIDLC ETLENTVRKL ISENGLQAGI AFPTGCSLNN VAAHWTPNSG
201: DKTVLQYDDV MKLDFGTHID GHIVDSAFTV AFNPMFDPLL AASRDATYTG IKEAGVDVRL CDVGAAVQEV MESYEVEING KVYQVKSIRN LNGHSIGRYQ
301: IHAEKSVPNV RGGEQTKMEE GELYAIETFG STGKGYVRED LECSHYMKNY DVGHVPLRLP RAKQLLATIN KNFSTLAFCR RYLDRLGETK YLMALKNLCD
401: SGIIEPCPPV CDVKGSYISQ FEHTILLRPT CKEIISKGDD Y
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)