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AT2G37410.1
Subcellular Consensus
(Prediction and Experimental)

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SUBAcon:
mitochondrion 1.000
ASURE: mitochondrion
What is SUBAcon?
What is ASURE?
SUBAcon computations
Experimental Localisations and PPI
FP MS/MS PPI
  • PMID:27943495 (2017): mitochondrion
  • PMID:25900983 (2015): Golgi trans-Golgi network
  • PMID:25900983 (2015): Golgi trans-Golgi network early endosome
  • PMID:25900983 (2015): Golgi trans-Golgi network multivesicular body
  • PMID:22923678 (2012): mitochondrion
  • PMID:21841088 (2011): mitochondrion
  • PMID:19334764 (2009): plasma membrane
  • PMID:15276431 (2004): mitochondrion
  • PMID:14730085 (2004): mitochondrion
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no PPI data
Description (TAIR10) protein_coding : translocase inner membrane subunit 17-2
Curator
Summary (TAIR10)
Mitochondrial inner membrane translocase. Together with AtTIM17-1, TIM17-2 has a long C-terminal extension not present in other TIMs. The extension is located in the outer membrane and so TIM17-2 links the inner and outer mitochondrial membranes. The C-terminal region is essential for protein import into mitochondria via the general import pathway but is not necessary for import via the carrier pathway.
Computational
Description (TAIR10)
translocase inner membrane subunit 17-2 (TIM17-2); FUNCTIONS IN: protein transporter activity, P-P-bond-hydrolysis-driven protein transmembrane transporter activity; INVOLVED IN: protein transport, protein import into mitochondrial inner membrane; LOCATED IN: mitochondrial outer membrane, mitochondrion, mitochondrial inner membrane, mitochondrial inner membrane presequence translocase complex; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Mitochondrial inner membrane translocase complex, subunit Tim17/22 (InterPro:IPR003397); BEST Arabidopsis thaliana protein match is: translocase inner membrane subunit 17-1 (TAIR:AT1G20350.1); Has 2051 Blast hits to 1654 proteins in 249 species: Archae - 0; Bacteria - 134; Metazoa - 977; Fungi - 256; Plants - 141; Viruses - 2; Other Eukaryotes - 541 (source: NCBI BLink).
Protein Annotations
BioGrid:3661eggNOG:COG5596eggNOG:KOG1652EMBL:AC005896EMBL:AF186847EMBL:AF360258EMBL:AY040072
EMBL:AY056107EMBL:CP002685EnsemblPlants:AT2G37410EnsemblPlants:AT2G37410.1EnsemblPlants:AT2G37410.2entrez:818317GeneID:818317
Genevisible:Q9SP35GO:GO:0005739GO:GO:0005741GO:GO:0005743GO:GO:0005744GO:GO:0015450GO:GO:0030150
GO:GO:0031305Gramene:AT2G37410.1Gramene:AT2G37410.2hmmpanther:PTHR10485hmmpanther:PTHR10485:SF0HOGENOM:HOG000183190InParanoid:Q9SP35
InterPro:IPR003397InterPro:IPR005678KEGG:ath:AT2G37410KO:K17795OMA:MMTESSAPANTHER:PTHR10485PaxDb:Q9SP35
Pfam:PF02466Pfam:Q9SP35PhylomeDB:Q9SP35PIR:D84792PRIDE:Q9SP35PRO:PR:Q9SP35ProteinModelPortal:Q9SP35
Proteomes:UP000006548RefSeq:NP_181277.1RefSeq:NP_973621.1STRING:3702.AT2G37410.1TAIR:AT2G37410tair10-symbols:ATTIM17-2tair10-symbols:TIM17
tair10-symbols:TIM17-2UniGene:At.11720UniProt:Q9SP35
Coordinates (TAIR10) chr2:-:15698119..15698850
Molecular Weight (calculated) 25572.70 Da
IEP (calculated) 4.99
GRAVY (calculated) -0.27
Length 243 amino acids
Sequence (TAIR10)
(BLAST)
001: MGTPETSREP CPDRILDDIG GAFGMGAVGG SAFHFIKGTY NSPKGSRFVG GTQSVSMNAP RTGGSFAVWG GLFSTFDCTM VYLRQKEDPW NSIIAGAATG
101: GFLSMRQGAG AASRSAIFGG VLLALIEGAG IMLNKVLAQP QNMMMEDPGM QGMPGMQGMQ GMPGMPGMQG MPGMQGMQMG QMQSQAQIRS ESQNQNTASS
201: SSSSSWFGGL FDKKKEEVQP GSESKTEVLE SFDAPPVPSF EFK
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)