AT2G20300.1
|
Subcellular Consensus
(Prediction and Experimental) min:  :max.
SUBAcon:plasma membrane 1.000 What is SUBAcon? |
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Experimental Localisations and PPI |
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
|
SUBAcon links
AGI-AGI relationships |
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Description (TAIR10) | protein_coding : Protein kinase superfamily protein | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Curator Summary (TAIR10) |
Encodes ABNORMAL LEAF SHAPE 2 (ALE2), a receptor-like protein kinase (RLK) with a cluster of basic amino acid residues followed by a cysteine-containing sequence in the putative extracellular domain. Function together with ACR4 (Arabidopsis homolog of the Crinkly4) and ALE1 in positively regulating protoderm-specific gene expression and for the formation of leafy organs. ale2 mutants have various epidermal defects, including disorganization of epidermis-related tissues, defects in the leaf cuticle and the fusion of organs. | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Computational Description (TAIR10) |
Abnormal Leaf Shape 2 (ALE2); FUNCTIONS IN: kinase activity; INVOLVED IN: shoot development, organ formation, protoderm histogenesis, cuticle development; LOCATED IN: plasma membrane; EXPRESSED IN: 15 plant structures; EXPRESSED DURING: 6 growth stages; CONTAINS InterPro DOMAIN/s: Protein kinase, ATP binding site (InterPro:IPR017441), Protein kinase, catalytic domain (InterPro:IPR000719), Serine-threonine/tyrosine-protein kinase (InterPro:IPR001245), Protein kinase-like domain (InterPro:IPR011009), Serine/threonine-protein kinase, active site (InterPro:IPR008271); BEST Arabidopsis thaliana protein match is: Protein kinase superfamily protein (TAIR:AT5G56890.1); Has 119232 Blast hits to 117654 proteins in 4402 species: Archae - 117; Bacteria - 14202; Metazoa - 43938; Fungi - 9729; Plants - 33678; Viruses - 349; Other Eukaryotes - 17219 (source: NCBI BLink). | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Protein Annotations |
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Coordinates (TAIR10) | chr2:-:8756475..8759845 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Molecular Weight (calculated) | 81637.80 Da | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| IEP (calculated) | 8.11 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| GRAVY (calculated) | -0.18 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Length | 744 amino acids | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Sequence (TAIR10) (BLAST) |
001: MRNFAMLLLL ILLLHSLASF PICFARLFPM SLPFTRSKAH QMHFFHPYLN PSVAPTPSPA FSPNPSRIPP LRHKGHHRHR RWHLRRNATA VSPSSHDCQQ 101: TCVEPLTSTP FGSPCGCVFP MKVQLLLSVA PFSIFPVTNE LEIEVAAGTY LEQSQVKIMG ASADSENQGK TVVDINLVPL GEKFDNTTAT LIYQRFRHKK 201: VPLNETVFGD YEVTHISYPG IPSSSPNGDV TGDAPGGLPI PINATTFANK SQGIGFRTIA IIALSGFVLI LVLVGAISII VKWKKIGKSS NAVGPALAPS 301: INKRPGAGSM FSSSARSSGS DSLMSSMATC ALSVKTFTLS ELEKATDRFS AKRVLGEGGF GRVYQGSMED GTEVAVKLLT RDNQNRDREF IAEVEMLSRL 401: HHRNLVKLIG ICIEGRTRCL IYELVHNGSV ESHLHEGTLD WDARLKIALG AARGLAYLHE DSNPRVIHRD FKASNVLLED DFTPKVSDFG LAREATEGSQ 501: HISTRVMGTF GYVAPEYAMT GHLLVKSDVY SYGVVLLELL TGRRPVDMSQ PSGEENLVTW ARPLLANREG LEQLVDPALA GTYNFDDMAK VAAIASMCVH 601: QEVSHRPFMG EVVQALKLIY NDADETCGDY CSQKDSSVPD SADFKGDLAP SDSSWWNLTP RLRYGQASSF ITMDYSSGPL EDMENRPHSA SSIPRVGGLI 701: LPNRSGPLRP MRSRRNFFRL RGSMSEHGGP SSSRHLWSGN GDWL |
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| See Also |
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Citation
If you find this resource useful please cite one of the following publications:
Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)
Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)