suba logo
AT2G17265.1
Subcellular Consensus
(Prediction and Experimental)

min: heatmap :max

.
SUBAcon:
plastid 1.000
ASURE: plastid
What is SUBAcon?
What is ASURE?
SUBAcon computations
Experimental Localisations and PPI
FP MS/MS PPI
  • PMID:26572690 (2016): extracellular region plant-type cell wall
  • PMID:24872594 (2014): plastid plastid stroma
  • PMID:24361574 (2014): plastid plastid stroma
  • PMID:21531424 (2011): plastid
  • PMID:20423899 (2010): plastid
  • PMID:20061580 (2010): plastid plastid stroma
  • PMID:18431481 (2008): plastid
FP Images

onion epidermal cell layer (peroxisomal marker)

At2g-GFP-17265
(full-length)
RFP-peroxisomal markeroverlay

Images by John Bussel
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no PPI data
Description (TAIR10) protein_coding : homoserine kinase
Curator
Summary (TAIR10)
Encodes a homoserine kinase (HSK) which produces O-phospho-L-homoserine (HserP), a compound at the branching point of methionine and threonine biosynthesis. HSK is found in the stromal fraction of chloroplasts. Mutants are susceptible to downy mildew fungus Hyaloperonospora parasitica.
Computational
Description (TAIR10)
homoserine kinase (HSK); FUNCTIONS IN: homoserine kinase activity; INVOLVED IN: methionine biosynthetic process, threonine biosynthetic process, response to fungus, response to bacterium; LOCATED IN: chloroplast stroma, chloroplast; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: GHMP kinase, ATP-binding, conserved site (InterPro:IPR006203), Ribosomal protein S5 domain 2-type fold (InterPro:IPR020568), GHMP kinase (InterPro:IPR006204), Ribosomal protein S5 domain 2-type fold, subgroup (InterPro:IPR014721), Homoserine kinase (InterPro:IPR000870), GHMP kinase, C-terminal (InterPro:IPR013750); BEST Arabidopsis thaliana protein match is: homoserine kinase, putative / HSK, putative (TAIR:AT4G35295.1); Has 6092 Blast hits to 6088 proteins in 1935 species: Archae - 296; Bacteria - 4868; Metazoa - 7; Fungi - 124; Plants - 47; Viruses - 0; Other Eukaryotes - 750 (source: NCBI BLink).
Protein Annotations
BioCyc:MetaCyc:MONOMER-1961BRENDA:2.7.1.39EC:2.7.1.39eggNOG:COG0083eggNOG:KOG1537EMBL:AF082525EMBL:AK117871
EMBL:AY128313EMBL:BT001174EMBL:CP002685EnsemblPlants:AT2G17265EnsemblPlants:AT2G17265.1entrez:816232Gene3D:3.30.230.10
Gene3D:3.30.70.890GeneID:816232Genevisible:Q8L7R2GO:GO:0004413GO:GO:0005524GO:GO:0006952GO:GO:0009086
GO:GO:0009088GO:GO:0009507GO:GO:0009570GO:GO:0009617GO:GO:0009620Gramene:AT2G17265.1gramene_pathway:2.7.1.39
gramene_pathway:HOMOSER-THRESYN-PWYgramene_pathway:PWY-702gramene_plant_reactome:1119400gramene_plant_reactome:6876595HAMAP:MF_00384hmmpanther:PTHR20861hmmpanther:PTHR20861:SF1
HOGENOM:HOG000247197InParanoid:Q8L7R2InterPro:IPR000870InterPro:IPR006203InterPro:IPR006204InterPro:IPR013750InterPro:IPR014721
InterPro:IPR020568KEGG:00260+2.7.1.39KEGG:ath:AT2G17265KO:K00872OMA:FVHICKVPaxDb:Q8L7R2Pfam:PF00288
Pfam:PF08544Pfam:Q8L7R2PhylomeDB:Q8L7R2PIRSF:PIRSF000676PRIDE:Q8L7R2PRO:PR:Q8L7R2ProMEX:Q8L7R2
PROSITE:PS00627ProteinModelPortal:Q8L7R2Proteomes:UP000006548RefSeq:NP_179318.1SABIO-RK:Q8L7R2scanprosite:PS00627SMR:Q8L7R2
STRING:3702.AT2G17265.1SUPFAM:SSF54211SUPFAM:SSF55060TAIR:AT2G17265tair10-symbols:DMR1tair10-symbols:HSKTIGRfam:TIGR00191
TIGRFAMs:TIGR00191UniGene:At.10492UniGene:At.26823UniPathway:UPA00050UniProt:Q8L7R2
Coordinates (TAIR10) chr2:+:7508606..7509718
Molecular Weight (calculated) 38530.90 Da
IEP (calculated) 8.48
GRAVY (calculated) 0.27
Length 370 amino acids
Sequence (TAIR10)
(BLAST)
001: MASLCFQSPS KPISYFQPKS NPSPPLFAKV SVFRCRASVQ TLVAVEPEPV FVSVKTFAPA TVANLGPGFD FLGCAVDGLG DHVTLRVDPS VRAGEVSISE
101: ITGTTTKLST NPLRNCAGIA AIATMKMLGI RSVGLSLDLH KGLPLGSGLG SSAASAAAAA VAVNEIFGRK LGSDQLVLAG LESEAKVSGY HADNIAPAIM
201: GGFVLIRNYE PLDLKPLRFP SDKDLFFVLV SPDFEAPTKK MRAALPTEIP MVHHVWNSSQ AAALVAAVLE GDAVMLGKAL SSDKIVEPTR APLIPGMEAV
301: KKAALEAGAF GCTISGAGPT AVAVIDSEEK GQVIGEKMVE AFWKVGHLKS VASVKKLDNV GARLVNSVSR
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)