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AT2G42580.1
Subcellular Consensus
(Prediction and Experimental)

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SUBAcon:
nucleus 0.967
What is SUBAcon?
What is ASURE?
SUBAcon computations
Experimental Localisations and PPI
FP MS/MS PPI
  • PMID:24134884 (2013): cytoskeleton microtubules
SUBAcon links
AGI-AGI relationships
Coexpression PPI
Description (TAIR10) protein_coding : tetratricopetide-repeat thioredoxin-like 3
Curator
Summary (TAIR10)
Encodes a member of the TTL family and contains a thioredoxin like domain and three tandom TPRs. Interacts physically with BRL2/VH1 and appears to play a role in brassiosteroid and auxin signaling.
Computational
Description (TAIR10)
tetratricopetide-repeat thioredoxin-like 3 (TTL3); FUNCTIONS IN: binding; INVOLVED IN: brassinosteroid mediated signaling pathway, auxin mediated signaling pathway, leaf vascular tissue pattern formation; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Molecular chaperone, heat shock protein, Hsp40, DnaJ (InterPro:IPR015609), Tetratricopeptide TPR-1 (InterPro:IPR001440), Thioredoxin fold (InterPro:IPR012335), Tetratricopeptide-like helical (InterPro:IPR011990), Thioredoxin domain (InterPro:IPR013766), Tetratricopeptide repeat-containing (InterPro:IPR013026), Thioredoxin-like fold (InterPro:IPR012336), Tetratricopeptide repeat (InterPro:IPR019734); BEST Arabidopsis thaliana protein match is: tetratricopetide-repeat thioredoxin-like 4 (TAIR:AT3G58620.1); Has 21212 Blast hits to 11305 proteins in 1032 species: Archae - 491; Bacteria - 3820; Metazoa - 5890; Fungi - 2224; Plants - 2157; Viruses - 6; Other Eukaryotes - 6624 (source: NCBI BLink).
Protein Annotations
BioGrid:4195eggNOG:COG0457eggNOG:KOG0907eggNOG:KOG1124EMBL:AC007087EMBL:AF367321EMBL:AY143941
EMBL:CP002685EnsemblPlants:AT2G42580EnsemblPlants:AT2G42580.1entrez:818858Gene3D:1.25.40.10Gene3D:3.40.30.10GeneID:818858
Genevisible:Q9SIN1GO:GO:0005623GO:GO:0006970GO:GO:0009734GO:GO:0009742GO:GO:0010305GO:GO:0045454
Gramene:AT2G42580.1hmmpanther:PTHR22904hmmpanther:PTHR22904:SF297HOGENOM:HOG000237654InParanoid:Q9SIN1IntAct:Q9SIN1InterPro:IPR011990
InterPro:IPR012336InterPro:IPR013026InterPro:IPR013766InterPro:IPR019734iPTMnet:Q9SIN1KEGG:ath:AT2G42580OMA:SIKHFLL
PaxDb:Q9SIN1Pfam:PF00085Pfam:PF00515Pfam:PF13414Pfam:Q9SIN1Pfscan:PS50005Pfscan:PS50293
PhylomeDB:Q9SIN1PIR:F84855PRIDE:Q9SIN1PRO:PR:Q9SIN1PROSITE:PS50005PROSITE:PS50293ProteinModelPortal:Q9SIN1
Proteomes:UP000006548RefSeq:NP_565976.1SMART:SM00028SMR:Q9SIN1STRING:3702.AT2G42580.1SUPFAM:SSF48452SUPFAM:SSF52833
TAIR:AT2G42580tair10-symbols:TTL3tair10-symbols:VITUniGene:At.14365UniProt:Q9SIN1
Coordinates (TAIR10) chr2:+:17728855..17731461
Molecular Weight (calculated) 75465.40 Da
IEP (calculated) 8.96
GRAVY (calculated) -0.42
Length 691 amino acids
Sequence (TAIR10)
(BLAST)
001: MSHSRRLSLE PAIDSITGRF RDLQRNDDDV NKPDFRELDL GSPVSTLMPR GSASSSAAAT PTSSSGSSGS ASGKPSVSSQ MAKRLDDAYK SHSGELSSPG
101: SGMPTTTRIL KPGHRRSSST GTPLIFSGSS FTSATSHTSP QGGGSGATSA VSPNTGVLPA GNICPSGRIL KTGMASRTSS RTETLCTGTG NYGHGNVVRS
201: GGGGGTSGKA VRVAENGENP EELKRMGNDM YRRGSFSEAL SLYDRAILIS PGNAAYRSNR AAALTALRRL GEAVKECLEA VRIDPSYSRA HQRLASLYLR
301: LGEAENARRH ICFSGQCPDQ ADLQRLQTLE KHLRRCWEAR KIGDWKTAIK ETDAAIANGA DSSPQLVACK AEAFLRLKQI EDSDFCVSCI PRLDHHYHSQ
401: PQVKLFGMVV EAYVLCIQAQ VDMALGRFEN AVVKAERAAM LDQTNPEVVS VLNNVKMVVR ARTRGNELFS SGRFSEACVA YGDGLKQDDS NSVLYCNRAA
501: CWYKLGLWEK SVEDCNHALK SQPSYIKALL RRAASYGKLG RWEDAVKDYE FLRRELPGDS EVAESLERAK TVLMNRSQES KSLGFNNEVE AVSTLDKFKK
601: SVALPGVSVF HFKSSSNRQC EEISPFINTL CLRYPLVHFF MVDVEESMAL AKAESIRKVP TFKMYKNGDK VKEMVCPSHQ FLEDSIKHFL L
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)