suba logo
AT2G17950.1
Subcellular Consensus
(Prediction and Experimental)
min: heatmap :max

.
SUBAcon:
nucleus 1.000
ASURE: nucleus
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no coexpression data
Description (TAIR10) protein_coding : Homeodomain-like superfamily protein
Curator
Summary (TAIR10)
Homeobox gene controlling the stem cell pool. Expressed in the stem cell organizing center of meristems. Required to keep the stem cells in an undifferentiated state. Regulation of WUS transcription is a central checkpoint in stem cell control. The size of the WUS expression domain controls the size of the stem cell population through WUS indirectly activating the expression of CLAVATA3 (CLV3) in the stem cells and CLV3 repressing WUS transcription through the CLV1 receptor kinase signaling pathway. Repression of WUS transcription through AGAMOUS (AG) activity controls stem cell activity in the determinate floral meristem. Binds to TAAT element core motif. WUS is also involved in cell differentiation during anther development.
Computational
Description (TAIR10)
WUSCHEL (WUS); CONTAINS InterPro DOMAIN/s: Homeobox (InterPro:IPR001356), Homeodomain-like (InterPro:IPR009057); BEST Arabidopsis thaliana protein match is: WUSCHEL related homeobox 1 (TAIR:AT3G18010.1); Has 617 Blast hits to 617 proteins in 63 species: Archae - 0; Bacteria - 0; Metazoa - 29; Fungi - 2; Plants - 575; Viruses - 0; Other Eukaryotes - 11 (source: NCBI BLink).
Protein Annotations
BioGrid:1662eggNOG:ENOG410IX2WeggNOG:ENOG410YSE9EMBL:AC006201
EMBL:AJ012310EMBL:AY086385EMBL:CP002685EnsemblPlants:AT2G17950
EnsemblPlants:AT2G17950.1entrez:816305ExpressionAtlas:Q9SB92Gene3D:1.10.10.60
GeneID:816305Genevisible:Q9SB92GO:GO:0003677GO:GO:0003700
GO:GO:0005634GO:GO:0006351GO:GO:0006355GO:GO:0019827
GO:GO:0048477GO:GO:0048653GO:GO:0080166Gramene:AT2G17950.1
hmmpanther:PTHR24326hmmpanther:PTHR24326:SF123InParanoid:Q9SB92IntAct:Q9SB92
InterPro:IPR001356InterPro:IPR009057KEGG:ath:AT2G17950OMA:MEQDCSM
PaxDb:Q9SB92Pfam:PF00046Pfam:Q9SB92Pfscan:PS50071
PhylomeDB:Q1PF51PhylomeDB:Q9SB92PIR:D84558PIR:T00829
PRIDE:Q9SB92PRO:PR:Q9SB92PROSITE:PS50071ProteinModelPortal:Q9SB92
Proteomes:UP000006548RefSeq:NP_565429.1SMART:SM00389STRING:3702.AT2G17950.1
SUPFAM:SSF46689TAIR:AT2G17950tair10-symbols:PGA6tair10-symbols:WUS
tair10-symbols:WUS1UniGene:At.51UniProt:Q1PF51UniProt:Q9SB92
Coordinates (TAIR10) chr2:-:7809100..7810671
Molecular Weight (calculated) 33191.40 Da
IEP (calculated) 8.05
GRAVY (calculated) -1.04
Length 292 amino acids
Sequence (TAIR10)
(BLAST)
001: MEPPQHQHHH HQADQESGNN NNNKSGSGGY TCRQTSTRWT PTTEQIKILK ELYYNNAIRS PTADQIQKIT ARLRQFGKIE GKNVFYWFQN HKARERQKKR
101: FNGTNMTTPS SSPNSVMMAA NDHYHPLLHH HHGVPMQRPA NSVNVKLNQD HHLYHHNKPY PSFNNGNLNH ASSGTECGVV NASNGYMSSH VYGSMEQDCS
201: MNYNNVGGGW ANMDHHYSSA PYNFFDRAKP LFGLEGHQEE EECGGDAYLE HRRTLPLFPM HGEDHINGGS GAIWKYGQSE VRPCASLELR LN
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)