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AT2G42890.1
Subcellular Consensus
(Prediction and Experimental)

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SUBAcon:
nucleus 0.999
What is SUBAcon?
What is ASURE?
SUBAcon computations
Experimental Localisations and PPI
FP MS/MS PPI
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no PPI data
Description (TAIR10) protein_coding : MEI2-like 2
Curator
Summary (TAIR10)
A member of mei2-like gene family, predominantly plant-based family of genes encoding RNA binding proteins with characteristic presence of a highly conserved RNA binding motif first described in the mei2 gene of the fission yeast S. pombe. In silico analyses reveal nine mei2 -like genes in A. thaliana. They were grouped into four distinct clades, based on overall sequence similarity and subfamily-specific sequence elements. AML2 is a member of two sister clades of mei2-like gene family, AML1 through AML5, and belongs to the clade named ALM235. AML2 is expressed during early embryo development (heart and torpedo stage) and predominantly in vegetative organs; no significant accumulation was detected in floral apices.
Computational
Description (TAIR10)
MEI2-like 2 (ML2); FUNCTIONS IN: RNA binding, nucleotide binding, nucleic acid binding; LOCATED IN: chloroplast; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: RNA recognition motif, RNP-1 (InterPro:IPR000504), RNA recognition motif 2 (InterPro:IPR007201), Nucleotide-binding, alpha-beta plait (InterPro:IPR012677); BEST Arabidopsis thaliana protein match is: MEI2-like protein 5 (TAIR:AT1G29400.2); Has 7613 Blast hits to 6033 proteins in 353 species: Archae - 6; Bacteria - 46; Metazoa - 4198; Fungi - 1128; Plants - 1433; Viruses - 0; Other Eukaryotes - 802 (source: NCBI BLink).
Protein Annotations
eggNOG:ENOG4111R9FeggNOG:KOG4660EMBL:AC006580EMBL:AC006931EMBL:AF101056EMBL:AF367316EMBL:AY143940
EMBL:CP002685EnsemblPlants:AT2G42890EnsemblPlants:AT2G42890.1entrez:818890ExpressionAtlas:Q9SJG8Gene3D:3.30.70.330GeneID:818890
Genevisible:Q9SJG8GO:GO:0000166GO:GO:0003723GO:GO:0045836GO:GO:0045927GO:GO:0051321hmmpanther:PTHR24012
hmmpanther:PTHR24012:SF390HOGENOM:HOG000030212InParanoid:Q9SJG8InterPro:IPR000504InterPro:IPR007201InterPro:IPR012677iPTMnet:Q9SJG8
OMA:PTLFHEKPaxDb:Q9SJG8Pfam:PF00076Pfam:PF04059Pfam:Q9SJG8Pfscan:PS50102PhylomeDB:Q9SJG8
PIR:E84859PRIDE:Q9SJG8PRO:PR:Q9SJG8PROSITE:PS50102ProteinModelPortal:Q9SJG8Proteomes:UP000006548RefSeq:NP_565990.1
SMART:SM00360SMR:Q9SJG8STRING:3702.AT2G42890.1SUPFAM:SSF54928TAIR:AT2G42890tair10-symbols:AML2tair10-symbols:ML2
UniGene:At.25505UniProt:Q9SJG8
Coordinates (TAIR10) chr2:+:17850077..17854205
Molecular Weight (calculated) 93219.70 Da
IEP (calculated) 5.67
GRAVY (calculated) -0.56
Length 843 amino acids
Sequence (TAIR10)
(BLAST)
001: MVSSIIAVAE GKKMELEPNK SLSADMPSLL SRSSEAFNGG TGYRSSSDLS MFSSSLPTLF HEKLNMTDSD SWLSFDESSP NLNKLVIGNS EKDSLEDVEP
101: DALEILLPED ENELLPGLID ELNFTGLPDE LDDLEECDVF CTGGGMELDV ESQDNHAVDA SGMQISDRGA ANAFVPRKRP NTAGRVSVEH PNGEHPSRTL
201: FVRNINSSVE DSELSALFEP FGEIRSLYTA CKSRGFVMIS YYDIRAAHAA MRALQNTLLR KRTLDIHFSI PKENPSEKDM NQGTLVIFNV DTTVSNDELL
301: QLFGAYGEIR EIRETPNRRF HRFIEYYDVR DAETALKALN RSEIGGKCIK LELSRPGGAR RLSVPSQSQD LERTEVTNFY NQVGSHVANS PPGNWPIGSP
401: VKGSPSHAFT RPHGLGMVRP VNSDNMPGLA SILPAHPSSF HGFSPVSNDQ GLLNHSNQTI LNKGLMHNIS YGQPHSLPEH ITGGISNSMR FIAPHSSGFG
501: TSSDHRYRWG SPPQHMNYPG YTGVSSSSSS TERPFTVRHG FPFAERQASL LGKYQHHVGS APSSIHFNTQ MNCYTGSPEI PLGFSDMGIN RNYNSAHGKA
601: NLGVSLPGNS SEQDFTGFGM SSMPTVPFGG SRGLQSVRPE PFAEQGRIHN HESHNQNQFI DGGRYHIDLD RIASGDEIRT TLIIKNIPNK YTYKMLVAEI
701: DEKHKGDYDF LCLPTDFKNK CNMGHAFINM VSPLHIVPFQ QTFNGKIWEK FNSGKVASLA YAEIQGKSAL ASYMQTPSSM KEQKQLFPEV SYHDDGQDAN
801: DHEQLFSSIW NITAPDSDWS YTMDLIENPR ENGNSKNAAE ESS
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)