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AT2G38440.1
Subcellular Consensus
(Prediction and Experimental)

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SUBAcon:
cytosol 0.954
What is SUBAcon?
What is ASURE?
SUBAcon computations
Experimental Localisations and PPI
FP MS/MS PPI
  • PMID:25402197 (2015): plastid plastid thylakoid plastid thylakoid membrane
  • PMID:17317660 (2007): plasma membrane
SUBAcon links
AGI-AGI relationships
Coexpression PPI
Description (TAIR10) protein_coding : SCAR homolog 2
Curator
Summary (TAIR10)
Encodes a subunit of the WAVE complex. The WAVE complex is required for activation of ARP2/3 complex which functions in actin microfilament nucleation and branching. Mutations cause defects in both the actin and microtubule cytoskeletons that result in aberrant epidermal cell expansion. itb1 mutants showed irregularities in trichome branch positioning and expansion. The SHD domain of this protein binds to BRK1 and overexpression of the SHD domain results in a dominant negative phenotype.
Computational
Description (TAIR10)
SCAR homolog 2 (SCAR2); FUNCTIONS IN: molecular_function unknown; INVOLVED IN: in 6 processes; LOCATED IN: SCAR complex, plasma membrane, cytoplasm; EXPRESSED IN: 26 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Actin-binding WH2 (InterPro:IPR003124); BEST Arabidopsis thaliana protein match is: SCAR family protein 4 (TAIR:AT5G01730.1); Has 5162 Blast hits to 2275 proteins in 363 species: Archae - 24; Bacteria - 2785; Metazoa - 880; Fungi - 591; Plants - 224; Viruses - 0; Other Eukaryotes - 658 (source: NCBI BLink).
Protein Annotations
BioGrid:3767eggNOG:ENOG410IJAEeggNOG:ENOG4111H25EMBL:AC004683EMBL:AY743924EMBL:AY817016EMBL:CP002685
EnsemblPlants:AT2G38440EnsemblPlants:AT2G38440.1entrez:818425GeneID:818425Genevisible:Q5XPJ9GO:GO:0005737GO:GO:0005856
GO:GO:0005886GO:GO:0010090GO:GO:0010091GO:GO:0016337GO:GO:0030036GO:GO:0031209GO:GO:0045010
GO:GO:0051127Gramene:AT2G38440.1hmmpanther:PTHR12902hmmpanther:PTHR12902:SF12HOGENOM:HOG000154261InParanoid:Q5XPJ9IntAct:Q5XPJ9
InterPro:IPR003124InterPro:IPR028288iPTMnet:Q5XPJ9KEGG:ath:AT2G38440OMA:DAPQTHGPANTHER:PTHR12902PaxDb:Q5XPJ9
Pfam:Q5XPJ9Pfscan:PS51082PhylomeDB:Q5XPJ9PIR:T02501PRIDE:Q5XPJ9PRO:PR:Q5XPJ9PROSITE:PS51082
ProteinModelPortal:Q5XPJ9Proteomes:UP000006548RefSeq:NP_181378.2STRING:3702.AT2G38440.1TAIR:AT2G38440tair10-symbols:ATSCAR2tair10-symbols:DIS3
tair10-symbols:ITB1tair10-symbols:SCAR2tair10-symbols:WAVE4UniGene:At.12785UniProt:Q5XPJ9
Coordinates (TAIR10) chr2:+:16095550..16100851
Molecular Weight (calculated) 151592.00 Da
IEP (calculated) 4.23
GRAVY (calculated) -0.62
Length 1399 amino acids
Sequence (TAIR10)
(BLAST)
0001: MPLTRYQSRN EYGLADPDLY QAADKDDPEA LLEGVAMAGL VGILRQLGDL AEFAAEMFHD LHEEVMATAS RSHGLMARVQ QLEAEFPSIE KALLCQTDHS
0101: PFFSNKGVEW HPNLQLEQSV VTSGDLPRCV MDSYEECRGP PRLFLLDKFD ISGAGACLKR YTDPSFVRLE TSSYEESWDD IQREKKSQKA KRRASQWRNG
0201: GTPENALSSH AKLHELFLEE HLEAHHSDPA RVVKLKTRKL DGCSLISKSG ESYMEKFVQT RVDSKISYEI ITQNPGLLTW NMDSARDVVT DIPEISMVGA
0301: MDKSHGGSRA EVSFPSEQEN VANVNMNGGF IEKDIETVPE STYNEVRGTT ITQDSQTVLN GKPGFFQQRS YSEDLTSEAD NYVDAPATME SETETDDECR
0401: PKSRSDTLKD GNHHIYSDAV EERMEDPPQF SFSHSNGNTP VSENGRSSFG KKSTSYSYSD TASISIDDQS DGEKLSGCLP STSSFKSELV DSMSHVTPEA
0501: NKVSHDLNVQ ESVSSSNVDG QTSLSSNGTC SSPRPVSQND QSCSLTVQSL ASEVVETSPE LVRLDLMKGG NDGRKVDPFD SSKSCASFDA KNSDLPSETS
0601: SISSTSEGSR CDSTIEKNCM VASNLVNSGT SPQAFVDSQT GKQLPIADTD FETNSIVACS EVLANSGSDP EERDGRCLTG KLVPCSAGVG MEVSPDTPSK
0701: VCGPSSADGI HLKDTLDDET DCVSVTNVVV DVDSKNSVAD VGSQSSVADI DSQSSVAEIS DEHSCAFGNT ADVSVSESHE DTLENGMSVP SDFNSGVEKL
0801: AGDASPTCSK CDDHISHEGF HDLSGLDNAT TDIVPNVELD VSDNDNDTSS GGVNHAVSLS STRGKGSLPW ISTNTYQSSS DAGEIFHDTV VESDGTLLED
0901: NNPESEIKMH KSPLEVSSEG LSTEPDNKDV ESIESTSPKP SLDQRNRDTE TKSPGESILD DNCIDSTQVY NLNLLESEAI DQAVREQTSY ASHEVADEEL
1001: LQSNVFRGLE FEPQSAGLEF APQSAGIELN RPKQELNLDP TFPSFGFIPE TIPPNPEDMP PLPPMQWLIG KVPHSFPTFM GESVETSSSA LSAAPPIGSS
1101: LNVQIGSPPS ELSVSLGSDE SERLPGGFVH NASEKPLQSS IQFPTMSTDL NSQYDSSELP TIPYQECIED FGSEENNLLA DHAAQNHELV YSQASSLQLP
1201: QVKHEDFKDD ADVHESQSSS DDHHCPETKS LTPTQSTKVE DKGHSVPDAS NAETAESSNT SVQKINPVSV GDAMWPVSCF SVAPTLDTYK TEVVPTVRLP
1301: RPRSPLVDAV AAHDRRKMKK VSEMVHPPIK SKQDDKDSLL AQIRNKSVNL KPAVTTRPSI QTGPRTDLRV AAILEKANTI RMAMAGSDED EDSDSWSDS
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)