AT2G20990.1
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Subcellular Consensus
(Prediction and Experimental) min:  :max.
SUBAcon:endoplasmic reticulum 0.500 plasma membrane 0.500 ASURE: endoplasmic reticulum,plasma membrane What is SUBAcon? |
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| Experimental Localisations and PPI |
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SUBAcon links
AGI-AGI relationships |
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| Description (TAIR10) | protein_coding : synaptotagmin A | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Curator Summary (TAIR10) |
Encodes a plasma membrane localized protein with similarity to synaptotagmins, a class of membrane trafficking proteins. SYT1 is expressed in all tissues. Loss of function mutations show hypersensitivity to NaCl and electrolyte leakage from the plasma membrane. SYT1 also affects calcium dependent freezing tolerance. SYT1 probably plays a role in membrane repair such as membrane resealing after freezing induced damage. Regulates endocytosis endosome recycling at the plasma membrane, but not membrane traffic along the secretory pathway. | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Computational Description (TAIR10) |
synaptotagmin A (SYTA); FUNCTIONS IN: molecular_function unknown; INVOLVED IN: in 7 processes; LOCATED IN: endosome, plasma membrane, vacuole, membrane; EXPRESSED IN: whole plant, guard cell, cultured cell, callus, leaf; EXPRESSED DURING: seedling growth; CONTAINS InterPro DOMAIN/s: C2 membrane targeting protein (InterPro:IPR018029), C2 calcium/lipid-binding domain, CaLB (InterPro:IPR008973), C2 region (InterPro:IPR020477), C2 calcium-dependent membrane targeting (InterPro:IPR000008); BEST Arabidopsis thaliana protein match is: Calcium-dependent lipid-binding (CaLB domain) family protein (TAIR:AT1G20080.1); Has 7068 Blast hits to 5182 proteins in 270 species: Archae - 0; Bacteria - 0; Metazoa - 4491; Fungi - 774; Plants - 1307; Viruses - 0; Other Eukaryotes - 496 (source: NCBI BLink). | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Protein Annotations |
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| Coordinates (TAIR10) | chr2:+:9014827..9017829 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Molecular Weight (calculated) | 61747.50 Da | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| IEP (calculated) | 7.67 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| GRAVY (calculated) | -0.26 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Length | 541 amino acids | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Sequence (TAIR10) (BLAST) |
001: MGFFSTILGF CGFGVGISLG LVIGYVLFVY LLPNDVKDPE IRSIADQDPK AMLRMLPEIP LWVKNPDFDR VDWINRFLEY MWPYLDKAIC KTAKNIAKPI 101: IEEQIPKYKI DSVEFETLTL GSLPPTFQGM KVYLTDEKEL IMEPCLKWAA NPNILVAIKA FGLKATVQVV DLQVFAQPRI TLKPLVPSFP CFANIYVSLM 201: EKPHVDFGLK LGGADLMSIP GLYRFVQEQI KDQVANMYLW PKTLVVPILD PAKAFRRPVG IVHVKVVRAV GLRKKDLMGG ADPFVKIKLS EDKIPSKKTT 301: VKHKNLNPEW NEEFKFSVRD PQTQVLEFSV YDWEQVGNPE KMGMNVLALK EMVPDEHKAF TLELRKTLDG GEDGQPPDKY RGKLEVELLY KPFTEEEMPK 401: GFEETQAVQK APEGTPAAGG MLVVIVHSAE DVEGKHHTNP YVRIYFKGEE RKTKHVKKNR DPRWNEEFTF MLEEPPVREK LHVEVLSTSS RIGLLHPKET 501: LGYVDIPVVD VVNNKRMNQK FHLIDSKNGK IQIELEWRTA S |
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| See Also |
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Citation
If you find this resource useful please cite one of the following publications:
Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)
Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)