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AT2G30950.1
Subcellular Consensus
(Prediction and Experimental)

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SUBAcon:
plastid 1.000
ASURE: plastid
What is SUBAcon?
What is ASURE?
SUBAcon computations
Experimental Localisations and PPI
FP MS/MS PPI
  • PMID:27943495 (2017): mitochondrion
  • PMID:27122571 (2016): mitochondrion
  • PMID:25900983 (2015): Golgi trans-Golgi network
  • PMID:25900983 (2015): Golgi trans-Golgi network early endosome
  • PMID:25900983 (2015): Golgi trans-Golgi network multivesicular body
  • PMID:24872594 (2014): plastid plastid envelope
  • PMID:24872594 (2014): plastid plastid thylakoid
  • PMID:24361574 (2014): plastid plastid stroma
  • PMID:23851315 (2013): plastid
  • PMID:23667806 (2013): plastid plastid thylakoid
  • PMID:23549413 (2013): plastid
  • PMID:23390424 (2013): plastid plastid envelope
  • PMID:21531424 (2011): plastid
  • PMID:21433285 (2011): plasma membrane
  • PMID:20061580 (2010): plastid plastid thylakoid
  • PMID:19676087 (2009): plastid
  • PMID:19334764 (2009): plasma membrane
  • PMID:18633119 (2008): plastid plastid thylakoid
  • PMID:18431481 (2008): plastid plastid thylakoid
  • PMID:16648217 (2006): plastid
  • PMID:15322131 (2004): plastid
  • PMID:15028209 (2004): plastid
  • PMID:14729914 (2004): plastid
  • PMID:12938931 (2003): plastid
  • PMID:11719511 (2002): plastid
SUBAcon links
AGI-AGI relationships
Coexpression PPI
Description (TAIR10) protein_coding : FtsH extracellular protease family
Curator
Summary (TAIR10)
Metalloprotease that functions in thylakoid membrane biogenesis. Involved in the repair of PSII following damaged incurred during photoinhibition. Forms a complex with VAR1. Mutants show a variegated phenotype, which decreases during development. Transcript and protein levels increase with light intensity.
Computational
Description (TAIR10)
VARIEGATED 2 (VAR2); FUNCTIONS IN: metallopeptidase activity, ATP-dependent peptidase activity, ATPase activity, zinc ion binding; INVOLVED IN: photoinhibition, oxygen and reactive oxygen species metabolic process, thylakoid membrane organization, PSII associated light-harvesting complex II catabolic process, protein catabolic process; LOCATED IN: in 6 components; EXPRESSED IN: 26 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Peptidase M41, FtsH (InterPro:IPR005936), ATPase, AAA+ type, core (InterPro:IPR003593), ATPase, AAA-type, core (InterPro:IPR003959), ATPase, AAA-type, conserved site (InterPro:IPR003960), Peptidase M41 (InterPro:IPR000642), Peptidase M41, FtsH extracellular (InterPro:IPR011546); BEST Arabidopsis thaliana protein match is: FTSH protease 8 (TAIR:AT1G06430.1); Has 42824 Blast hits to 40381 proteins in 3333 species: Archae - 1597; Bacteria - 18199; Metazoa - 4991; Fungi - 3835; Plants - 3350; Viruses - 34; Other Eukaryotes - 10818 (source: NCBI BLink).
Protein Annotations
BioGrid:2995BRENDA:3.4.24.B20EC:3.4.24.-eggNOG:COG0465eggNOG:KOG0731EMBL:AC004669EMBL:AF135189
EMBL:AK221155EMBL:AY045599EMBL:AY093791EMBL:CP002685EnsemblPlants:AT2G30950EnsemblPlants:AT2G30950.1entrez:817646
Gene3D:3.40.50.300GeneID:817646Genevisible:O80860GO:GO:0004176GO:GO:0004222GO:GO:0005524GO:GO:0006508
GO:GO:0007275GO:GO:0008237GO:GO:0009507GO:GO:0009534GO:GO:0009535GO:GO:0009579GO:GO:0009735
GO:GO:0009941GO:GO:0010027GO:GO:0010205GO:GO:0010206GO:GO:0010304GO:GO:0016020GO:GO:0016021
GO:GO:0030163GO:GO:0031977GO:GO:0046872GO:GO:0072593Gramene:AT2G30950.1HAMAP:MF_01458hmmpanther:PTHR23076
hmmpanther:PTHR23076:SF60HOGENOM:HOG000217276InParanoid:O80860IntAct:O80860InterPro:IPR000642InterPro:IPR003593InterPro:IPR003959
InterPro:IPR003960InterPro:IPR005936InterPro:IPR027417KEGG:ath:AT2G30950KO:K03798MEROPS:M41.005OMA:TLCPGHD
PaxDb:O80860Pfam:O80860Pfam:PF00004Pfam:PF01434PhylomeDB:O80860PIR:F84714PRIDE:O80860
PRO:PR:O80860PROSITE:PS00674ProteinModelPortal:O80860Proteomes:UP000006548RefSeq:NP_850156.1scanprosite:PS00674SMART:SM00382
SMR:O80860STRING:3702.AT2G30950.1SUPFAM:SSF140990SUPFAM:SSF52540TAIR:AT2G30950tair10-symbols:FTSH2tair10-symbols:VAR2
TIGRfam:TIGR01241TIGRFAMs:TIGR01241TMHMM:TMhelixUniGene:At.22024UniGene:At.71129UniGene:At.75189UniProt:O80860
World-2DPAGE:0003:O80860
Coordinates (TAIR10) chr2:+:13174692..13177064
Molecular Weight (calculated) 74161.80 Da
IEP (calculated) 6.24
GRAVY (calculated) -0.14
Length 695 amino acids
Sequence (TAIR10)
(BLAST)
001: MAASSACLVG NGLSVNTTTK QRLSKHFSGR QTSFSSVIRT SKVNVVKASL DGKKKQEGRR DFLKILLGNA GVGLVASGKA NADEQGVSSS RMSYSRFLEY
101: LDKDRVNKVD LYENGTIAIV EAVSPELGNR VERVRVQLPG LSQELLQKLR AKNIDFAAHN AQEDQGSVLF NLIGNLAFPA LLIGGLFLLS RRSGGGMGGP
201: GGPGNPLQFG QSKAKFQMEP NTGVTFDDVA GVDEAKQDFM EVVEFLKKPE RFTAVGAKIP KGVLLIGPPG TGKTLLAKAI AGEAGVPFFS ISGSEFVEMF
301: VGVGASRVRD LFKKAKENAP CIVFVDEIDA VGRQRGTGIG GGNDEREQTL NQLLTEMDGF EGNTGVIVVA ATNRADILDS ALLRPGRFDR QVSVDVPDVK
401: GRTDILKVHA GNKKFDNDVS LEIIAMRTPG FSGADLANLL NEAAILAGRR ARTSISSKEI DDSIDRIVAG MEGTVMTDGK SKSLVAYHEV GHAVCGTLTP
501: GHDAVQKVTL IPRGQARGLT WFIPSDDPTL ISKQQLFARI VGGLGGRAAE EIIFGDSEVT TGAVGDLQQI TGLARQMVTT FGMSDIGPWS LMDSSAQSDV
601: IMRMMARNSM SEKLAEDIDS AVKKLSDSAY EIALSHIKNN REAMDKLVEV LLEKETIGGD EFRAILSEFT EIPPENRVPS STTTTPASAP TPAAV
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)