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AT2G35110.1
Subcellular Consensus
(Prediction and Experimental)

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SUBAcon:
endoplasmic reticulum 1.000
What is SUBAcon?
What is ASURE?
SUBAcon computations
Experimental Localisations and PPI
FP MS/MS PPI
  • PMID:27451899 (2016): endoplasmic reticulum endoplasmic reticulum membrane
  • PMID:27451899 (2016): endoplasmic reticulum actin filament
  • PMID:27451899 (2016): endoplasmic reticulum microtubules
  • PMID:26781341 (2016): plasma membrane
  • PMID:24134884 (2013): cytoskeleton microtubules
  • PMID:19334764 (2009): plasma membrane
SUBAcon links
AGI-AGI relationships
Coexpression PPI
Description (TAIR10) protein_coding : transcription activators
Curator
Summary (TAIR10)
Component of the WAVE protein complex which act as activators of ARP2/3 complex involved in actin nucleation. Required for trichome morphogenesis. Mutant displays distorted trichomes, a phenotype that can be phenocopied by treatment of WT plants with actin-interacting drugs.
Computational
Description (TAIR10)
GNARLED (GRL); CONTAINS InterPro DOMAIN/s: Nck-associated protein 1 (InterPro:IPR019137); Has 2387 Blast hits to 741 proteins in 151 species: Archae - 0; Bacteria - 54; Metazoa - 569; Fungi - 142; Plants - 67; Viruses - 0; Other Eukaryotes - 1555 (source: NCBI BLink).
Protein Annotations
BioGrid:3423DIP:DIP-29825NeggNOG:ENOG410XPQIeggNOG:KOG1917EMBL:AC004667EMBL:AY496700EMBL:AY662956
EMBL:AY787211EMBL:BK004072EMBL:CP002685EnsemblPlants:AT2G35110EnsemblPlants:AT2G35110.1entrez:818077ExpressionAtlas:Q5S2C4
GeneID:818077Genevisible:Q5S2C4GO:GO:0005634GO:GO:0005789GO:GO:0007015GO:GO:0009825GO:GO:0010090
GO:GO:0031209GO:GO:0045010GO:GO:0045893hmmpanther:PTHR12093hmmpanther:PTHR12093:SF10HOGENOM:HOG000029915InParanoid:Q5S2C4
IntAct:Q5S2C4InterPro:IPR019137iPTMnet:Q5S2C4KEGG:ath:AT2G35110ncoils:CoilOMA:MTSNIWNPaxDb:Q5S2C4
Pfam:PF09735Pfam:Q5S2C4PhylomeDB:Q5S2C4PIR:G84764PRIDE:Q5S2C4PRO:PR:Q5S2C4ProteinModelPortal:Q5S2C4
Proteomes:UP000006548RefSeq:NP_001031485.1RefSeq:NP_181056.2SMR:Q5S2C4STRING:3702.AT2G35110.1TAIR:AT2G35110tair10-symbols:GRL
tair10-symbols:NAP1tair10-symbols:NAPPUniGene:At.22860UniProt:Q5S2C4
Coordinates (TAIR10) chr2:-:14795970..14803525
Molecular Weight (calculated) 158924.00 Da
IEP (calculated) 6.53
GRAVY (calculated) -0.17
Length 1425 amino acids
Sequence (TAIR10)
(BLAST)
0001: MANSRQYYPS QDESMSPTSV RSREWEGPSR WTEYLGPEMA ASVSSTRSSK QIDGHVGGST KALNIQWVVQ MIEVADGLMA KMYRLNQILE YPDPVGHVFS
0101: EAFWKAGVFP NHPRICTLLS KKFPEHFSKL QLERIDKFSL DSLHDGAELH LQSLEPWIQL LLDLMAFREQ ALRLILDLSS TVITLLPHQN SLILHAFMDL
0201: FCAFVRVNLF AEKIPRKMLL QVYNLLHALS RNDRDCDFYH RLVQFIDSYD PPLKGLQEDL NFVSPRIGEV LEAVGPSIFL SADTRKLRNE GFLSPYHPRF
0301: PDILTNSAHP MRAQDLANVT SYREWVLLGY LVCPDELLRV TSIDIALVVL KENLVVTLFR DEVSLYQMVC EKEFGIGISF ASADSINLTM QYILLHEDYQ
0401: LYVLPRVLES KKMAKSGRTK QKEADLEYSV AKQVEKMISE VHEQALQLCD TIHRERRILL KQEIGRMVLF FTDQPSLLAP NIQMVFSALA LAQSEVLWYF
0501: QHAGIASSRS KAARVIPVDI DPNDPTIGFL LDGMDRLCCL VRKYISAARG YALSYLSSSA GRIRYLMGTP GIVALDLDPT LKGLFQRIVQ HLESIPKAQG
0601: ENVSAITCDL SDFRKDWLSI LMIVTSSRSS INIRHLEKAT VSTGKEGLLS EGNAAYNWSR CVDELESQLS KHGSLKKLYF YHQHLTTVFR NTMFGPEGRP
0701: QHCCAWLSVA SSFPECASLI IPEEVTKFGR DAVLYVESLI ESIMGGLEGL INILDSEGGF GALESQLLPE QAAAYLNNAS RISAPSVKSP RVVGGFTLPG
0801: HESYPENNKS IKMLEAAIQR LTNLCSILND MEPICVINHV FVLREYMREC ILGNFKRRFL TALQTDNDLQ RPSVLESLIR RHMGIVHLAE QHVSMDLTQG
0901: IREILLTEAF SGPVSSLHTF EKPAEQQQTT GSAVEVVCNW YMDNIIKDVS GAGILFAPRH KYFKSTRPVG GYFAESVTDL KELQAFVRIF GGYGVDRLDR
1001: MMKVHTAALV NCIETSLRSN RELIEAAAAS MHSGDRVERD ASVRQIVDLD TVIGFCIEAG QALAFDDLLA EASGAVLEDN ASLIHSMISG IVEHIPEEIP
1101: EKKEIRRIKG VANGVGVAGD HDSEWVRLIL EEVGGANDNS WSLLPYFFAS FMTSNAWNTT GFNIETGGFS NNIHCLARCI SAVIAGSEYV RLQREYQQQH
1201: QSLSNGHHSS ENLDSEFPPR VTAEASIKSS MLLFVKFAAS IVLDSWSEAN RSHLVAKLIF LDQLCEISPY LPRSSLESHV PYTILRSIYT QYYSNTPSTP
1301: LSTASPYHSP SVSLIHASPS MKNSTTPQRG SGSGSSSTAA PDSGYFKGSS SSLYGQEHYT ESETGNSRNN ENNNNNKQRG SSRRSGPLDY SSSHKGGSGS
1401: NSTGPSPLPR FAVSRSGPIS YKQHN
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)