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AT2G16390.1
Subcellular Consensus
(Prediction and Experimental)
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SUBAcon:
nucleus 1.000
ASURE: nucleus
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no PPI data
Description (TAIR10) protein_coding : SNF2 domain-containing protein / helicase domain-containing protein
Curator
Summary (TAIR10)
Putative chromatin remodeling protein, member of a plant-specific subfamily of SWI2/SNF2-like proteins. Mutations nearly eliminate non-CpG methylation at a target promoter but do not affect rDNA or centromere methylation. Cooperates with PolIVb to facilitate RNA-directed de novo methylation and silencing of homologous DNA. Endogenous targets include intergenic regions near retrotransposon LTRs or short RNA encoding sequences that might epigenetically regulate adjacent genes. May be used to establish a basal yet reversible level of silencing in euchromatin.
Computational
Description (TAIR10)
DEFECTIVE IN RNA-DIRECTED DNA METHYLATION 1 (DRD1); FUNCTIONS IN: helicase activity, DNA binding, ATP binding, nucleic acid binding; INVOLVED IN: DNA methylation, production of siRNA involved in RNA interference; LOCATED IN: cellular_component unknown; EXPRESSED IN: 9 plant structures; EXPRESSED DURING: 6 growth stages; CONTAINS InterPro DOMAIN/s: DEAD-like helicase, N-terminal (InterPro:IPR014001), DNA/RNA helicase, C-terminal (InterPro:IPR001650), Helicase, superfamily 1/2, ATP-binding domain (InterPro:IPR014021), SNF2-related (InterPro:IPR000330); BEST Arabidopsis thaliana protein match is: chromatin remodeling 34 (TAIR:AT2G21450.1); Has 13448 Blast hits to 11886 proteins in 1506 species: Archae - 91; Bacteria - 3564; Metazoa - 3285; Fungi - 3284; Plants - 1229; Viruses - 105; Other Eukaryotes - 1890 (source: NCBI BLink).
Protein Annotations
BioCyc:ARA:GQT-2335-MONOMEReggNOG:COG0553eggNOG:KOG0390EMBL:AC007047
EMBL:CP002685EnsemblPlants:AT2G16390EnsemblPlants:AT2G16390.1entrez:816136
Gene3D:3.40.50.300GeneID:816136Genevisible:Q9SIW2GO:GO:0000419
GO:GO:0003677GO:GO:0004386GO:GO:0005524GO:GO:0005634
GO:GO:0006306GO:GO:0031618GO:GO:0032776GO:GO:0035563
GO:GO:0050832GO:GO:0060964GO:GO:0060966GO:GO:0060968
GO:GO:0070829GO:GO:0071360GO:GO:0080188GO:GO:0090577
GO:GO:1900111GO:GO:1900368GO:GO:1900370Gramene:AT2G16390.1
hmmpanther:PTHR10799hmmpanther:PTHR10799:SF611HOGENOM:HOG000029425InParanoid:Q9SIW2
InterPro:IPR000330InterPro:IPR001650InterPro:IPR014001InterPro:IPR027417
iPTMnet:Q9SIW2KEGG:ath:AT2G16390KO:K10875OMA:IVPYEAS
PaxDb:Q9SIW2Pfam:PF00176Pfam:PF00271Pfscan:PS51192
Pfscan:PS51194PhylomeDB:Q9SIW2PIR:G84539PRIDE:Q9SIW2
PRO:PR:Q9SIW2PROSITE:PS51192PROSITE:PS51194ProteinModelPortal:Q9SIW2
Proteomes:UP000006548RefSeq:NP_179232.1SMART:SM00487SMART:SM00490
SMR:Q9SIW2STRING:3702.AT2G16390.1-PSUPFAM:SSF52540TAIR:AT2G16390
tair10-symbols:CHR35tair10-symbols:DMS1tair10-symbols:DRD1UniGene:At.40283
UniProt:Q9SIW2
Coordinates (TAIR10) chr2:+:7097638..7101182
Molecular Weight (calculated) 100235.00 Da
IEP (calculated) 5.02
GRAVY (calculated) -0.35
Length 888 amino acids
Sequence (TAIR10)
(BLAST)
001: MGFVYIVMTG YYKNVHKRKQ NQVDDGPEAK RVKSSAKVID YSNPFAVSNM LEALDSGKFG SVSKELEEIA DMRMDLVKRS IWLYPSLAYT VFEAEKTMDN
101: QQVVEGVINL DDDDDDDTDV EKKALCVVPS SSEIVLLDSD DEDNERQRPM YQFQSTLVQH QKNQGDVTPL IPQCSFEEVD LGRGKEMPSA IKAIVEGQTS
201: RGKVLPIENG VVNEKGVYVG VEEDDSDNES EAADEDLGNI WNEMALSIEC SKDVARETSH KEKADVVEDC EHSFILKDDM GYVCRVCGVI EKSILEIIDV
301: QFTKAKRNTR TYASETRTKR FGESDNELKF SEEGLMIGGL AAHPTHAAEM KPHQIEGFQF LCSNLVADDP GGCIMAHAPG SGKTFMIISF MQSFLAKYPQ
401: AKPLVVLPKG ILPTWKKEFV RWQVEDIPLL DFYSAKAENR AQQLSILKQW MEKKSILFLG YQQFSTIVCD DTTDSLSCQE ILLKVPSILI LDEGHTPRNE
501: DTNLLQSLAQ VQTPRKVVLS GTLYQNHVKE VFNILNLVRP KFLKLDTSKS AVKRILAYTP CDVRGRLTGS NSDMASMFNE TVEHTLQKSE DFTVKIKVIQ
601: DLREMTKKVL HYYKGDFLDE LPGLADFTVV LNLSPKQLNE VKKLRREKRK FKVSAVGSAI YLHPKLKVFS DKSDDVSDTT MDEMVEKLDL NEGVKAKFFL
701: NLINLCDSAG EKLLVFSQYL IPLKFLERLA ALAKGWKLGK EVFVLTGNTS SEQREWSMET FNSSPDAKIF FGSIKACGEG ISLVGASRIL ILDVPLNPSV
801: TRQAIGRAFR PGQKKMVHAY RLIAGSSPEE EDHNTCFKKE VISKMWFEWN EYCGYQNFEV ETIDVDEAGD TFLESPALRE DIRVLYKR
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)