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AT2G34660.1
Subcellular Consensus
(Prediction and Experimental)
min: heatmap :max

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SUBAcon:
vacuole 1.000
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
  • PMID:31520498 (2020): mitochondrion
  • PMID:30875866 (2019): plasma membrane
  • PMID:26748395 (2016): plant-type vacuole plant-type vacuole membrane
  • PMID:25900983 (2015): Golgi trans-Golgi network
  • PMID:25641898 (2015): plasma membrane
  • PMID:23903016 (2013): plant-type vacuole plant-type vacuole membrane
  • PMID:23673981 (2013): plastid plastid stroma plastoglobules
  • PMID:22923678 (2012): plant-type vacuole
  • PMID:21988472 (2012): plant-type vacuole plant-type vacuole membrane
  • PMID:21433285 (2011): plasma membrane
  • PMID:19334764 (2009): plasma membrane
  • PMID:17151019 (2007): plant-type vacuole
  • PMID:16618929 (2006): plant-type vacuole
  • PMID:15215502 (2004): plant-type vacuole
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no PPI data
Description (TAIR10) protein_coding : multidrug resistance-associated protein 2
Curator
Summary (TAIR10)
encodes a multidrug resistance-associated protein that is MgATP-energized glutathione S-conjugate pump. The expression of this gene is upregulated by herbicide safeners such as benoxacor and fenclorim.
Computational
Description (TAIR10)
multidrug resistance-associated protein 2 (MRP2); FUNCTIONS IN: ATPase activity, coupled to transmembrane movement of substances; INVOLVED IN: response to cyclopentenone; LOCATED IN: vacuolar membrane, plasma membrane, vacuole, plant-type vacuole; EXPRESSED IN: 26 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: ATPase, AAA+ type, core (InterPro:IPR003593), ABC transporter-like (InterPro:IPR003439), ABC transporter, transmembrane domain, type 1 (InterPro:IPR011527), ABC transporter integral membrane type 1 (InterPro:IPR017940), ABC transporter, transmembrane domain (InterPro:IPR001140), ABC transporter, conserved site (InterPro:IPR017871); BEST Arabidopsis thaliana protein match is: multidrug resistance-associated protein 1 (TAIR:AT1G30400.2); Has 677853 Blast hits to 353182 proteins in 3940 species: Archae - 12495; Bacteria - 548354; Metazoa - 12805; Fungi - 8204; Plants - 5931; Viruses - 21; Other Eukaryotes - 90043 (source: NCBI BLink).
Protein Annotations
BioCyc:ARA:AT2G34660-MONOMERBioCyc:ARA:GQT-1610-MONOMERBioGrid:3377EC:3.6.3.44
eggNOG:COG1132eggNOG:KOG0054EMBL:AC003096EMBL:AF014960
EMBL:AF020288EMBL:AF020289EMBL:CP002685EMBL:U96400
EMBL:Z26467EnsemblPlants:AT2G34660EnsemblPlants:AT2G34660.1EnsemblPlants:AT2G34660.2
entrez:818031Gene3D:3.40.50.300GeneID:818031Genevisible:Q42093
GO:GO:0000325GO:GO:0005524GO:GO:0005773GO:GO:0005774
GO:GO:0008559GO:GO:0016021GO:GO:0042626GO:GO:1902417
GO:GO:1902418Gramene:AT2G34660.1Gramene:AT2G34660.2hmmpanther:PTHR24223
hmmpanther:PTHR24223:SF251InParanoid:Q42093IntAct:Q42093InterPro:IPR003439
InterPro:IPR003593InterPro:IPR011527InterPro:IPR017871InterPro:IPR027417
iPTMnet:Q42093KEGG:ath:AT2G34660ncoils:CoilOMA:QPPRYEK
PaxDb:Q42093Pfam:PF00005Pfam:PF00664Pfam:Q42093
Pfscan:PS50893Pfscan:PS50929PhylomeDB:Q42093PIR:T01369
PRIDE:Q42093PRO:PR:Q42093PROSITE:PS00211PROSITE:PS50893
PROSITE:PS50929ProteinModelPortal:Q42093Proteomes:UP000006548Reactome:R-ATH-2142850
Reactome:R-ATH-382556RefSeq:NP_001189675.1RefSeq:NP_181013.1scanprosite:PS00211
SMART:SM00382SMR:Q42093STRING:3702.AT2G34660.1SUPFAM:SSF52540
SUPFAM:SSF90123TAIR:AT2G34660tair10-symbols:ABCC2tair10-symbols:AtABCC2
tair10-symbols:ATMRP2tair10-symbols:EST4tair10-symbols:MRP2TCDB:3.A.1.208.5
TMHMM:TMhelixUniGene:At.19665UniProt:Q42093
Coordinates (TAIR10) chr2:+:14603267..14612387
Molecular Weight (calculated) 182140.00 Da
IEP (calculated) 6.36
GRAVY (calculated) 0.02
Length 1623 amino acids
Sequence (TAIR10)
(BLAST)
0001: MGFEFIEWYC KPVPNGVWTK QVANAFGAYT PCATDSFVLG ISQLVLLVLC LYRIWLALKD HKVERFCLRS RLYNYFLALL AAYATAEPLF RLIMGISVLD
0101: FDGPGLPPFE AFGLGVKAFA WGAVMVMILM ETKIYIRELR WYVRFAVIYA LVGDMVLLNL VLSVKEYYSS YVLYLYTSEV GAQVLFGILL FMHLPNLDTY
0201: PGYMPVRSET VDDYEYEEIS DGQQICPEKH ANIFDKIFFS WMNPLMTLGS KRPLTEKDVW YLDTWDQTET LFTSFQHSWD KELQKPQPWL LRALNNSLGG
0301: RFWWGGFWKI GNDCSQFVGP LLLNQLLKSM QEDAPAWMGY IYAFSIFVGV VFGVLCEAQY FQNVMRVGYR LRSALIAAVF RKSLRLTNEG RRKFQTGKIT
0401: NLMTTDAESL QQICQSLHTM WSAPFRIIIA LILLYQQLGV ASLIGALLLV LMFPLQTVII SKMQKLTKEG LQRTDKRIGL MNEVLAAMDT VKCYAWENSF
0501: QSKVQTVRDD ELSWFRKSQL LGALNMFILN SIPVLVTIVS FGVFTLLGGD LTPARAFTSL SLFAVLRFPL FMLPNIITQV VNANVSLKRL EEVLATEERI
0601: LLPNPPIEPG EPAISIRNGY FSWDSKGDRP TLSNINLDVP LGSLVAVVGS TGEGKTSLIS AILGELPATS DAIVTLRGSV AYVPQVSWIF NATVRDNILF
0701: GSPFDREKYE RAIDVTSLKH DLELLPGGDL TEIGERGVNI SGGQKQRVSM ARAVYSNSDV YIFDDPLSAL DAHVGQQVFE KCIKRELGQK TRVLVTNQLH
0801: FLSQVDRIVL VHEGTVKEEG TYEELSSNGP LFQRLMENAG KVEEYSEENG EAEADQTAEQ PVANGNTNGL QMDGSDDKKS KEGNKKGGKS VLIKQEERET
0901: GVVSWRVLKR YQDALGGAWV VMMLLLCYVL TEVFRVTSST WLSEWTDAGT PKSHGPLFYN LIYALLSFGQ VLVTLTNSYW LIMSSLYAAK KLHDNMLHSI
1001: LRAPMSFFHT NPLGRIINRF AKDLGDIDRT VAVFVNMFMG QVSQLLSTVV LIGIVSTLSL WAIMPLLVLF YGAYLYYQNT AREVKRMDSI SRSPVYAQFG
1101: EALNGLSTIR AYKAYDRMAD INGRSMDNNI RFTLVNMGAN RWLGIRLETL GGLMIWLTAS FAVMQNGRAE NQQAFASTMG LLLSYALNIT SLLTGVLRLA
1201: SLAENSLNAV ERVGNYIEIP PEAPPVIENN RPPPGWPSSG SIKFEDVVLR YRPQLPPVLH GVSFFIHPTD KVGIVGRTGA GKSSLLNALF RIVEVEKGRI
1301: LIDDCDVGKF GLMDLRKVLG IIPQSPVLFS GTVRFNLDPF GEHNDADLWE SLERAHLKDT IRRNPLGLDA EVSEAGENFS VGQRQLLSLS RALLRRSKIL
1401: VLDEATAAVD VRTDALIQKT IREEFKSCTM LIIAHRLNTI IDCDKILVLD SGRVQEFSSP ENLLSNEGSS FSKMVQSTGA ANAEYLRSLV LDNKRAKDDS
1501: HHLQGQRKWL ASSRWAAAAQ FALAASLTSS HNDLQSLEIE DDSSILKRTN DAVVTLRSVL EGKHDKEIAE SLEEHNISRE GWLSSLYRMV EGLAVMSRLA
1601: RNRMQQPDYN FEGNTFDWDN VEM
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)