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AT2G41540.1
Subcellular Consensus
(Prediction and Experimental)

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SUBAcon:
cytosol 0.722
What is SUBAcon?
What is ASURE?
SUBAcon computations
Experimental Localisations and PPI
FP MS/MS PPI
  • PMID:25900983 (2015): Golgi trans-Golgi network
  • PMID:25900983 (2015): Golgi trans-Golgi network multivesicular body
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no PPI data
Description (TAIR10) protein_coding : 6-phosphogluconate dehydrogenase family protein
Curator
Summary (TAIR10)
Encodes a protein with NAD-dependent glycerol-3-phosphate (G3P) dehydrogenase which was shown to complement an Escherichia coli strain: BB20-14, auxotrophic for glycerol/G3P due to a loss-of-function mutation in the gpsA gene.
Computational
Description (TAIR10)
GPDHC1; CONTAINS InterPro DOMAIN/s: 6-phosphogluconate dehydrogenase, C-terminal-like (InterPro:IPR008927), Dehydrogenase, multihelical (InterPro:IPR013328), NAD(P)-binding domain (InterPro:IPR016040), NAD-dependent glycerol-3-phosphate dehydrogenase, C-terminal (InterPro:IPR006109), NAD-dependent glycerol-3-phosphate dehydrogenase, N-terminal (InterPro:IPR011128), NAD-dependent glycerol-3-phosphate dehydrogenase (InterPro:IPR006168); BEST Arabidopsis thaliana protein match is: 6-phosphogluconate dehydrogenase family protein (TAIR:AT3G07690.1); Has 4956 Blast hits to 4956 proteins in 1719 species: Archae - 20; Bacteria - 3172; Metazoa - 444; Fungi - 126; Plants - 154; Viruses - 0; Other Eukaryotes - 1040 (source: NCBI BLink).
Protein Annotations
BioCyc:ARA:AT2G41540-MONOMERBioCyc:ARA:GQT-489-MONOMERBioCyc:ARA:GQT-490-MONOMERBioGrid:4089BRENDA:1.1.1.8EC:1.1.1.8eggNOG:COG0240
eggNOG:KOG2711EMBL:AC002510EMBL:AJ347019EMBL:AK317356EMBL:AY063920EMBL:AY091247EMBL:CP002685
EnsemblPlants:AT2G41540EnsemblPlants:AT2G41540.1EnsemblPlants:AT2G41540.2EnsemblPlants:AT2G41540.3entrez:818752Gene3D:1.10.1040.10Gene3D:3.40.50.720
GeneID:818752Genevisible:O22216GO:GO:0004367GO:GO:0005829GO:GO:0005975GO:GO:0009331GO:GO:0046168
GO:GO:0051287Gramene:AT2G41540.1Gramene:AT2G41540.2Gramene:AT2G41540.3gramene_pathway:1.1.1.8gramene_pathway:PWY-6118hmmpanther:PTHR11728
hmmpanther:PTHR11728:SF17HOGENOM:HOG000238366InParanoid:O22216InterPro:IPR006109InterPro:IPR006168InterPro:IPR008927InterPro:IPR011128
InterPro:IPR013328InterPro:IPR016040KEGG:00564+1.1.1.94KEGG:ath:AT2G41540KO:K00006OMA:THAFFELPaxDb:O22216
Pfam:O22216Pfam:PF01210Pfam:PF07479PhylomeDB:O22216PIR:T00810PRIDE:O22216PRINTS:PR00077
PRO:PR:O22216ProteinModelPortal:O22216Proteomes:UP000006548RefSeq:NP_001031525.1RefSeq:NP_181685.1RefSeq:NP_850352.1SMR:O22216
STRING:3702.AT2G41540.1SUPFAM:SSF48179SUPFAM:SSF51735TAIR:AT2G41540tair10-symbols:GPDHC1UniGene:At.21264UniGene:At.69847
unipathway:UPA00940UniProt:O22216
Coordinates (TAIR10) chr2:+:17326801..17328654
Molecular Weight (calculated) 51494.30 Da
IEP (calculated) 7.29
GRAVY (calculated) -0.11
Length 462 amino acids
Sequence (TAIR10)
(BLAST)
001: MVGSIEAKSL QSNGSVHHIG LNLEEKLDEF RRLLGKSEKD PLRIVSVGAG AWGSVFAALL QESYGGFRDK FQIRIWRRAG RAVDRETAEH LFEVINSRED
101: ILRRLIRRCA YLKYVEARLG DRTLYADEIL KDGFCLNMVD TPLCPLKVVT NLQEAVWDAD IVVNGLPSTE TREVFEEISK YWKERITVPI IISLSKGIET
201: ALEPVPHIIT PTKMIHQATG VPIDNVLYLG GPNIAAEIYN KEYANARICG AAKWRKPLAK FLRQPHFIVW DNSDLVTHEV MGGLKNVYAI GAGMVAALTN
301: ESATSKSVYF AHCTSEMIFI THLLAEEPEK LAGPLLADTY VTLLKGRNAW YGQMLAKGEI NRDMGDSISG KGMIQGVSAV GAFYQLLSQS SLSILPSEEK
401: KPVAPVESCP ILKTLYKILI TREQSTQAIL QALRDETLND PRDRIEIAQS HAFYRPSLLG QP
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)